FR2377998A1 - Nouveaux peptides et medicament contenant ces substances - Google Patents
Nouveaux peptides et medicament contenant ces substancesInfo
- Publication number
- FR2377998A1 FR2377998A1 FR7802000A FR7802000A FR2377998A1 FR 2377998 A1 FR2377998 A1 FR 2377998A1 FR 7802000 A FR7802000 A FR 7802000A FR 7802000 A FR7802000 A FR 7802000A FR 2377998 A1 FR2377998 A1 FR 2377998A1
- Authority
- FR
- France
- Prior art keywords
- amino acid
- group
- amino
- peptides
- alanine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 5
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 4
- 229940126601 medicinal product Drugs 0.000 title 1
- 239000000126 substance Substances 0.000 title 1
- 235000001014 amino acid Nutrition 0.000 abstract 8
- 229940024606 amino acid Drugs 0.000 abstract 8
- 150000001413 amino acids Chemical class 0.000 abstract 8
- 125000003277 amino group Chemical group 0.000 abstract 3
- DHMQDGOQFOQNFH-UHFFFAOYSA-N Glycine Chemical compound NCC(O)=O DHMQDGOQFOQNFH-UHFFFAOYSA-N 0.000 abstract 2
- NTYJJOPFIAHURM-UHFFFAOYSA-N Histamine Chemical compound NCCC1=CN=CN1 NTYJJOPFIAHURM-UHFFFAOYSA-N 0.000 abstract 2
- QNAYBMKLOCPYGJ-REOHCLBHSA-N L-alanine Chemical compound C[C@H](N)C(O)=O QNAYBMKLOCPYGJ-REOHCLBHSA-N 0.000 abstract 2
- 235000004279 alanine Nutrition 0.000 abstract 2
- 229960003767 alanine Drugs 0.000 abstract 2
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 2
- MTCFGRXMJLQNBG-REOHCLBHSA-N (2S)-2-Amino-3-hydroxypropansäure Chemical compound OC[C@H](N)C(O)=O MTCFGRXMJLQNBG-REOHCLBHSA-N 0.000 abstract 1
- DCXYFEDJOCDNAF-UHFFFAOYSA-N Asparagine Natural products OC(=O)C(N)CC(N)=O DCXYFEDJOCDNAF-UHFFFAOYSA-N 0.000 abstract 1
- 239000004471 Glycine Substances 0.000 abstract 1
- DCXYFEDJOCDNAF-REOHCLBHSA-N L-asparagine Chemical compound OC(=O)[C@@H](N)CC(N)=O DCXYFEDJOCDNAF-REOHCLBHSA-N 0.000 abstract 1
- ZDXPYRJPNDTMRX-VKHMYHEASA-N L-glutamine Chemical compound OC(=O)[C@@H](N)CCC(N)=O ZDXPYRJPNDTMRX-VKHMYHEASA-N 0.000 abstract 1
- COLNVLDHVKWLRT-QMMMGPOBSA-N L-phenylalanine Chemical compound OC(=O)[C@@H](N)CC1=CC=CC=C1 COLNVLDHVKWLRT-QMMMGPOBSA-N 0.000 abstract 1
- OUYCCCASQSFEME-QMMMGPOBSA-N L-tyrosine Chemical compound OC(=O)[C@@H](N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-QMMMGPOBSA-N 0.000 abstract 1
- MTCFGRXMJLQNBG-UHFFFAOYSA-N Serine Natural products OCC(N)C(O)=O MTCFGRXMJLQNBG-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 150000001370 alpha-amino acid derivatives Chemical class 0.000 abstract 1
- 235000008206 alpha-amino acids Nutrition 0.000 abstract 1
- 235000009582 asparagine Nutrition 0.000 abstract 1
- 229960001230 asparagine Drugs 0.000 abstract 1
- 125000003739 carbamimidoyl group Chemical group C(N)(=N)* 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 239000003292 glue Substances 0.000 abstract 1
- 235000004554 glutamine Nutrition 0.000 abstract 1
- 229960002743 glutamine Drugs 0.000 abstract 1
- ZDXPYRJPNDTMRX-UHFFFAOYSA-N glutamine Natural products OC(=O)C(N)CCC(N)=O ZDXPYRJPNDTMRX-UHFFFAOYSA-N 0.000 abstract 1
- 229960002449 glycine Drugs 0.000 abstract 1
- 229960001340 histamine Drugs 0.000 abstract 1
- 210000003630 histaminocyte Anatomy 0.000 abstract 1
- 230000002209 hydrophobic effect Effects 0.000 abstract 1
- 235000008729 phenylalanine Nutrition 0.000 abstract 1
- 229960005190 phenylalanine Drugs 0.000 abstract 1
- COLNVLDHVKWLRT-UHFFFAOYSA-N phenylalanine Natural products OC(=O)C(N)CC1=CC=CC=C1 COLNVLDHVKWLRT-UHFFFAOYSA-N 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 235000004400 serine Nutrition 0.000 abstract 1
- 229960001153 serine Drugs 0.000 abstract 1
- 210000002460 smooth muscle Anatomy 0.000 abstract 1
- 235000002374 tyrosine Nutrition 0.000 abstract 1
- 229960004441 tyrosine Drugs 0.000 abstract 1
- OUYCCCASQSFEME-UHFFFAOYSA-N tyrosine Natural products OC(=O)C(N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-UHFFFAOYSA-N 0.000 abstract 1
- 230000008728 vascular permeability Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1002—Tetrapeptides with the first amino acid being neutral
- C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
- C07K5/1008—Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atoms, i.e. Gly, Ala
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Biomedical Technology (AREA)
- Pulmonology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US76242777A | 1977-01-25 | 1977-01-25 | |
