FR2394545A1 - Procede de fabrication de quininone et de quinidinone, intermediaires de synthese de la quinidine - Google Patents

Procede de fabrication de quininone et de quinidinone, intermediaires de synthese de la quinidine

Info

Publication number
FR2394545A1
FR2394545A1 FR7718398A FR7718398A FR2394545A1 FR 2394545 A1 FR2394545 A1 FR 2394545A1 FR 7718398 A FR7718398 A FR 7718398A FR 7718398 A FR7718398 A FR 7718398A FR 2394545 A1 FR2394545 A1 FR 2394545A1
Authority
FR
France
Prior art keywords
quinidinone
quininone
quinidine
manufacturing
synthesis intermediaries
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
FR7718398A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
DEVINTER SA
Original Assignee
DEVINTER SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by DEVINTER SA filed Critical DEVINTER SA
Priority to FR7718398A priority Critical patent/FR2394545A1/fr
Priority to US05/915,010 priority patent/US4174449A/en
Priority to US05/915,009 priority patent/US4175192A/en
Priority to DE7878400019T priority patent/DE2860032D1/de
Priority to EP78400019A priority patent/EP0000009B1/fr
Priority to EP19780400020 priority patent/EP0000302B1/fr
Priority to DE7878400020T priority patent/DE2860188D1/de
Priority to IE120378A priority patent/IE46996B1/en
Priority to IE120478A priority patent/IE46935B1/en
Publication of FR2394545A1 publication Critical patent/FR2394545A1/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
    • C07D453/04—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems having a quinolyl-4, a substituted quinolyl-4 or a alkylenedioxy-quinolyl-4 radical linked through only one carbon atom, attached in position 2, e.g. quinine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Quinoline Compounds (AREA)

Abstract

La présente invention concerne une oxydation de type Oppenhauer par un réactif dénommé Kétyl. Le Kétyl est obtenu par l'action directe d'un métal sur la cétone accepteur de la réaction classique d'Oppenhauer. La cétone en question est plus particulièrement une benzophénone ou une fluorénone. L'invention peut être appliquée à l'oxydation des alcaloïdes du quinquina et permet de transformer par exemple la quinine en quininone et quinidinone.
FR7718398A 1977-06-15 1977-06-15 Procede de fabrication de quininone et de quinidinone, intermediaires de synthese de la quinidine Withdrawn FR2394545A1 (fr)

Priority Applications (9)

Application Number Priority Date Filing Date Title
FR7718398A FR2394545A1 (fr) 1977-06-15 1977-06-15 Procede de fabrication de quininone et de quinidinone, intermediaires de synthese de la quinidine
US05/915,010 US4174449A (en) 1977-06-15 1978-06-13 Process for the reduction of quinidinone to quinidine
US05/915,009 US4175192A (en) 1977-06-15 1978-06-13 Process for preparing quininone
DE7878400019T DE2860032D1 (en) 1977-06-15 1978-06-14 Method for the oxidation of quinine to quininone and quinidinone.
EP78400019A EP0000009B1 (fr) 1977-06-15 1978-06-14 Procédé d'oxydation de quinine en quininone et quinidinone.
EP19780400020 EP0000302B1 (fr) 1977-06-15 1978-06-14 Nouveau procédé de préparation de la quinidine.
DE7878400020T DE2860188D1 (en) 1977-06-15 1978-06-14 Novel method for the preparation of quinidine.
IE120378A IE46996B1 (en) 1977-06-15 1978-06-15 Process for the preparation of quinidine
IE120478A IE46935B1 (en) 1977-06-15 1978-06-15 Process for the oxidation of quinine to quininone and quinidinone

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7718398A FR2394545A1 (fr) 1977-06-15 1977-06-15 Procede de fabrication de quininone et de quinidinone, intermediaires de synthese de la quinidine

Publications (1)

Publication Number Publication Date
FR2394545A1 true FR2394545A1 (fr) 1979-01-12

Family

ID=9192140

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7718398A Withdrawn FR2394545A1 (fr) 1977-06-15 1977-06-15 Procede de fabrication de quininone et de quinidinone, intermediaires de synthese de la quinidine

