FR2413702A1 - Gradient proportioning for liquid chromatography system - by one pump and program controlled metering valves - Google Patents

Gradient proportioning for liquid chromatography system - by one pump and program controlled metering valves

Info

Publication number
FR2413702A1
FR2413702A1 FR7814186A FR7814186A FR2413702A1 FR 2413702 A1 FR2413702 A1 FR 2413702A1 FR 7814186 A FR7814186 A FR 7814186A FR 7814186 A FR7814186 A FR 7814186A FR 2413702 A1 FR2413702 A1 FR 2413702A1
Authority
FR
France
Prior art keywords
liquid chromatography
chromatography system
pump
program controlled
metering valves
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7814186A
Other languages
French (fr)
Other versions
FR2413702B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Varian Medical Systems Inc
Original Assignee
Varian Associates Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Varian Associates Inc filed Critical Varian Associates Inc
Publication of FR2413702A1 publication Critical patent/FR2413702A1/en
Application granted granted Critical
Publication of FR2413702B1 publication Critical patent/FR2413702B1/fr
Granted legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
    • B01D15/16—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to the conditioning of the fluid carrier
    • B01D15/166—Fluid composition conditioning, e.g. gradient
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/26—Conditioning of the fluid carrier; Flow patterns
    • G01N30/28—Control of physical parameters of the fluid carrier
    • G01N30/36—Control of physical parameters of the fluid carrier in high pressure liquid systems
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/26—Conditioning of the fluid carrier; Flow patterns
    • G01N30/28—Control of physical parameters of the fluid carrier
    • G01N30/32—Control of physical parameters of the fluid carrier of pressure or speed
    • G01N2030/326—Control of physical parameters of the fluid carrier of pressure or speed pumps
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/26—Conditioning of the fluid carrier; Flow patterns
    • G01N30/28—Control of physical parameters of the fluid carrier
    • G01N30/34—Control of physical parameters of the fluid carrier of fluid composition, e.g. gradient

Landscapes

  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Reciprocating Pumps (AREA)

Abstract

Process to create a gradient proportioning of several solvent components in a liquid chromatography system required only one reciprocating pump. The introduced pumping cycle includes several filling strokes. During some (one) of all strokes in the pumping cycle, a selected concn. distribution of >1 solvent component is accepted.
FR7814186A 1977-05-13 1978-05-12 Gradient proportioning for liquid chromatography system - by one pump and program controlled metering valves Granted FR2413702A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US79678277A 1977-05-13 1977-05-13

Publications (2)

Publication Number Publication Date
FR2413702A1 true FR2413702A1 (en) 1979-07-27
FR2413702B1 FR2413702B1 (en) 1984-01-06

Family

ID=25169049

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7814186A Granted FR2413702A1 (en) 1977-05-13 1978-05-12 Gradient proportioning for liquid chromatography system - by one pump and program controlled metering valves

Country Status (3)

Country Link
JP (1) JPS53141698A (en)
DE (1) DE2821005A1 (en)
FR (1) FR2413702A1 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2476501B1 (en) * 1980-02-21 1988-07-08 Toray Industries PROCESS AND APPARATUS FOR PREPARING A PRECISION DOSE FLUID MIXTURE
DE3238026A1 (en) * 1982-10-11 1983-03-24 Andreas 1000 Berlin Kage Method of degassing, purifying and reproducibly mixing liquids in the field of chromatography
DE3401059A1 (en) * 1984-01-13 1985-07-18 Gesellschaft für Biotechnologische Forschung mbH (GBF), 3300 Braunschweig ARRANGEMENT FOR CHEMICAL ANALYSIS AND SYNTHESIS
EP0231566A1 (en) * 1986-02-05 1987-08-12 Magnetopulse Ltd. Improvements in and relating to liquid chromatography
DE4134494A1 (en) * 1991-10-18 1993-04-22 Wagner Wilhelm Wiwa Delivery and dosing assembly for static mixer for e.g. paint - has pressurised supply with separate drives for each component
FR2836185B1 (en) * 2002-02-21 2004-10-15 Inst Francais Du Petrole METHOD AND SYSTEM FOR THE FINE DOSING OF INJECTED FLUIDS IN A PUMP INSATLLATION
DE102009020412A1 (en) * 2009-05-08 2010-11-18 Lewa Gmbh Method and device for mixing fluids
DE102010034585B4 (en) * 2010-08-17 2016-04-07 Lewa Gmbh Apparatus for carrying out chromatography
DE102017117584B4 (en) * 2017-08-03 2019-05-29 Dürr Systems Ag Mixing plant and corresponding mixing process

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3799396A (en) * 1972-06-26 1974-03-26 Du Pont Method for producing a gradient elution
US4004884A (en) * 1976-07-02 1977-01-25 Hoffmann-La Roche Inc. Time division metering system
US4018685A (en) * 1975-10-24 1977-04-19 Union Oil Company Of California Automatic liquid mixing device

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3985021A (en) * 1975-11-10 1976-10-12 Varian Associates High performance liquid chromatography system
US3985019A (en) * 1975-11-10 1976-10-12 Boehme Detlef R Liquid chromatography system with solvent proportioning

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3799396A (en) * 1972-06-26 1974-03-26 Du Pont Method for producing a gradient elution
US4018685A (en) * 1975-10-24 1977-04-19 Union Oil Company Of California Automatic liquid mixing device
US4004884A (en) * 1976-07-02 1977-01-25 Hoffmann-La Roche Inc. Time division metering system

Also Published As

Publication number Publication date
FR2413702B1 (en) 1984-01-06
JPS53141698A (en) 1978-12-09
DE2821005A1 (en) 1978-11-23
DE2821005C2 (en) 1987-06-25

Similar Documents

Publication Publication Date Title
BR9105948A (en) PROCESS AND APPLIANCE FOR MIXING A LIQUID AND A MEDICINE
FR2413702A1 (en) Gradient proportioning for liquid chromatography system - by one pump and program controlled metering valves
JPS5438324B2 (en)
GB1477581A (en) High pressure sample injection apparatus and method
EP0181437A3 (en) Process and apparatus for chemical analysis by liquid cromatography
GB1534540A (en) Automatic system for high pressure liquid chromatography
EP0260760A3 (en) Liquid chromatograph
GB991766A (en) Improvements in or relating to apparatus for measuring liquids
GB1051309A (en)
DE3170430D1 (en) A method of operating liquid metering apparatus
ES428884A2 (en) Improvements in washing machines. (Machine-translation by Google Translate, not legally binding)
GB1535853A (en) Liquid metering pumps
ES428681A1 (en) Liquid fuel pumping apparatus
JPS6426150A (en) Sample distribution system for liquid chromatography
JPS5248107A (en) Plunger pump equipped with diaphragms
JPS5211229A (en) Apparatus for applying liquid to cloth
SE8003645L (en) SET AND DEVICE BY LIQUID CHROMATOGRAPHY
FR2273177A1 (en) Gas compression method and process plant - has gas-liquid mix preparatory, circulating pump and gas separator unit
JPS51137119A (en) Method to prevent liquid pulsation
FR2042718A2 (en) Dosing and mixing of polyurethane components
GB1242061A (en) Process and apparatus for impregnating timber
GB1055951A (en) Apparatus for metering viscous liquids,preferably viscous core binders for foundry purposes
GB982304A (en) Chromatography apparatus
GB1004292A (en) Improvements in or relating to metering pumps for viscous material containing solid sectile bodies
FR2328066A1 (en) Dyeing fibres in form of a compressed bale - held against an outlet in a dye chamber through which dye is circulated (SW 16.5.77)