FR2383171B1 - - Google Patents

Info

Publication number
FR2383171B1
FR2383171B1 FR7807043A FR7807043A FR2383171B1 FR 2383171 B1 FR2383171 B1 FR 2383171B1 FR 7807043 A FR7807043 A FR 7807043A FR 7807043 A FR7807043 A FR 7807043A FR 2383171 B1 FR2383171 B1 FR 2383171B1
Authority
FR
France
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR7807043A
Other languages
French (fr)
Other versions
FR2383171A1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ER Squibb and Sons LLC
Original Assignee
ER Squibb and Sons LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ER Squibb and Sons LLC filed Critical ER Squibb and Sons LLC
Publication of FR2383171A1 publication Critical patent/FR2383171A1/en
Application granted granted Critical
Publication of FR2383171B1 publication Critical patent/FR2383171B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
FR7807043A 1977-03-11 1978-03-10 THIOPROPANOYLAMINOACID DERIVATIVES USEFUL AS HYPOTENSORS Granted FR2383171A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/776,792 US4108886A (en) 1977-03-11 1977-03-11 Thiopropanoylamino acid derivatives

Publications (2)

Publication Number Publication Date
FR2383171A1 FR2383171A1 (en) 1978-10-06
FR2383171B1 true FR2383171B1 (en) 1980-04-11

Family

ID=25108379

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7807043A Granted FR2383171A1 (en) 1977-03-11 1978-03-10 THIOPROPANOYLAMINOACID DERIVATIVES USEFUL AS HYPOTENSORS

Country Status (7)

