FR2395262A1 - NEW QUINOLEINIC ACIDS USEFUL IN PARTICULAR AS ANTI-INFLAMMATORY AND THEIR PREPARATION PROCESS - Google Patents

NEW QUINOLEINIC ACIDS USEFUL IN PARTICULAR AS ANTI-INFLAMMATORY AND THEIR PREPARATION PROCESS

Info

Publication number
FR2395262A1
FR2395262A1 FR7818625A FR7818625A FR2395262A1 FR 2395262 A1 FR2395262 A1 FR 2395262A1 FR 7818625 A FR7818625 A FR 7818625A FR 7818625 A FR7818625 A FR 7818625A FR 2395262 A1 FR2395262 A1 FR 2395262A1
Authority
FR
France
Prior art keywords
quinoleinic
inflammatory
new
preparation process
acids useful
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7818625A
Other languages
French (fr)
Other versions
FR2395262B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SIMES Societa Italiana Medicinali e Sintetici SpA
Original Assignee
SIMES Societa Italiana Medicinali e Sintetici SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SIMES Societa Italiana Medicinali e Sintetici SpA filed Critical SIMES Societa Italiana Medicinali e Sintetici SpA
Publication of FR2395262A1 publication Critical patent/FR2395262A1/en
Application granted granted Critical
Publication of FR2395262B1 publication Critical patent/FR2395262B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/22—Oxygen atoms attached in position 2 or 4
    • C07D215/227—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/18—Halogen atoms or nitro radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/22—Oxygen atoms attached in position 2 or 4
    • C07D215/233—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/58—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems with hetero atoms directly attached to the ring nitrogen atom
    • C07D215/60—N-oxides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Quinoline Compounds (AREA)

Abstract

Les composés selon l'invention répondent à la formule générale :The compounds according to the invention correspond to the general formula:

FR7818625A 1977-06-22 1978-06-21 NEW QUINOLEINIC ACIDS USEFUL IN PARTICULAR AS ANTI-INFLAMMATORY AND THEIR PREPARATION PROCESS Granted FR2395262A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH768277A CH628892A5 (en) 1977-06-22 1977-06-22 PROCEDURE FOR THE PREPARATION OF QUINOLINIC ACIDS FOR ANTI-INFLAMMATORY ACTIVITY.

Publications (2)

Publication Number Publication Date
FR2395262A1 true FR2395262A1 (en) 1979-01-19
FR2395262B1 FR2395262B1 (en) 1981-06-26

Family

ID=4328943

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7818625A Granted FR2395262A1 (en) 1977-06-22 1978-06-21 NEW QUINOLEINIC ACIDS USEFUL IN PARTICULAR AS ANTI-INFLAMMATORY AND THEIR PREPARATION PROCESS

Country Status (7)

Country Link
JP (1) JPS549285A (en)
BE (1) BE868359A (en)
CH (1) CH628892A5 (en)
DE (1) DE2827472A1 (en)
FR (1) FR2395262A1 (en)
GB (1) GB2001959A (en)
IT (1) IT1192259B (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0083222A1 (en) * 1981-12-29 1983-07-06 Nippon Zoki Pharmaceutical Co. Ltd. New quinolylacetic acid compounds and pharmaceutical compositions containing them
EP0370317A1 (en) * 1988-11-22 1990-05-30 Bayer Ag Process for the preparation of substituted 2-chloropyridines

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3991061A (en) * 1975-07-16 1976-11-09 G. D. Searle & Co. Azanaphthaleneacetic acid derivatives

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3991061A (en) * 1975-07-16 1976-11-09 G. D. Searle & Co. Azanaphthaleneacetic acid derivatives

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0083222A1 (en) * 1981-12-29 1983-07-06 Nippon Zoki Pharmaceutical Co. Ltd. New quinolylacetic acid compounds and pharmaceutical compositions containing them
EP0370317A1 (en) * 1988-11-22 1990-05-30 Bayer Ag Process for the preparation of substituted 2-chloropyridines
US5010201A (en) * 1988-11-22 1991-04-23 Bayer Aktiengesellschaft Process for the preparation of substituted 2-chloropyridines

Also Published As

Publication number Publication date
JPS549285A (en) 1979-01-24
IT1192259B (en) 1988-03-31
CH628892A5 (en) 1982-03-31
IT7823904A0 (en) 1978-05-26
FR2395262B1 (en) 1981-06-26
DE2827472A1 (en) 1979-01-11
BE868359A (en) 1978-10-16
GB2001959A (en) 1979-02-14

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Legal Events

Date Code Title Description
ST Notification of lapse