FR2426463A1 - THERAPEUTIC PREPARATION INTENDED FOR THE PARENTERAL ADMINISTRATION OF TRIGLYCERIDES CONTAINING ACYL-CARNITINE - Google Patents
THERAPEUTIC PREPARATION INTENDED FOR THE PARENTERAL ADMINISTRATION OF TRIGLYCERIDES CONTAINING ACYL-CARNITINEInfo
- Publication number
- FR2426463A1 FR2426463A1 FR7913333A FR7913333A FR2426463A1 FR 2426463 A1 FR2426463 A1 FR 2426463A1 FR 7913333 A FR7913333 A FR 7913333A FR 7913333 A FR7913333 A FR 7913333A FR 2426463 A1 FR2426463 A1 FR 2426463A1
- Authority
- FR
- France
- Prior art keywords
- carnitine
- parenteral administration
- therapeutic preparation
- triglycerides containing
- containing acyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Emergency Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Abstract
La présente invention est relative à une composition pour l'alimentation parentérale complémentaire ou totale de patients qui en ont besoin en raison d'un état de choc ou d'un traumatisme. Cette composition comprend une quantité thérapeutiquement efficace de triglycérides et une quantité d'acyl-carnitine, en particulier d'acétyl-carnitine ou d'un sel pharmaceutiquement acceptable de cette dernière, suffisante pour accroître l'oxydation des acides gras libres.The present invention relates to a composition for the complementary or total parenteral nutrition of patients who need it due to a state of shock or trauma. This composition comprises a therapeutically effective amount of triglycerides and an amount of acyl-carnitine, in particular acetyl-carnitine or a pharmaceutically acceptable salt thereof, sufficient to increase the oxidation of free fatty acids.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT49534/78A IT1156769B (en) | 1978-05-25 | 1978-05-25 | THERAPEUTIC APPLICATION OF CARNITINE AND OTHER ACIL DERIVATIVES OF CARNITINE |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2426463A1 true FR2426463A1 (en) | 1979-12-21 |
FR2426463B1 FR2426463B1 (en) | 1982-10-15 |
Family
ID=11270944
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7913329A Pending FR2426462A1 (en) | 1978-05-25 | 1979-05-25 | THERAPEUTIC PREPARATION INTENDED FOR THE PARENTERAL ADMINISTRATION OF TRIGLYCERIDES CONTAINING CARNITINE |
FR7913333A Granted FR2426463A1 (en) | 1978-05-25 | 1979-05-25 | THERAPEUTIC PREPARATION INTENDED FOR THE PARENTERAL ADMINISTRATION OF TRIGLYCERIDES CONTAINING ACYL-CARNITINE |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7913329A Pending FR2426462A1 (en) | 1978-05-25 | 1979-05-25 | THERAPEUTIC PREPARATION INTENDED FOR THE PARENTERAL ADMINISTRATION OF TRIGLYCERIDES CONTAINING CARNITINE |
Country Status (14)
Country | Link |
---|---|
US (1) | US4254147A (en) |
JP (2) | JPS54154513A (en) |
BE (2) | BE876561A (en) |
CA (2) | CA1132907A (en) |
CH (2) | CH637296A5 (en) |
DE (2) | DE2921331A1 (en) |
DK (2) | DK213979A (en) |
FR (2) | FR2426462A1 (en) |
GB (2) | GB2021410B (en) |
IE (2) | IE48124B1 (en) |
IL (2) | IL57372A0 (en) |
IT (1) | IT1156769B (en) |
LU (2) | LU81318A1 (en) |
NL (2) | NL7904141A (en) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2921852A1 (en) * | 1979-05-29 | 1980-12-11 | Fresenius Chem Pharm Ind | LIPID LOWERING AGENT |