Country Link
US (1) US4108886A (en)
JP (1) JPS53112810A (en)
BE (1) BE867269A (en)
CA (1) CA1090355A (en)
DE (1) DE2810261A1 (en)
FR (1) FR2383171A1 (en)
GB (1) GB1593712A (en)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT7851510A0 (en) * 1977-10-28 1978-10-16 Sandoz Ag AMIDES OF CYCLIC AMINO ACIDS THEIR PREPARATION AND THEIR APPLICATION AS MEDICINES
US4241076A (en) * 1978-02-21 1980-12-23 E. R. Squibb & Sons, Inc. Halogenated substituted mercaptoacylamino acids
IT1098328B (en) * 1978-06-16 1985-09-07 Gargani Pietro SODIUM SALT OF MERCAPROPROPIONYLGLYCIN, PROCESS FOR ITS PREPARATION AND THERAPEUTIC USES
CA1144930A (en) * 1978-08-11 1983-04-19 Miguel A. Ondetti Mercaptoacyl derivatives of substituted prolines
JPS5531022A (en) * 1978-08-24 1980-03-05 Yoshitomi Pharmaceut Ind Ltd Hydroxamic acid derivative and its preparation
US4690937A (en) * 1979-08-14 1987-09-01 University Of Miami Anti-hypertensive agents
US4690940A (en) * 1979-08-14 1987-09-01 University Of Miami Anti-hypertensive agents
US4690938A (en) * 1979-08-14 1987-09-01 University Of Miami Anti-hypertensive agents
US4695577A (en) * 1979-08-14 1987-09-22 University Of Miami Anti-hypertensive agents
US4690939A (en) * 1979-08-14 1987-09-01 University Of Miami Anti-hypertensive agents
ZA794723B (en) * 1978-09-11 1980-08-27 Univ Miami Anti-hypertensive agents
US4698355A (en) * 1979-08-14 1987-10-06 University Of Miami Anti-hypertensive agents
US4698356A (en) * 1979-08-14 1987-10-06 University Of Miami Anti-hypertensive agents
GR73585B (en) * 1978-09-11 1984-03-26 Univ Miami
JPS5829950B2 (en) * 1978-10-05 1983-06-25 ウェルファイド株式会社 Cyclic iminocarboxylic acid derivatives and their salts
US4198515A (en) * 1978-12-08 1980-04-15 E. R. Squibb & Sons, Inc. Mercaptoacyl derivatives of 4,5-dihydro-1H-pyrrole-2-carboxylic acids and 1,4,5,6-tetrahydropyridine-2-carboxylic acids
IT1111384B (en) * 1978-12-21 1986-01-13 Sigma Tau Ind Farmaceuti GUAIACYL ESTERS OF MERCAPTOPROPIONIC ACID DERIVATIVES PROCEDURE FOR THEIR PREPARATION AND THERAPEUTIC USE
EP0015544B1 (en) * 1979-03-06 1983-01-05 ZAMBON S.p.A. Derivatives of the mercaptopropionamido-acetic acid, process for the preparation thereof and compositions
JPS55164673A (en) * 1979-06-08 1980-12-22 Yoshitomi Pharmaceut Ind Ltd Zinc compound and its preparation
US4256761A (en) * 1979-07-13 1981-03-17 Usv Pharmaceutical Corporation Antihypertensive amides
US4291040A (en) * 1979-10-22 1981-09-22 E. R. Squibb & Sons, Inc. Mercaptoacyl derivatives of 4-disubstituted prolines and 4-substituted dehydroprolines
GB2065643B (en) * 1979-12-13 1983-08-24 Kanegafuchi Chemical Ind Optically active n-mercaptoalkanoylamino acids
US4734420A (en) * 1980-03-05 1988-03-29 University Of Miami Anti-hypertensive agents
US4690936A (en) * 1980-03-05 1987-09-01 University Of Miami Anti-hypertensive agents
AU542211B2 (en) * 1980-03-07 1985-02-14 Gruppo Lepetit S.P.A. Mercaptocycloalkyl carbonyl prolines
FR2480747A1 (en) * 1980-04-17 1981-10-23 Roques Bernard AMINO ACID DERIVATIVES AND THEIR THERAPEUTIC APPLICATION
ZA811340B (en) * 1980-06-09 1982-03-31 Morton Norwich Products Inc N-(cycloalkyl)amino acid compounds
US4316905A (en) * 1980-07-01 1982-02-23 E. R. Squibb & Sons, Inc. Mercaptoacyl derivatives of various 4-substituted prolines
US4512979A (en) * 1981-03-23 1985-04-23 Merck & Co., Inc. Dipeptides containing thialysine and related amino acids as antihypertensives
IE52884B1 (en) * 1981-05-11 1988-03-30 Sigma Tau Ind Farmaceuti 2-methoxyphenyl esters of n-substituted amino acids, their preparation and pharmaceutical use
IT1140394B (en) * 1981-12-23 1986-09-24 Maggioni Farma DIPEPTIDES CONTAINING A METHIONINE RESIDUE FOR HEPATOPROTECTIVE ACTIVITY
US4634716A (en) * 1982-09-30 1987-01-06 Merck & Co., Inc. Substituted N-carboxymethyl-aminoacylaminoalkanoic acids useful as antihypertensive agents
US5760241A (en) * 1995-12-28 1998-06-02 Zambon Group S.P.A. Thiol derivatives with metallopeptidase inhibitory activity
JP4525885B2 (en) * 2001-01-12 2010-08-18 三菱瓦斯化学株式会社 Photoresist developer and photoresist development method
CN103130692B (en) * 2011-12-02 2016-09-14 天津市国际生物医药联合研究院 The application in suppression NDM-1 activity of the 3-mercaptopropionyl aminated compounds

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3098078A (en) * 1958-02-19 1963-07-16 Ciba Geigy Corp Thio alkane carboxylic acids and functional derivatives thereof
FR1491204A (en) * 1962-08-10 1967-08-11 Santen Pharmaceutical Co Ltd Processes for the preparation of alpha- and beta mercaptopropionylglycocoll and their derivatives
CA946837A (en) * 1970-07-28 1974-05-07 Miguel A. Ondetti Enzyme inhibitor
CA1009252A (en) * 1972-10-03 1977-04-26 Santen Pharmaceutical Co. N-(mercaptoacyl) aminoacids
JPS6058230A (en) * 1983-09-09 1985-04-04 Babcock Hitachi Kk Waste gas desulfurization and apparatus thereof

Also Published As

Publication number Publication date
BE867269A (en) 1978-11-20
DE2810261C2 (en) 1988-04-28
JPS6216944B2 (en) 1987-04-15
FR2383171A1 (en) 1978-10-06
JPS53112810A (en) 1978-10-02
GB1593712A (en) 1981-07-22
CA1090355A (en) 1980-11-25
US4108886A (en) 1978-08-22
DE2810261A1 (en) 1978-09-14

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Legal Events

Date Code Title Description
ST Notification of lapse