FR2422663A1 - Nouvelle preparation de l'homoeburnamine - Google Patents
Nouvelle preparation de l'homoeburnamineInfo
- Publication number
- FR2422663A1 FR2422663A1 FR7833174A FR7833174A FR2422663A1 FR 2422663 A1 FR2422663 A1 FR 2422663A1 FR 7833174 A FR7833174 A FR 7833174A FR 7833174 A FR7833174 A FR 7833174A FR 2422663 A1 FR2422663 A1 FR 2422663A1
- Authority
- FR
- France
- Prior art keywords
- prepn
- acrolein
- ethyl
- eburnamine
- indolo
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/22—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed systems contains four or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Les isomères (+) ou (-) de l'homoéburnamine sont préparés en faisant réagir le sel de l'éthyle-1-hexahydro-1,2,3,4,6,7-indolo-(2,3-a) quinolozidinium sur l'acroléine pour donner un sel de déhydro-3,4-homoéburnamine intermédiaire, et en réduisant l'intermédiaire pour obtenir l'homoéburnamine appropriée. L'isomère obtenue dépend de l'agent de réduction utilisé. Les produits sont utiles en tant qu'intermédiaires dans la synthèse de la vincamine ( +- ) et de ses isomères.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB4920077 | 1977-11-25 |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2422663A1 true FR2422663A1 (fr) | 1979-11-09 |
FR2422663B1 FR2422663B1 (fr) | 1982-02-19 |
Family
ID=10451533
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7833174A Granted FR2422663A1 (fr) | 1977-11-25 | 1978-11-24 | Nouvelle preparation de l'homoeburnamine |
Country Status (1)
Country | Link |
---|---|
FR (1) | FR2422663A1 (fr) |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1173265A (en) * | 1967-06-02 | 1969-12-03 | Miles Lab | Hexahydro- and Octahydro-1,12-Trimethyleneindolo[2,3-a]-Quinolizines |
FR2363569A1 (fr) * | 1976-09-03 | 1978-03-31 | Buzas Andre | Nouveaux stereoisomeres d'esters de l'acide dihydro-apovincaminique |
-
1978
- 1978-11-24 FR FR7833174A patent/FR2422663A1/fr active Granted
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1173265A (en) * | 1967-06-02 | 1969-12-03 | Miles Lab | Hexahydro- and Octahydro-1,12-Trimethyleneindolo[2,3-a]-Quinolizines |
FR2363569A1 (fr) * | 1976-09-03 | 1978-03-31 | Buzas Andre | Nouveaux stereoisomeres d'esters de l'acide dihydro-apovincaminique |
Non-Patent Citations (1)
Title |
---|
EXBK/77 * |
Also Published As
Publication number | Publication date |
---|---|
FR2422663B1 (fr) | 1982-02-19 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ST | Notification of lapse |