FR2401897A1 - B-dicetones substituees, leur preparation et leur utilisation comme agents anti-viraux - Google Patents
B-dicetones substituees, leur preparation et leur utilisation comme agents anti-virauxInfo
- Publication number
- FR2401897A1 FR2401897A1 FR7825020A FR7825020A FR2401897A1 FR 2401897 A1 FR2401897 A1 FR 2401897A1 FR 7825020 A FR7825020 A FR 7825020A FR 7825020 A FR7825020 A FR 7825020A FR 2401897 A1 FR2401897 A1 FR 2401897A1
- Authority
- FR
- France
- Prior art keywords
- substituted
- dicetones
- preparation
- aliphatic
- viral agents
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000003443 antiviral agent Substances 0.000 title 1
- 125000001931 aliphatic group Chemical group 0.000 abstract 2
- 229910052783 alkali metal Inorganic materials 0.000 abstract 1
- -1 alkali metal salt Chemical class 0.000 abstract 1
- 230000000840 anti-viral effect Effects 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000004122 cyclic group Chemical group 0.000 abstract 1
- 125000000113 cyclohexyl group Chemical group [H]C1([H])C([H])([H])C([H])([H])C([H])(*)C([H])([H])C1([H])[H] 0.000 abstract 1
- 125000002541 furyl group Chemical group 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/40—Esters thereof
- C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
- C07F9/4056—Esters of arylalkanephosphonic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C17/00—Preparation of halogenated hydrocarbons
- C07C17/093—Preparation of halogenated hydrocarbons by replacement by halogens
- C07C17/10—Preparation of halogenated hydrocarbons by replacement by halogens of hydrogen atoms
- C07C17/14—Preparation of halogenated hydrocarbons by replacement by halogens of hydrogen atoms in the side-chain of aromatic compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C41/00—Preparation of ethers; Preparation of compounds having groups, groups or groups
- C07C41/01—Preparation of ethers
- C07C41/18—Preparation of ethers by reactions not forming ether-oxygen bonds
- C07C41/22—Preparation of ethers by reactions not forming ether-oxygen bonds by introduction of halogens; by substitution of halogen atoms by other halogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C41/00—Preparation of ethers; Preparation of compounds having groups, groups or groups
- C07C41/01—Preparation of ethers
- C07C41/18—Preparation of ethers by reactions not forming ether-oxygen bonds
- C07C41/26—Preparation of ethers by reactions not forming ether-oxygen bonds by introduction of hydroxy or O-metal groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C41/00—Preparation of ethers; Preparation of compounds having groups, groups or groups
- C07C41/01—Preparation of ethers
- C07C41/18—Preparation of ethers by reactions not forming ether-oxygen bonds
- C07C41/30—Preparation of ethers by reactions not forming ether-oxygen bonds by increasing the number of carbon atoms, e.g. by oligomerisation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
- C07C45/673—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by change of size of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
- C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/20—Unsaturated compounds containing keto groups bound to acyclic carbon atoms
- C07C49/225—Unsaturated compounds containing keto groups bound to acyclic carbon atoms containing six-membered aromatic rings and other rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/20—Unsaturated compounds containing keto groups bound to acyclic carbon atoms
- C07C49/227—Unsaturated compounds containing keto groups bound to acyclic carbon atoms containing halogen
- C07C49/233—Unsaturated compounds containing keto groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/20—Unsaturated compounds containing keto groups bound to acyclic carbon atoms
- C07C49/24—Unsaturated compounds containing keto groups bound to acyclic carbon atoms containing hydroxy groups
- C07C49/245—Unsaturated compounds containing keto groups bound to acyclic carbon atoms containing hydroxy groups containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/20—Unsaturated compounds containing keto groups bound to acyclic carbon atoms