US87071378A | 1978-01-19 | 1978-01-19 |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2377998A1 true FR2377998A1 (fr) | 1978-08-18 |
FR2377998B1 FR2377998B1 (en, 2012) | 1980-08-29 |
Family
ID=27117118
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7802000A Granted FR2377998A1 (fr) | 1977-01-25 | 1978-01-25 | Nouveaux peptides et medicament contenant ces substances |
Country Status (5)
Country | Link |
---|---|
JP (1) | JPS53111014A (en, 2012) |
CH (1) | CH637628A5 (en, 2012) |
DE (1) | DE2803238A1 (en, 2012) |
FR (1) | FR2377998A1 (en, 2012) |
GB (1) | GB1568195A (en, 2012) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0312645B1 (de) * | 1987-10-23 | 1993-09-15 | PROGEN Biotechnik GmbH | Antigene Peptide des Komplementfaktors C3a, Verwendung der Peptide, Zell-Linien, Antikörper gegen die Peptide und Verwendung der Antikörper |
-
1978
- 1978-01-24 CH CH76178A patent/CH637628A5/de not_active IP Right Cessation
- 1978-01-24 GB GB2827/78A patent/GB1568195A/en not_active Expired
- 1978-01-25 FR FR7802000A patent/FR2377998A1/fr active Granted
- 1978-01-25 DE DE19782803238 patent/DE2803238A1/de not_active Withdrawn
- 1978-01-25 JP JP626178A patent/JPS53111014A/ja active Granted
Non-Patent Citations (2)
Title |
---|
CA1977 * |
NV6003/60 * |
Also Published As
Publication number | Publication date |
---|---|
CH637628A5 (en) | 1983-08-15 |
GB1568195A (en) | 1980-05-29 |
DE2803238A1 (de) | 1978-08-03 |
FR2377998B1 (en, 2012) | 1980-08-29 |
JPS53111014A (en) | 1978-09-28 |
JPH0133480B2 (en, 2012) | 1989-07-13 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
Johnson et al. | Regulation of lymphokine (gamma-interferon) production by corticotropin. | |
Takasaki et al. | Sarafotoxins S6: several isotoxins from Atractaspis engaddensis (burrowing asp) venom that affect the heart | |
Engineer et al. | The release of prostaglandins and thromboxanes from guinea-pig lung by slow reacting substance of anaphylaxis, and its inhibition | |
US5112810A (en) | Method for treating multiple sclerosis | |
FR2442054A1 (fr) | Proteines purifiees, notamment interferon, procede de preparation et compositions pharmaceutiques les contenant | |
DK524187D0 (da) | Aminosyrechelaterede midler til udlevering til specifikke biologiske vaevssteder | |
FR2385688A1 (fr) | Nouveaux peptides a activite biologique | |
ATE413189T1 (de) | Verfahren und zusammensetzungen zur behinderung der vervielfältigung von hiv-1 | |
EA199700294A1 (ru) | Фармацевтическая композиция, содержащая ингибиторы протонного насоса | |
CA2112907C (en) | Peptide which abrogates tnf and/or lps toxicity | |
KR840003414A (ko) | 3-히드록시부탄산 또는 이 산으로부터 유도된 염을 함유하는 약학적 조성물과, 의약품으로 사용할 수 있는 3-히드록시부탄산으로부터 유도된 화합물 | |
EP0298820A1 (fr) | Nouveaux dérivés peptidiques et leur application notamment en thérapeutique | |
NO915116L (no) | Ikke-glykosylerte human-interleukin-3-analogproteiner | |
FR2426462A1 (fr) | Preparation therapeutique destinee a l'administration parenterale de triglycerides contenant de la carnitine | |
EP0228192A3 (en) | Renin-inhibitory oligopeptides, their preparation and use | |
FR2377998A1 (fr) | Nouveaux peptides et medicament contenant ces substances | |
US6011014A (en) | Peptide T and related peptides in the treatment of inflammation, including multiple sclerosis | |
EP0960122A1 (en) | Myelopeptides and their therapeutic use | |
KR900701298A (ko) | T-세포 억제작용을 보유한 펩티드 | |
DE69715910T2 (de) | Pharmazeutische zusammensetzung enthaltend peptide für die inhibierung der immunoglobulin-rezeptor interaktion | |
Türker et al. | High degree of conversion of angiotensin I to angiotensin II in the mesenteric circulation of the isolated perfused terminal ileum of the cat | |
FR2694938B1 (fr) | Nouveaux peptides, anticorps diriges contre ces peptides, anticorps anti-idiotypiques, application a titre de medicaments, compositions pharmaceutiques et kits de diagnostic les renfermant. | |
EP0506653A1 (en) | Amino acid composition | |
DE3476666D1 (en) | Novel peptide, process for the preparation thereof and pharmaceutical composition containing said peptide | |
Kazuhiro et al. | Vasodilator effects of sarafotoxins and endothelin-1 in spontaneously hypertensive rats and rat isolated perfused mesentery |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
ST | Notification of lapse |