FR2378783A2 - Thieno thienyl carbonyl phenyl alkanoic acid derivs. - having analgesic, antipyretic, antiinflammatory and platelet aggregation inhibiting activity - Google Patents

Thieno thienyl carbonyl phenyl alkanoic acid derivs. - having analgesic, antipyretic, antiinflammatory and platelet aggregation inhibiting activity

Info

Publication number
FR2378783A2
FR2378783A2 FR7702239A FR7702239A FR2378783A2 FR 2378783 A2 FR2378783 A2 FR 2378783A2 FR 7702239 A FR7702239 A FR 7702239A FR 7702239 A FR7702239 A FR 7702239A FR 2378783 A2 FR2378783 A2 FR 2378783A2
Authority
FR
France
Prior art keywords
thieno
thienyl
antipyretic
antiinflammatory
analgesic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7702239A
Other languages
French (fr)
Other versions
FR2378783B2 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rhone Poulenc Industries SA
Original Assignee
Rhone Poulenc Industries SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Industries SA filed Critical Rhone Poulenc Industries SA
Priority to FR7702239A priority Critical patent/FR2378783A2/en
Publication of FR2378783A2 publication Critical patent/FR2378783A2/en
Application granted granted Critical
Publication of FR2378783B2 publication Critical patent/FR2378783B2/fr
Granted legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Thieno 2,3-b thienyl carbonylphenylalkanoic acid derivs. of formula (I), their optical isomers, and acid addn. salts, are new. In (I), R is H, or alkyl; R1 is amino, alkylamino, dialkylamino or alkoxy, the various alkyl gps. being optn. substd. by a dialkylamino gp.; such that the alkyl gps. are 1-4C, the dialkylamino gp. may form a 5 or 6 membered heterocycle which may contain another O, N or S atom, and the thienothienyl carbonyl gp. is in the 3- or 4-posn. of the phenyl ring. A typical prod. is 2-diethylaminoethyl 2- (2-thieno 2,3-b thienyl)-3-carbonyl phenyl propionate. In an example this was prepd. by treating Na 2- (2-thieno 2,3-b thienyl)-3-carbonyl phenyl propionate with 2-diethylaminochloroethane in DMF at 25 degrees C.
FR7702239A 1977-01-27 1977-01-27 Thieno thienyl carbonyl phenyl alkanoic acid derivs. - having analgesic, antipyretic, antiinflammatory and platelet aggregation inhibiting activity Granted FR2378783A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR7702239A FR2378783A2 (en) 1977-01-27 1977-01-27 Thieno thienyl carbonyl phenyl alkanoic acid derivs. - having analgesic, antipyretic, antiinflammatory and platelet aggregation inhibiting activity

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7702239A FR2378783A2 (en) 1977-01-27 1977-01-27 Thieno thienyl carbonyl phenyl alkanoic acid derivs. - having analgesic, antipyretic, antiinflammatory and platelet aggregation inhibiting activity

Publications (2)

Publication Number Publication Date
FR2378783A2 true FR2378783A2 (en) 1978-08-25
FR2378783B2 FR2378783B2 (en) 1979-05-11

Family

ID=9185955

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7702239A Granted FR2378783A2 (en) 1977-01-27 1977-01-27 Thieno thienyl carbonyl phenyl alkanoic acid derivs. - having analgesic, antipyretic, antiinflammatory and platelet aggregation inhibiting activity

Country Status (1)

Country Link
FR (1) FR2378783A2 (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4798831A (en) * 1987-09-16 1989-01-17 Merck & Co., Inc. Substituted thieno[2,3-B]furan-2-sulfonamides as antiglaucoma agents
US4806562A (en) * 1987-08-03 1989-02-21 Merck & Co., Inc. Substituted thieno[2,3-b]thiophene-2-sulfonamides as antiglaucoma agents
US4894390A (en) * 1987-08-03 1990-01-16 Merck & Co., Inc. Substituted thieno[2,3-b]thiophene-2-sulfonamides as antiglaucoma agents

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
NEANT *

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4806562A (en) * 1987-08-03 1989-02-21 Merck & Co., Inc. Substituted thieno[2,3-b]thiophene-2-sulfonamides as antiglaucoma agents
US4894390A (en) * 1987-08-03 1990-01-16 Merck & Co., Inc. Substituted thieno[2,3-b]thiophene-2-sulfonamides as antiglaucoma agents
US4798831A (en) * 1987-09-16 1989-01-17 Merck & Co., Inc. Substituted thieno[2,3-B]furan-2-sulfonamides as antiglaucoma agents

Also Published As

Publication number Publication date
FR2378783B2 (en) 1979-05-11

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