FR2375195A1 - Acides 1,2,2-trimethyl-3-carbamoylcyclopentane-1-carboxyliques substitues sur n et sels physiologiquement toleres de ceux-ci - Google Patents
Acides 1,2,2-trimethyl-3-carbamoylcyclopentane-1-carboxyliques substitues sur n et sels physiologiquement toleres de ceux-ciInfo
- Publication number
- FR2375195A1 FR2375195A1 FR7738981A FR7738981A FR2375195A1 FR 2375195 A1 FR2375195 A1 FR 2375195A1 FR 7738981 A FR7738981 A FR 7738981A FR 7738981 A FR7738981 A FR 7738981A FR 2375195 A1 FR2375195 A1 FR 2375195A1
- Authority
- FR
- France
- Prior art keywords
- mono
- alkylene
- choleretic
- gallstone
- dissolving
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- GSTRJEXEASEEIB-UHFFFAOYSA-N 3-carbamoyl-2,2,3-trimethylcyclopentane-1-carboxylic acid Chemical compound CC1(C)C(C(O)=O)CCC1(C)C(N)=O GSTRJEXEASEEIB-UHFFFAOYSA-N 0.000 title 1
- 102000004190 Enzymes Human genes 0.000 title 1
- 108090000790 Enzymes Proteins 0.000 title 1
- 239000000731 choleretic agent Substances 0.000 title 1
- 230000001989 choleretic effect Effects 0.000 title 1
- 208000001130 gallstones Diseases 0.000 title 1
- 230000028327 secretion Effects 0.000 title 1
- 230000004936 stimulating effect Effects 0.000 title 1
- YXFVVABEGXRONW-UHFFFAOYSA-N Toluene Chemical compound CC1=CC=CC=C1 YXFVVABEGXRONW-UHFFFAOYSA-N 0.000 abstract 3
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- JBDSSBMEKXHSJF-UHFFFAOYSA-N cyclopentanecarboxylic acid Chemical compound OC(=O)C1CCCC1 JBDSSBMEKXHSJF-UHFFFAOYSA-N 0.000 abstract 2
- LSPHULWDVZXLIL-LDWIPMOCSA-N (?)-Camphoric acid Chemical compound CC1(C)[C@@H](C(O)=O)CC[C@@]1(C)C(O)=O LSPHULWDVZXLIL-LDWIPMOCSA-N 0.000 abstract 1
- 229910052783 alkali metal Inorganic materials 0.000 abstract 1
- 150000001340 alkali metals Chemical group 0.000 abstract 1
- 125000004183 alkoxy alkyl group Chemical group 0.000 abstract 1
- 125000004171 alkoxy aryl group Chemical group 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 125000004181 carboxyalkyl group Chemical group 0.000 abstract 1
- 125000005026 carboxyaryl group Chemical group 0.000 abstract 1
- DDRPCXLAQZKBJP-UHFFFAOYSA-N furfurylamine Chemical compound NCC1=CC=CO1 DDRPCXLAQZKBJP-UHFFFAOYSA-N 0.000 abstract 1
- 125000004446 heteroarylalkyl group Chemical group 0.000 abstract 1
- 125000002768 hydroxyalkyl group Chemical group 0.000 abstract 1
- 125000005027 hydroxyaryl group Chemical group 0.000 abstract 1
- 150000007530 organic bases Chemical class 0.000 abstract 1
- 125000004076 pyridyl group Chemical group 0.000 abstract 1
- 238000010992 reflux Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
- C07D295/182—Radicals derived from carboxylic acids
- C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D307/52—Radicals substituted by nitrogen atoms not forming part of a nitro radical
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Gastroenterology & Hepatology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Furan Compounds (AREA)
- Pyridine Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19762659052 DE2659052A1 (de) | 1976-12-27 | 1976-12-27 | N-substituierte 1,2,2-trimethyl-3- carbamoyl-cyclopentan-carbonsaeuren(1) und deren physiologisch vertraegliche salze |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2375195A1 true FR2375195A1 (fr) | 1978-07-21 |
| FR2375195B1 FR2375195B1 (enExample) | 1981-07-24 |
Family
ID=5996769
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7738981A Granted FR2375195A1 (fr) | 1976-12-27 | 1977-12-23 | Acides 1,2,2-trimethyl-3-carbamoylcyclopentane-1-carboxyliques substitues sur n et sels physiologiquement toleres de ceux-ci |
Country Status (5)
| Country | Link |
|---|---|
| JP (1) | JPS5392737A (enExample) |
| AT (1) | AT351502B (enExample) |
| DE (1) | DE2659052A1 (enExample) |
| FR (1) | FR2375195A1 (enExample) |
| ZA (1) | ZA777604B (enExample) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2008017840A1 (en) * | 2006-08-08 | 2008-02-14 | Merlion Pharmaceuticals Sa | Cyclopentanecarboxylic acid derivatives and their use in the treatment of bacterial infectious diseases |
| KR101750420B1 (ko) * | 2009-01-09 | 2017-06-26 | 오키드 파마 리미티드 | 디펩티딜 펩티다제 ｉｖ 억제제 |
-
1976
- 1976-12-27 DE DE19762659052 patent/DE2659052A1/de not_active Withdrawn
-
1977
- 1977-12-22 ZA ZA00777604A patent/ZA777604B/xx unknown
- 1977-12-23 FR FR7738981A patent/FR2375195A1/fr active Granted
- 1977-12-27 AT AT933477A patent/AT351502B/de not_active IP Right Cessation
- 1977-12-27 JP JP15854477A patent/JPS5392737A/ja active Pending
Non-Patent Citations (4)
| Title |
|---|
| CA1931 * |
| CA1961 * |
| NV161/36 * |
| NV914/62 * |
Also Published As
| Publication number | Publication date |
|---|---|
| ZA777604B (en) | 1978-11-29 |
| FR2375195B1 (enExample) | 1981-07-24 |
| DE2659052A1 (de) | 1978-07-06 |
| JPS5392737A (en) | 1978-08-15 |
| AT351502B (de) | 1979-07-25 |
| ATA933477A (de) | 1979-01-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |