FR2372632A1 - NEW HEPARIN-BASED MEDICINAL PRODUCT ADMINISTRATIVE BY TRACHEO-BRONCHIAL AND ALVEOLAR ROUTE - Google Patents

NEW HEPARIN-BASED MEDICINAL PRODUCT ADMINISTRATIVE BY TRACHEO-BRONCHIAL AND ALVEOLAR ROUTE

Info

Publication number
FR2372632A1
FR2372632A1 FR7636431A FR7636431A FR2372632A1 FR 2372632 A1 FR2372632 A1 FR 2372632A1 FR 7636431 A FR7636431 A FR 7636431A FR 7636431 A FR7636431 A FR 7636431A FR 2372632 A1 FR2372632 A1 FR 2372632A1
Authority
FR
France
Prior art keywords
alveolar
tracheo
bronchial
medicinal product
heparin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7636431A
Other languages
French (fr)
Other versions
FR2372632B1 (en
Inventor
Claude Daniel Marcel Moreau
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Riker Laboratories Inc
Original Assignee
Riker Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Riker Laboratories Inc filed Critical Riker Laboratories Inc
Priority to FR7636431A priority Critical patent/FR2372632A1/en
Priority to BE184021A priority patent/BE862538A/en
Priority to LU78829A priority patent/LU78829A1/en
Priority to GB55078A priority patent/GB1560463A/en
Priority to NL7800230A priority patent/NL7800230A/en
Priority to DE19782801867 priority patent/DE2801867A1/en
Publication of FR2372632A1 publication Critical patent/FR2372632A1/en
Application granted granted Critical
Publication of FR2372632B1 publication Critical patent/FR2372632B1/fr
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/47—Hydrolases (3) acting on glycosyl compounds (3.2), e.g. cellulases, lactases

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Otolaryngology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

L'invention concerne un nouveau médicament à base d'héparine administrable par voie trachéo-bronchique et alvéolaire. Ce nouveau médicament est caractérisé par le fait qu'il est constitué d'une solution aqueuse d'héparine et d'au moins un agent chimique ou naturel connu pour accroître la perméabilité des muqueuses trachéo-bronchiques et alvéolaires. Application sous forme d'aerosol à des doses de 5 000 à 100 000 U.I. pour le traitement des accidents thromboemboliques, de l'atherosclérose, de l'infarctus du myocarde, des thromboses aigües artérielles, des embolies, des phlébites.The invention relates to a novel heparin-based medicament which can be administered via the tracheobronchial and alveolar routes. This new drug is characterized by the fact that it consists of an aqueous solution of heparin and at least one chemical or natural agent known to increase the permeability of the tracheobronchial and alveolar mucous membranes. Application in the form of aerosol at doses of 5,000 to 100,000 IU for the treatment of thromboembolic accidents, atherosclerosis, myocardial infarction, acute arterial thrombosis, embolism and phlebitis.

FR7636431A 1976-12-03 1976-12-03 NEW HEPARIN-BASED MEDICINAL PRODUCT ADMINISTRATIVE BY TRACHEO-BRONCHIAL AND ALVEOLAR ROUTE Granted FR2372632A1 (en)

Priority Applications (6)

Application Number Priority Date Filing Date Title
FR7636431A FR2372632A1 (en) 1976-12-03 1976-12-03 NEW HEPARIN-BASED MEDICINAL PRODUCT ADMINISTRATIVE BY TRACHEO-BRONCHIAL AND ALVEOLAR ROUTE
BE184021A BE862538A (en) 1976-12-03 1977-12-30 NEW HEPARIN-BASED MEDICINAL PRODUCT ADMINISTRATIVE BY TRACHEO-BRONCHIAL AND ALVEOLAR ROUTE
LU78829A LU78829A1 (en) 1976-12-03 1978-01-06 PROCESS FOR PREPARATION OF A NEW MEDICINAL BASED ON HEPARIN ADMINISTRABLE BY TRACHEO-BRONCHIAL AND ALVEOLAR ROUTE AND PRODUCT OBTAINED
GB55078A GB1560463A (en) 1976-12-03 1978-01-06 Heparin - based medicament adminstrable by the tracheo-bronchial and alveolar route
NL7800230A NL7800230A (en) 1976-12-03 1978-01-09 ANTI-COAGULANCE.
DE19782801867 DE2801867A1 (en) 1976-12-03 1978-01-17 ANTICOAGULAN MEDICINAL PRODUCTS BASED ON HEPARIN

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7636431A FR2372632A1 (en) 1976-12-03 1976-12-03 NEW HEPARIN-BASED MEDICINAL PRODUCT ADMINISTRATIVE BY TRACHEO-BRONCHIAL AND ALVEOLAR ROUTE

Publications (2)

Publication Number Publication Date
FR2372632A1 true FR2372632A1 (en) 1978-06-30
FR2372632B1 FR2372632B1 (en) 1979-03-23

Family

ID=9180598

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7636431A Granted FR2372632A1 (en) 1976-12-03 1976-12-03 NEW HEPARIN-BASED MEDICINAL PRODUCT ADMINISTRATIVE BY TRACHEO-BRONCHIAL AND ALVEOLAR ROUTE

Country Status (6)

Country Link
BE (1) BE862538A (en)
DE (1) DE2801867A1 (en)
FR (1) FR2372632A1 (en)
GB (1) GB1560463A (en)
LU (1) LU78829A1 (en)
NL (1) NL7800230A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6524557B1 (en) 1994-12-22 2003-02-25 Astrazeneca Ab Aerosol formulations of peptides and proteins

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4679555A (en) * 1984-08-07 1987-07-14 Key Pharmaceuticals, Inc. Method and apparatus for intrapulmonary delivery of heparin
DK1549337T3 (en) * 2002-02-18 2014-11-24 Ockham Biotech Ltd COMBINATION OF DNASE I AND GLYCOSAMINOGLYCANES FOR USE IN EXTRACELLULAR DNA CLEARANCE
DK1513502T3 (en) * 2002-02-18 2016-04-11 Ockham Biotech Ltd Combination therapy for airway disorders

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6524557B1 (en) 1994-12-22 2003-02-25 Astrazeneca Ab Aerosol formulations of peptides and proteins

Also Published As

Publication number Publication date
LU78829A1 (en) 1978-09-18
FR2372632B1 (en) 1979-03-23
GB1560463A (en) 1980-02-06
BE862538A (en) 1978-06-30
NL7800230A (en) 1979-07-11
DE2801867A1 (en) 1979-07-19

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Legal Events

Date Code Title Description
TP Transmission of property
ST Notification of lapse