- C07C49/24—Unsaturated compounds containing keto groups bound to acyclic carbon atoms containing hydroxy groups
- C07C49/245—Unsaturated compounds containing keto groups bound to acyclic carbon atoms containing hydroxy groups containing six-membered aromatic rings
- C07C49/248—Unsaturated compounds containing keto groups bound to acyclic carbon atoms containing hydroxy groups containing six-membered aromatic rings having unsaturation outside the aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/20—Unsaturated compounds containing keto groups bound to acyclic carbon atoms
- C07C49/255—Unsaturated compounds containing keto groups bound to acyclic carbon atoms containing ether groups, groups, groups, or groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- Virology (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Communicable Diseases (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Furan Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
L'invention concerne des beta -dicétones substituées sur l'atome de carbone compris entre les deux groupements carbonyle par un groupement aryle aliphatique dont la chaîne aliphatique est interrompue par un groupement cyclique (phényle éventuellement substitué, cyclohexyle ou furyle), que l'on prépare en faisant réagir l'halogénure aryl-aliphatique approprié avec un sel de métal alcalin d'une beta -dicétone. Les composés ainsi obtenus ont une activité antivirale.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US05/830,470 US4153719A (en) | 1977-09-06 | 1977-09-06 | Aromatic diketones |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2401897A1 true FR2401897A1 (fr) | 1979-03-30 |
FR2401897B1 FR2401897B1 (fr) | 1981-11-27 |
Family
ID=25257068
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7825020A Granted FR2401897A1 (fr) | 1977-09-06 | 1978-08-30 | B-dicetones substituees, leur preparation et leur utilisation comme agents anti-viraux |
Country Status (14)
Country | Link |
---|---|
US (1) | US4153719A (fr) |
JP (1) | JPS5452048A (fr) |
AU (1) | AU3918778A (fr) |
BE (1) | BE870103A (fr) |
CA (1) | CA1089864A (fr) |
DE (1) | DE2838276A1 (fr) |
DK (1) | DK365878A (fr) |
FR (1) | FR2401897A1 (fr) |
GB (1) | GB2004542B (fr) |
IT (1) | IT1106285B (fr) |
LU (1) | LU80183A1 (fr) |
NL (1) | NL7808946A (fr) |
NZ (1) | NZ188203A (fr) |
SE (1) | SE7809350L (fr) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4256659A (en) * | 1977-03-28 | 1981-03-17 | Union Carbide Corporation | Method of preparing 2-aryl-1,3-cyclohexanedione compounds |
LU86387A1 (fr) * | 1986-04-04 | 1987-12-07 | Oreal | Composes aromatiques,leur procede de preparation et leur utilisation en medicine humaine et veterinaire et en cosmetique |
IL91382A (en) * | 1988-09-01 | 1995-06-29 | Orion Yhtymae Oy | Dicitons are converted into alkanyl or ethylmethylene, through their preparation and pharmaceutical preparations containing them |
US5185370A (en) * | 1988-09-01 | 1993-02-09 | Orion-Yhtyma Oy | Substituted β-diketones and their use |
TW527186B (en) * | 1996-03-19 | 2003-04-11 | Janssen Pharmaceutica Nv | Fused imidazole derivatives as multidrug resistance modulators |
US20080253967A1 (en) * | 2007-04-13 | 2008-10-16 | Kung Hank F | Halo-Stilbene Derivatives And Their Use For Binding And Imaging Of Amyloid Plaques |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR1564677A (fr) * | 1967-02-17 | 1969-03-17 | ||
FR2189068A1 (fr) * | 1972-06-22 | 1974-01-25 | Sterling Drug Inc |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3917718A (en) * | 1972-06-22 | 1975-11-04 | Sterling Drug Inc | Cyclopropyl carbinol derivatives |
US3878200A (en) * | 1973-01-17 | 1975-04-15 | Sterling Drug Inc | Aryl substituted tertiary carbinols |
US4082807A (en) * | 1973-07-23 | 1978-04-04 | Hoechst Aktiengesellschaft | Process for the manufacture of aromatic 1,3-diketones |