Country Status (4)

Country Link
EP (1) EP0000009B1 (fr)
DE (1) DE2860032D1 (fr)
FR (1) FR2394545A1 (fr)
IE (1) IE46935B1 (fr)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1165604B (de) * 1957-12-18 1964-03-19 Chininfabrik Braunschweig Buch Verfahren zur sterischen Umlagerung von Chinaalkaloiden
FR2332279A1 (fr) * 1975-11-19 1977-06-17 Nativelle Sa Ets Procede d'oxydation des alcaloides du quinquina
FR2332278A1 (fr) * 1975-11-19 1977-06-17 Nativelle Sa Ets Procede de transformation stereochimique des alcaloides du quinquina

Also Published As

Publication number Publication date
IE46935B1 (en) 1983-11-02
DE2860032D1 (en) 1980-11-13
EP0000009B1 (fr) 1980-07-23
EP0000009A1 (fr) 1978-12-20
IE781204L (en) 1978-12-15

Similar Documents

Publication Publication Date Title
DE3269579D1 (en) Preparation of alcohols from olefins having from 3 to 7 carbon atoms
BE848793A (fr) Procede de production de catalyseurs d'oxydation a base de molybdene et de bismuth et nouveaux produits ainsi obtenus,
FR2353856A1 (fr) Ruban destine a servir de support a une reaction par exemple chimique ou biochimique, et procede d'analyse le mettant en oeuvre
FR2343817A1 (fr) Procede de carburation ou de carbonitruration de pieces en acier
FR2416867A1 (fr) Procede de preparation d'une dispersion aqueuse d'oxyde de cerium
ATE71407T1 (de) Verfahren zur herstellung von peroxydase.
FR2456723A1 (fr) Procede de production d'esters carboxyliques
BR8703516A (pt) Processo de produzir corpo ceramico de auto-sustentacao e corpo ceramico assim obtido
FR2391987A1 (fr) Procede de fabrication d'acides organiques polycarboxyliques
FR2401186A1 (fr) Polyesters halogenes insatures, procede d'obtention et applications
FR2317372A1 (fr) Procede d'amelioration de la resistance a la corrosion de pieces en alliage de zirconium et pieces ainsi obtenues.
ES2039018T3 (es) Procedimiento para la fabricacion de alfa alquilacroleinas.
FR2443282A1 (fr) Procedes et composition catalytiques d'hydroformylation et d'hydrohydroxymethylation
NO875347D0 (no) Fremgangsmaate for fremstilling av organiske karbonater ved omestring.
FR2384846A1 (fr) Procede d'obtention de mutants de l'espece penicillium ayant une aptitude amelioree a la synthese de l'acide mycophenolique
FR2394545A1 (fr) Procede de fabrication de quininone et de quinidinone, intermediaires de synthese de la quinidine
FR2585593B1 (fr) Procede de fabrication d'un tube metallique et tube ainsi obtenu, notamment le traitement des gaines pour combustible nucleaire
FR2412368A1 (fr) Procede de fabrication d'un moule refractaire impregne de tungstene et moule obtenu
BG48570A3 (en) Ceramic body with polymer component and method for its manufacture
PT73314B (fr) Procede pour la fabrication de l'acide beta-hydroxybutyrique etde ses oligocondensats
BE782357A (fr) Procede de fabrication de catalyseurs d'oxydation et catalyseurs ainsi obtenus
FR2440350A1 (fr) Procede de fabrication de l'acide parahydroxymandelique racemique
FR2594435B1 (fr) Procede pour la fabrication d'hydroxylamines et produits ainsi obtenus
EP0080303A3 (fr) Couteau intérieur pour rasoir à sec du type feuille perforée
FR2296592A1 (fr) Procede de fabrication d'objets en carbone, et objets ainsi obtenus

Legal Events

Date Code Title Description
ST Notification of lapse