IT1120033B (en) * | 1979-10-05 | 1986-03-19 | Sigma Tau Ind Farmaceuti | INCLUDING PHARMACEUTICAL COMPOSITION-CARNITINE SUITABLE FOR PARENTERAL FEEDING |
IT1145362B (en) * | 1980-03-06 | 1986-11-05 | Sigma Tau Ind Farmaceuti | ACYL-DERIVATIVES CLASS OF CARNITINE PROCEDURE FOR THEIR PREPARATION AND THERAPEUTIC USE |
IT1145371B (en) * | 1980-05-30 | 1986-11-05 | Sigma Tau Ind Farmaceuti | ALCOSSI-ACIL CARNITINE PROCEDURE FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM |
DE3026368A1 (en) * | 1980-07-11 | 1982-02-18 | Lentia GmbH Chem. u. pharm. Erzeugnisse - Industriebedarf, 8000 München | NUTRITIONAL SOLUTION FOR COMPLETE PARENTERAL NUTRITION AND FOR ENHANCED ENERGY PRODUCTION |
DE3032300A1 (en) * | 1980-08-27 | 1982-04-01 | Alfred Ing. Wien Lohninger | Parenteral nutrition fatty emulsion - contg. fatty acid tri:glyceride(s), glycerol, carnitine or acyl-carnitine, phospholipid, and carrier or diluent |
IT1157238B (en) * | 1982-10-29 | 1987-02-11 | Sigma Tau Ind Farmaceuti | USE OF 1-CARNITINA TO IMPROVE THE BIOCHEMICAL AND BEHAVIORAL PARAMENTS OF THE SENILE AGE |
IT1190370B (en) * | 1985-06-19 | 1988-02-16 | Zambon Spa | SOLID PHARMACEUTICAL COMPOSITION FOR ORAL USE |
IT1184655B (en) * | 1985-10-14 | 1987-10-28 | Sigma Tau Ind Farmaceuti | USE OF ACETYL L-CARNITINE IN THE THERAPEUTIC TREATMENT OF SHOCK STATES |
US4839159A (en) * | 1988-02-08 | 1989-06-13 | Topicarn, Inc. | Topical L-carnitine composition |
US4883672A (en) * | 1988-04-29 | 1989-11-28 | Shug Austin L | Method for preventing diet induced carnitine deficiency in domesticated dogs and cats |
AU634537B2 (en) * | 1989-03-30 | 1993-02-25 | Kabi Pharmacia Ab | Pharmaceutical lipid composition for parenteral nutrition |
IT1231944B (en) * | 1989-05-05 | 1992-01-16 | Sigma Tau Ind Farmaceuti | PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF PROTOZOOSIS, ESPECIALLY OF TRIPASONOMYASIS INCLUDING D-CARNITINE OR AN ALCANOYL DERIVATIVE OF D-CARNITINE |
US20040034091A1 (en) * | 1991-01-29 | 2004-02-19 | Sigma Tau Industrie Farmaceutiche Riunite S.P.A. | Derivative of dicarboxylic acids having six to twelve carbon atoms and use of these derivatives and dicarboxylic acids alone in the preparation of pharmaceutical compositions for enteral and parenteral nutrition |
US5192804A (en) * | 1991-03-22 | 1993-03-09 | Lonza Inc. | Carnitine-supplemented diet for starter pigs |
IT1291127B1 (en) * | 1997-04-01 | 1998-12-29 | Sigma Tau Ind Farmaceuti | FOOD SUPPLEMENT FOR SUBJECTS DEDICATED TO INTENSE AND PROLONGED PHYSICAL ACTIVITY |
DE19831575A1 (en) * | 1998-07-14 | 2000-02-03 | Mfe Marienfelde Gmbh Unternehm | Feed preparation containing oil |
JP2004519241A (en) * | 2001-03-09 | 2004-07-02 | ソシエテ デ プロデユイ ネツスル ソシエテ アノニム | Composition that improves physiological disorders associated with aging and extends lifespan |
US20050232911A1 (en) * | 2004-04-19 | 2005-10-20 | Schreiber Brian D | Prevention and treatment of metabolic abnormalities associated with excess intramyocellular lipid |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BE639532A (en) * | ||||
US2972565A (en) * | 1958-04-04 | 1961-02-21 | Univ Tennessee Res Corp | Fat composition |
GB1256162A (en) * | 1968-08-16 | 1971-12-08 | Braun Fa B | Improvements in and relating to liquid products for intravenous administration |