DE2412582A1 (de) * | 1974-03-15 | 1975-10-02 | Thiemann Chem Pharm Fab | 11h,12h- eckige klammer auf 1 eckige klammer zu benzopyrano eckige klammer auf 2,3-b eckige klammer zu eckige klammer auf 1 eckige klammer zu benzopyran-11,12-dion- und 11h,12h- eckige klammer auf 1 eckige klammer zu benzothiopyrano eckige klammer auf 2,3-b eckige klammer zu eckige klammer auf 1 eckige klammer zu benzothiopyran-11,12-dion-verbindungen |
-
1977
- 1977-09-06 US US05/830,470 patent/US4153719A/en not_active Expired - Lifetime
-
1978
- 1978-08-15 CA CA309,417A patent/CA1089864A/fr not_active Expired
- 1978-08-18 DK DK365878A patent/DK365878A/da not_active Application Discontinuation
- 1978-08-21 NZ NZ188203A patent/NZ188203A/xx unknown
- 1978-08-23 AU AU39187/78A patent/AU3918778A/en active Pending
- 1978-08-24 GB GB7834519A patent/GB2004542B/en not_active Expired
- 1978-08-30 FR FR7825020A patent/FR2401897A1/fr active Granted
- 1978-08-31 NL NL7808946A patent/NL7808946A/xx not_active Application Discontinuation
- 1978-08-31 BE BE1009037A patent/BE870103A/fr unknown
- 1978-08-31 LU LU80183A patent/LU80183A1/fr unknown
- 1978-09-01 DE DE19782838276 patent/DE2838276A1/de not_active Withdrawn
- 1978-09-01 JP JP10742578A patent/JPS5452048A/ja active Pending
- 1978-09-01 IT IT50935/78A patent/IT1106285B/it active
- 1978-09-05 SE SE7809350A patent/SE7809350L/xx unknown
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR1564677A (fr) * | 1967-02-17 | 1969-03-17 | ||
FR2189068A1 (fr) * | 1972-06-22 | 1974-01-25 | Sterling Drug Inc |
Non-Patent Citations (1)
Title |
---|
EXBK/77 * |
Also Published As
Publication number | Publication date |
---|---|
LU80183A1 (fr) | 1979-05-15 |
GB2004542B (en) | 1982-03-17 |
NZ188203A (en) | 1980-03-05 |
IT1106285B (it) | 1985-11-11 |
DK365878A (da) | 1979-03-07 |
JPS5452048A (en) | 1979-04-24 |
FR2401897B1 (fr) | 1981-11-27 |
SE7809350L (sv) | 1979-03-07 |
GB2004542A (en) | 1979-04-04 |
AU3918778A (en) | 1980-02-28 |
CA1089864A (fr) | 1980-11-18 |
IT7850935A0 (it) | 1978-09-01 |
NL7808946A (nl) | 1979-03-08 |
DE2838276A1 (de) | 1979-03-15 |
BE870103A (fr) | 1979-02-28 |
US4153719A (en) | 1979-05-08 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ES8206488A1 (es) | Un procedimiento para preparar compuestos de purina y piri- midina | |
FR2360553A1 (fr) | Compose cyclique ethylenique, procede de preparation de ce compose et utilisation de ce compose pour preparer un ester methylenemalonique | |
FR2416225A1 (fr) | Derives de la 4-amino-3 sulfamido-pyridine, leur procede de preparation et leur application comme diuretiques | |
FR2382439A1 (fr) | Procede d'obtention de phenates metalliques sulfures | |
FR2401897A1 (fr) | B-dicetones substituees, leur preparation et leur utilisation comme agents anti-viraux | |
IT1229656B (it) | Composizioni lubrificanti contenenti ditiofosfati non metallici. | |
ES463234A1 (es) | Procedimiento para preparar compuestos de aril azufre. | |
FR2383185A1 (fr) | ||
FR2387989A1 (fr) | Analogues des alcaloides de l'ergot | |
ES8801196A1 (es) | Procedimiento para la obtencion de i-benzoil-3-aril-ureas | |
FR2358141A1 (fr) | Nouveaux anesthesiques locaux | |
FR2429229A1 (fr) | Procede pour preparer des polyolefines | |
FR2381746A1 (fr) | Nouveaux derives encephaliniques a la methionine | |
ES8304103A1 (es) | Un procedimientpo para la preparacion de nuevos derivados de carbamoiloxiisoxazol. | |
GB1421561A (en) | Pesticidal thiophosphoric acid esters | |
FR2380271A1 (fr) | Acides halogene-benzofuranone-carboxyliques utiles comme intermediaires de synthese | |
GB1531053A (en) | Preparation of 2,6-dialkyl-4-hydroxyl-phenylsulphenyl chlorides | |
FR2377378A1 (fr) | Nouvelles amidines | |
FR2398738A1 (fr) | Preparation de benzoylurees | |
GB1341155A (en) | Dithiophosphoric acid esters having insecticidal acaricidal and nematocidal properties | |
GB1422876A (en) | Biocidal phosphorothioates and phosphorodithioates | |
ES377643A1 (es) | Procedimiento de obtencion de composiciones fungicidas, in-secticidas y acaricidas. | |
ATE23158T1 (de) | Hexahydrodioxopyrimidine, ihre herstellung und verwendung. | |
GB1304325A (fr) | ||
GB1437364A (en) | Pesticidal phosphorus-containing triazole derivatives |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
ST | Notification of lapse |