FR2382432A1 - Slow-release anorectic diethylpropion resinate - prepared from sodium polystyrene sulphonate cation exchange resin and diethyl-amino-propiophenone hydrochloride - Google Patents
Slow-release anorectic diethylpropion resinate - prepared from sodium polystyrene sulphonate cation exchange resin and diethyl-amino-propiophenone hydrochlorideInfo
- Publication number
- FR2382432A1 FR2382432A1 FR7708599A FR7708599A FR2382432A1 FR 2382432 A1 FR2382432 A1 FR 2382432A1 FR 7708599 A FR7708599 A FR 7708599A FR 7708599 A FR7708599 A FR 7708599A FR 2382432 A1 FR2382432 A1 FR 2382432A1
- Authority
- FR
- France
- Prior art keywords
- resinate
- diethylpropion
- anorectic
- release
- exchange resin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F8/00—Chemical modification by after-treatment
- C08F8/44—Preparation of metal salts or ammonium salts
Abstract
Diethylpropion (2-diethylaminopropiophenone (I)) resinate comprises the combination of a sodium polystyrene sulphonate cation exchange resin and (I) hydrochloride. (I) is a known anorectic (BE 556756). This resinate gives prolonged release, an oral dose being released gradually over >=12 hrs. The resinate may be formulated in the classical forms for oral administration as pills, dragees, gelules, tablets, capsules, powders, suspensions, gels etc. And contains the equivalent of three normal doses taken over 12 hrs. One dose comprises 25-150 mg of the resinate, generally 75 mg. In vitro and in vivo tests are described. The product is stable, and has a longer half-eye than known slow release dipropion resinates.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
BE175015A BE851529A (en) | 1977-02-17 | 1977-02-17 | AMINE RESINATES, IN PARTICULAR DIETHYLPROPION, THEIR PREPARATION AND USE |
Publications (1)
Publication Number | Publication Date |
---|---|
FR2382432A1 true FR2382432A1 (en) | 1978-09-29 |
Family
ID=3842967
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7708599A Withdrawn FR2382432A1 (en) | 1977-02-17 | 1977-03-16 | Slow-release anorectic diethylpropion resinate - prepared from sodium polystyrene sulphonate cation exchange resin and diethyl-amino-propiophenone hydrochloride |
Country Status (3)
Country | Link |
---|---|
AT (1) | AT361634B (en) |
DE (1) | DE2806206C2 (en) |
FR (1) | FR2382432A1 (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1004310A1 (en) * | 1997-06-20 | 2000-05-31 | Ohkura Pharmaceutical Co., Ltd. | Gelled composition |
-
1977
- 1977-03-16 FR FR7708599A patent/FR2382432A1/en not_active Withdrawn
-
1978
- 1978-02-14 DE DE19782806206 patent/DE2806206C2/en not_active Expired
- 1978-02-16 AT AT110578A patent/AT361634B/en not_active IP Right Cessation
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1004310A1 (en) * | 1997-06-20 | 2000-05-31 | Ohkura Pharmaceutical Co., Ltd. | Gelled composition |
EP1004310A4 (en) * | 1997-06-20 | 2005-01-19 | Ohkura Pharmaceutical Co Ltd | Gelled composition |
Also Published As
Publication number | Publication date |
---|---|
DE2806206A1 (en) | 1978-08-24 |
AT361634B (en) | 1981-03-25 |
ATA110578A (en) | 1980-08-15 |
DE2806206C2 (en) | 1981-12-10 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ST | Notification of lapse |