FR2408614A1 - NEW CEPHALOSPORINS, THEIR PROCESS FOR PREPARATION AND PHARMACEUTICAL COMPOSITION CONTAINING THEM - Google Patents

NEW CEPHALOSPORINS, THEIR PROCESS FOR PREPARATION AND PHARMACEUTICAL COMPOSITION CONTAINING THEM

Info

Publication number
FR2408614A1
FR2408614A1 FR7730383A FR7730383A FR2408614A1 FR 2408614 A1 FR2408614 A1 FR 2408614A1 FR 7730383 A FR7730383 A FR 7730383A FR 7730383 A FR7730383 A FR 7730383A FR 2408614 A1 FR2408614 A1 FR 2408614A1
Authority
FR
France
Prior art keywords
preparation
pharmaceutical composition
composition containing
new cephalosporins
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7730383A
Other languages
French (fr)
Other versions
FR2408614B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Co
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/784,885 external-priority patent/US4082912A/en
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of FR2408614A1 publication Critical patent/FR2408614A1/en
Application granted granted Critical
Publication of FR2408614B1 publication Critical patent/FR2408614B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • C07D217/24—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

L'INVENTION CONCERNE DE NOUVEAUX ACIDES AMINO-3-(2-CARBOXYALKYL-2,3-DIHYDRO-S-TRIAZOLO 4,3-BPYRIDAZINE-3-ONE-6-YLTHIOMETHYL)-3-CEPHEM-4-CARBOXYLIQUES, LEURS SELS ET LEURS ESTERS AISEMENT HYDROLYSES DU GROUPE 4-CARBOXYLE. ELLE CONCERNE EGALEMENT LA SYNTHESE DE CES COMPOSES. LES COMPOSES DE L'INVENTION SONT DE PUISSANTS AGENTS ANTIBACTERIENS, QUI ONT UNE BONNE SOLUBILITE DANS L'EAU.THE INVENTION CONCERNS NEW AMINO-3- (2-CARBOXYALKYL-2,3-DIHYDRO-S-TRIAZOLO 4,3-BPYRIDAZINE-3-ONE-6-YLTHIOMETHYL) -3-CEPHEM-4-CARBOXYLIC ACIDS, THEIR SALTS AND THEIR EASILY HYDROLYZED ESTERS OF THE 4-CARBOXYL GROUP. IT ALSO CONCERNS THE SYNTHESIS OF THESE COMPOUNDS. THE COMPOUNDS OF THE INVENTION ARE POWERFUL ANTIBACTERIAL AGENTS, WHICH HAVE GOOD SOLUBILITY IN WATER.

FR7730383A 1977-04-05 1977-10-10 NEW CEPHALOSPORINS, THEIR PROCESS FOR PREPARATION AND PHARMACEUTICAL COMPOSITION CONTAINING THEM Granted FR2408614A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/784,885 US4082912A (en) 1976-06-30 1977-04-05 Certain 7-acylamido-3-(2-carboxyalkyl-2,3-dihydro-s-triazolo[4,3-b]pyridazin-3-on-6-ylmethyl)-3-cephem-4-carboxylic acids their salts and easily hydrolyzed esters

Publications (2)

Publication Number Publication Date
FR2408614A1 true FR2408614A1 (en) 1979-06-08
FR2408614B1 FR2408614B1 (en) 1980-12-05

Family

ID=25133827

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7730383A Granted FR2408614A1 (en) 1977-04-05 1977-10-10 NEW CEPHALOSPORINS, THEIR PROCESS FOR PREPARATION AND PHARMACEUTICAL COMPOSITION CONTAINING THEM

Country Status (17)

Country Link
JP (1) JPS53124290A (en)
AU (1) AU517919B2 (en)
BE (1) BE859774A (en)
CA (1) CA1113455A (en)
CH (1) CH627184A5 (en)
DE (1) DE2807847A1 (en)
DK (1) DK145497C (en)
FI (1) FI60869C (en)
FR (1) FR2408614A1 (en)
GB (1) GB1572201A (en)
GR (1) GR73550B (en)
IE (1) IE45613B1 (en)
LU (1) LU78323A1 (en)
NL (1) NL7711644A (en)
SE (1) SE425491B (en)
YU (1) YU247977A (en)
ZA (1) ZA775781B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3000377A1 (en) * 1980-01-07 1981-07-09 Boehringer Mannheim Gmbh, 6800 Mannheim NEW SULPHONAMIDES, METHOD FOR THE PRODUCTION THEREOF AND MEDICINAL PRODUCTS CONTAINING THESE COMPOUNDS
CN114940665B (en) * 2022-06-10 2024-05-07 河南省科学院高新技术研究中心 Benzisothiazolinone compound serving as bactericide and preparation method thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3907786A (en) * 1973-09-04 1975-09-23 Bristol Myers Co 7-{8 {60 -(2-aminomethyl-1,4-cyclohexadienyl)acetamido{9 -3-heterocyclic-thiomethyl-3-cephem-4-carboxylic acids and salts
US3946000A (en) * 1973-10-31 1976-03-23 Bristol-Myers Company 7-[α-(2-Aminomethyl-1-cyclohexenyl)-acetamido]-3-heterocyclic thiomethyl-3-cephem-4-carboxylic acids

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3907786A (en) * 1973-09-04 1975-09-23 Bristol Myers Co 7-{8 {60 -(2-aminomethyl-1,4-cyclohexadienyl)acetamido{9 -3-heterocyclic-thiomethyl-3-cephem-4-carboxylic acids and salts
US3946000A (en) * 1973-10-31 1976-03-23 Bristol-Myers Company 7-[α-(2-Aminomethyl-1-cyclohexenyl)-acetamido]-3-heterocyclic thiomethyl-3-cephem-4-carboxylic acids

Also Published As

Publication number Publication date
DE2807847A1 (en) 1978-10-19
FI60869B (en) 1981-12-31
AU2932877A (en) 1979-04-12
NL7711644A (en) 1978-10-09
SE7710823L (en) 1978-10-06
AU517919B2 (en) 1981-09-03
ZA775781B (en) 1978-08-30
DK145497B (en) 1982-11-29
BE859774A (en) 1978-04-14
FI772860A (en) 1978-10-06
FI60869C (en) 1982-04-13
FR2408614B1 (en) 1980-12-05
DK429577A (en) 1978-10-06
DK145497C (en) 1983-05-02
YU247977A (en) 1982-10-31
GR73550B (en) 1984-03-13
CA1113455A (en) 1981-12-01
LU78323A1 (en) 1978-06-12
SE425491B (en) 1982-10-04
IE45613L (en) 1978-10-05
CH627184A5 (en) 1981-12-31
JPS53124290A (en) 1978-10-30
IE45613B1 (en) 1982-10-06
GB1572201A (en) 1980-07-23

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Legal Events

Date Code Title Description
ST Notification of lapse