FR2395027A2 - S, S'-DECAMETHYLENE-1,10-MERCAPTAN DERIVATIVES USEFUL AS NORMOLIPIDEMATING MEDICINAL PRODUCTS - Google Patents

S, S'-DECAMETHYLENE-1,10-MERCAPTAN DERIVATIVES USEFUL AS NORMOLIPIDEMATING MEDICINAL PRODUCTS

Info

Publication number
FR2395027A2
FR2395027A2 FR7808374A FR7808374A FR2395027A2 FR 2395027 A2 FR2395027 A2 FR 2395027A2 FR 7808374 A FR7808374 A FR 7808374A FR 7808374 A FR7808374 A FR 7808374A FR 2395027 A2 FR2395027 A2 FR 2395027A2
Authority
FR
France
Prior art keywords
decamethylene
normolipidemating
medicinal products
derivatives useful
mercaptan derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7808374A
Other languages
French (fr)
Other versions
FR2395027B2 (en
Inventor
Louis Lafon
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cephalon France SAS
Original Assignee
Laboratoire L Lafon SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratoire L Lafon SA filed Critical Laboratoire L Lafon SA
Publication of FR2395027A2 publication Critical patent/FR2395027A2/en
Application granted granted Critical
Publication of FR2395027B2 publication Critical patent/FR2395027B2/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C335/00—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C335/30—Isothioureas
    • C07C335/32—Isothioureas having sulfur atoms of isothiourea groups bound to acyclic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups

Abstract

La présente addition concerne l'utilisation en thérapeutique des dérivés de décaméthylène-1,10-mercaptan de formule : (CH2 )10 Ø-S-Aõ2 dans laquelle A est C( = NH)NH2 , CH(CO 2 H)CH2 CO2 H, CH(CO2 R)CH2 CO2 R, CH2 CH2 CO2 H, CH2 CH2 CO2 R, CH2 CO2 R, CH(CH 3 )CO2 R, R étant un groupe alkyle inférieur en C1 -C3 ; et des sels de thiouronium correspondants lorsque A est C(= NH)NH2 .This addition relates to the therapeutic use of decamethylene-1,10-mercaptan derivatives of formula: (CH2) 10 Ø-S-Aõ2 in which A is C (= NH) NH2, CH (CO 2 H) CH2 CO2 H, CH (CO2 R) CH2 CO2 R, CH2 CH2 CO2 H, CH2 CH2 CO2 R, CH2 CO2 R, CH (CH 3) CO2 R, R being a lower alkyl group of C1 -C3; and corresponding thiouronium salts when A is C (= NH) NH2.

FR7808374A 1977-03-30 1978-03-22 S, S'-DECAMETHYLENE-1,10-MERCAPTAN DERIVATIVES USEFUL AS NORMOLIPIDEMATING MEDICINAL PRODUCTS Granted FR2395027A2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB13306/77A GB1603651A (en) 1977-03-30 1977-03-30 Normolipidemiant compositions

Publications (2)

Publication Number Publication Date
FR2395027A2 true FR2395027A2 (en) 1979-01-19
FR2395027B2 FR2395027B2 (en) 1982-01-15

Family

ID=10020566

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7808374A Granted FR2395027A2 (en) 1977-03-30 1978-03-22 S, S'-DECAMETHYLENE-1,10-MERCAPTAN DERIVATIVES USEFUL AS NORMOLIPIDEMATING MEDICINAL PRODUCTS

Country Status (8)

Country Link
JP (1) JPS53121718A (en)
BE (1) BE864998A (en)
CH (1) CH627368A5 (en)
DE (1) DE2810521A1 (en)
ES (1) ES468330A1 (en)
FR (1) FR2395027A2 (en)
GB (1) GB1603651A (en)
IT (1) IT1111621B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4446264A (en) * 1982-04-15 1984-05-01 The Goodyear Tire & Rubber Company Synergistic antioxidant mixtures
TW201627279A (en) * 2014-09-25 2016-08-01 巴地斯顏料化工廠 Liquid thioether carboxylic acid esters

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2038835A1 (en) * 1969-08-08 1971-02-18 Orsymonde 1,10-bis (carboxyalkylene thio) decanes
FR2288516A2 (en) * 1974-10-21 1976-05-21 Orsymonde Normolipaemic 1,10-bis-(carboxyalkylene-thio) - decanes - used to treat atherosclerosis and coronary artery troubles

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2038835A1 (en) * 1969-08-08 1971-02-18 Orsymonde 1,10-bis (carboxyalkylene thio) decanes
FR2288516A2 (en) * 1974-10-21 1976-05-21 Orsymonde Normolipaemic 1,10-bis-(carboxyalkylene-thio) - decanes - used to treat atherosclerosis and coronary artery troubles

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
CA1977 *

Also Published As

Publication number Publication date
ES468330A1 (en) 1979-10-01
DE2810521A1 (en) 1978-10-05
JPS53121718A (en) 1978-10-24
CH627368A5 (en) 1982-01-15
BE864998A (en) 1978-07-17
IT7867673A0 (en) 1978-03-24
IT1111621B (en) 1986-01-13
GB1603651A (en) 1981-11-25
FR2395027B2 (en) 1982-01-15

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