JPS57109791A - Thiopyranopyridine derivative - Google Patents
Thiopyranopyridine derivativeInfo
- Publication number
- JPS57109791A JPS57109791A JP18840880A JP18840880A JPS57109791A JP S57109791 A JPS57109791 A JP S57109791A JP 18840880 A JP18840880 A JP 18840880A JP 18840880 A JP18840880 A JP 18840880A JP S57109791 A JPS57109791 A JP S57109791A
- Authority
- JP
- Japan
- Prior art keywords
- compound
- lower alkyl
- formulai
- phenyl
- thiopyranopyridine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- UHOVQNZJYSORNB-UHFFFAOYSA-N Benzene Chemical compound C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 abstract 3
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 3
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
- 208000007536 Thrombosis Diseases 0.000 abstract 1
- 238000004220 aggregation Methods 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 1
- 230000002744 anti-aggregatory effect Effects 0.000 abstract 1
- 229940121363 anti-inflammatory agent Drugs 0.000 abstract 1
- 239000002260 anti-inflammatory agent Substances 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 210000001772 blood platelet Anatomy 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 238000007363 ring formation reaction Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- LMBFAGIMSUYTBN-MPZNNTNKSA-N teixobactin Chemical compound C([C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H]1C(N[C@@H](C)C(=O)N[C@@H](C[C@@H]2NC(=N)NC2)C(=O)N[C@H](C(=O)O[C@H]1C)[C@@H](C)CC)=O)NC)C1=CC=CC=C1 LMBFAGIMSUYTBN-MPZNNTNKSA-N 0.000 abstract 1
Landscapes
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
NEW MATERIAL:A compound of formulaI(R<1> and R<2> are H, lower alkyl or phenyl which may have 1-2 groups selected from halogen, lower alkyl and lower alkoxyl; R<3> is H, lower alkyl, phenyl, etc.; X is O or S; Y is H, carboxyl or lower alkoxycarbonyl; n is 0 or 1; m is 0, 1 or 2) and a salt thereof. EXAMPLE:Methyl 2,3,4,5,6,7,7a,10,11,11a-decahydro-8H-oxazole [3,2-a]thiopyrano [4,3-b]pyridin-5-on -7a-yl-carboxylate. USE:Useful as an anti-inflammatory agent and a preventing agent and remedy for thrombosis, and having anti-inflammatory action and aggregation inhibitory action on blood platelets. PROCESS:A compound of formula II is subjected to the ring closing reaction with a compound of formula III in a suitable solvent, e.g. benzene, to give the compound of formulaI.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP18840880A JPS57109791A (en) | 1980-12-26 | 1980-12-26 | Thiopyranopyridine derivative |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP18840880A JPS57109791A (en) | 1980-12-26 | 1980-12-26 | Thiopyranopyridine derivative |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS57109791A true JPS57109791A (en) | 1982-07-08 |
JPS619954B2 JPS619954B2 (en) | 1986-03-27 |
Family
ID=16223123
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP18840880A Granted JPS57109791A (en) | 1980-12-26 | 1980-12-26 | Thiopyranopyridine derivative |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS57109791A (en) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS62196955A (en) * | 1986-02-25 | 1987-08-31 | Matsushita Electric Works Ltd | Extension interface circuit for single telephone ifu |
-
1980
- 1980-12-26 JP JP18840880A patent/JPS57109791A/en active Granted
Also Published As
Publication number | Publication date |
---|---|
JPS619954B2 (en) | 1986-03-27 |
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