FR2437833A1 - Treatment of fungal esp. vaginal infections - by administering a chelating agent for zinc ions - Google Patents
Treatment of fungal esp. vaginal infections - by administering a chelating agent for zinc ionsInfo
- Publication number
- FR2437833A1 FR2437833A1 FR7828253A FR7828253A FR2437833A1 FR 2437833 A1 FR2437833 A1 FR 2437833A1 FR 7828253 A FR7828253 A FR 7828253A FR 7828253 A FR7828253 A FR 7828253A FR 2437833 A1 FR2437833 A1 FR 2437833A1
- Authority
- FR
- France
- Prior art keywords
- esp
- administering
- vaginal infections
- fungal
- treatment
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
Abstract
A process is claimed for destroying fungi which require Zn for the secondary metabolic process necessary for their growth. The process comprises administering to infected mammals (esp. humans) an effective amt. of a cpd. (I) capable of chelating Zn ions at a concn. of >=3.5% and a pH of 4.5-10. A typical cpd. (I) is EDTA or its Na2Ca salt. The process is esp. useful for treating vaginal infections due to Candida albicans. Other susceptible fungi include Crytococcus neoformans, torulopsis spp, Candida tropicalis and Penicillium spp.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR7828253A FR2437833A1 (en) | 1978-10-03 | 1978-10-03 | Treatment of fungal esp. vaginal infections - by administering a chelating agent for zinc ions |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR7828253A FR2437833A1 (en) | 1978-10-03 | 1978-10-03 | Treatment of fungal esp. vaginal infections - by administering a chelating agent for zinc ions |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2437833A1 true FR2437833A1 (en) | 1980-04-30 |
FR2437833B1 FR2437833B1 (en) | 1981-07-31 |
Family
ID=9213279
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7828253A Granted FR2437833A1 (en) | 1978-10-03 | 1978-10-03 | Treatment of fungal esp. vaginal infections - by administering a chelating agent for zinc ions |
Country Status (1)
Country | Link |
---|---|
FR (1) | FR2437833A1 (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4399149A (en) * | 1981-01-23 | 1983-08-16 | Shell Oil Company | Fungicides |
EP2227213A1 (en) * | 2007-11-30 | 2010-09-15 | Toltec Pharmaceuticals, Llc | Compositions and methods for treating vaginal infections and pathogenic vaginal biofilms |
-
1978
- 1978-10-03 FR FR7828253A patent/FR2437833A1/en active Granted
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4399149A (en) * | 1981-01-23 | 1983-08-16 | Shell Oil Company | Fungicides |
EP2227213A1 (en) * | 2007-11-30 | 2010-09-15 | Toltec Pharmaceuticals, Llc | Compositions and methods for treating vaginal infections and pathogenic vaginal biofilms |
EP2227213A4 (en) * | 2007-11-30 | 2011-01-05 | Toltec Pharmaceuticals Llc | Compositions and methods for treating vaginal infections and pathogenic vaginal biofilms |
EP2529723A3 (en) * | 2007-11-30 | 2013-04-03 | Toltec Pharmaceuticals, Llc | Compositions and Methods for Treating Vaginal Infections and Pathogenic Vaginal Biofilms |
EP2684574A1 (en) * | 2007-11-30 | 2014-01-15 | Toltec Pharmaceuticals, Llc | Compositions and methods for treating vaginal infections and pathogenic vaginal biofilms |
US8956663B2 (en) | 2007-11-30 | 2015-02-17 | Toltec Pharmaceuticals, Llc | Compositions and methods for treating vaginal infections and pathogenic vaginal biofilms |
Also Published As
Publication number | Publication date |
---|---|
FR2437833B1 (en) | 1981-07-31 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ST | Notification of lapse |