US3810994A (en) * | 1972-06-01 | 1974-05-14 | Ethyl Corp | Method and composition for treating obesity |
IT1104165B (en) * | 1978-02-03 | 1985-10-21 | Sigma Tau Ind Farmaceuti | Carnitine compsn. as the racemate or optical isomers - is used to treat hyperlipaemia, hypercholesterolaemia and associated lipid metabolism defects |
-
1978
- 1978-05-25 IT IT49534/78A patent/IT1156769B/en active
-
1979
- 1979-05-23 IL IL57372A patent/IL57372A0/en unknown
- 1979-05-23 IL IL57373A patent/IL57373A0/en unknown
- 1979-05-23 DK DK213979A patent/DK213979A/en not_active Application Discontinuation
- 1979-05-23 DK DK213879A patent/DK213879A/en not_active Application Discontinuation
- 1979-05-23 US US06/041,645 patent/US4254147A/en not_active Expired - Lifetime
- 1979-05-24 CA CA328,442A patent/CA1132907A/en not_active Expired
- 1979-05-24 GB GB7918229A patent/GB2021410B/en not_active Expired
- 1979-05-24 GB GB7918230A patent/GB2021414B/en not_active Expired
- 1979-05-24 CA CA000328443A patent/CA1139224A/en not_active Expired
- 1979-05-25 DE DE19792921331 patent/DE2921331A1/en not_active Ceased
- 1979-05-25 DE DE19792921312 patent/DE2921312A1/en not_active Ceased
- 1979-05-25 LU LU81318A patent/LU81318A1/en unknown
- 1979-05-25 BE BE0/195404A patent/BE876561A/en not_active IP Right Cessation
- 1979-05-25 CH CH491479A patent/CH637296A5/en not_active IP Right Cessation
- 1979-05-25 FR FR7913329A patent/FR2426462A1/en active Pending
- 1979-05-25 FR FR7913333A patent/FR2426463A1/en active Granted
- 1979-05-25 BE BE0/195403A patent/BE876560A/en not_active IP Right Cessation
- 1979-05-25 JP JP6550479A patent/JPS54154513A/en active Pending
- 1979-05-25 NL NL7904141A patent/NL7904141A/en not_active Application Discontinuation
- 1979-05-25 CH CH491379A patent/CH637295A5/en not_active IP Right Cessation
- 1979-05-25 LU LU81316A patent/LU81316A1/en unknown
- 1979-05-25 NL NL7904140A patent/NL7904140A/en not_active Application Discontinuation
- 1979-05-25 JP JP6550379A patent/JPS54154512A/en active Pending
- 1979-08-08 IE IE1001/79A patent/IE48124B1/en not_active IP Right Cessation
- 1979-08-08 IE IE1002/79A patent/IE48125B1/en not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
CH637295A5 (en) | 1983-07-29 |
LU81318A1 (en) | 1979-09-11 |
NL7904140A (en) | 1979-11-27 |
US4254147A (en) | 1981-03-03 |
BE876561A (en) | 1979-09-17 |
JPS54154512A (en) | 1979-12-05 |
IE791001L (en) | 1979-11-25 |
DK213879A (en) | 1979-11-26 |
NL7904141A (en) | 1979-11-27 |
GB2021410A (en) | 1979-12-05 |
GB2021414B (en) | 1982-10-13 |
DK213979A (en) | 1979-11-26 |
FR2426463B1 (en) | 1982-10-15 |
BE876560A (en) | 1979-09-17 |
FR2426462A1 (en) | 1979-12-21 |
IL57372A0 (en) | 1979-09-30 |
LU81316A1 (en) | 1979-09-11 |
CA1139224A (en) | 1983-01-11 |
CA1132907A (en) | 1982-10-05 |
IE48124B1 (en) | 1984-10-03 |
GB2021410B (en) | 1982-12-22 |
GB2021414A (en) | 1979-12-05 |
CH637296A5 (en) | 1983-07-29 |
JPS54154513A (en) | 1979-12-05 |
DE2921331A1 (en) | 1979-11-29 |
DE2921312A1 (en) | 1979-12-06 |
IE791002L (en) | 1979-11-25 |
IT1156769B (en) | 1987-02-04 |
IT7849534A0 (en) | 1978-05-25 |
IE48125B1 (en) | 1984-10-03 |
IL57373A0 (en) | 1979-09-30 |
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