FR2371422A1 - NEW PEPTIDES AND MEDICINAL PRODUCTS CONTAINING THESE SUBSTANCES - Google Patents

NEW PEPTIDES AND MEDICINAL PRODUCTS CONTAINING THESE SUBSTANCES

Info

Publication number
FR2371422A1
FR2371422A1 FR7735159A FR7735159A FR2371422A1 FR 2371422 A1 FR2371422 A1 FR 2371422A1 FR 7735159 A FR7735159 A FR 7735159A FR 7735159 A FR7735159 A FR 7735159A FR 2371422 A1 FR2371422 A1 FR 2371422A1
Authority
FR
France
Prior art keywords
substances
products containing
medicinal products
new peptides
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7735159A
Other languages
French (fr)
Other versions
FR2371422B1 (en
Inventor
Samuel Wilkinson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wellcome Foundation Ltd
Original Assignee
Wellcome Foundation Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Foundation Ltd filed Critical Wellcome Foundation Ltd
Publication of FR2371422A1 publication Critical patent/FR2371422A1/en
Application granted granted Critical
Publication of FR2371422B1 publication Critical patent/FR2371422B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/665—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
    • C07K14/675—Beta-endorphins
    • C07K14/6755—Beta-endorphins with at least 1 amino acid in D-form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/10—Laxatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/14—Antitussive agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1002—Tetrapeptides with the first amino acid being neutral
    • C07K5/1016—Tetrapeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Neurosurgery (AREA)
  • Pulmonology (AREA)
  • Biomedical Technology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

The novel peptides of the formula I R-(X<1>)m-(X<2>)n-X<3>-X<4>-X<5>-X<6>-R<1> (I> are prepared by allowing a compound of the formula II R-Y<1>-OH (II> to react with a compound of the formula III H-Y<2>-R<1> (III> The substituents in the formulae have the meanings given in Claim 1. The peptides of the formula I exhibit a morphine action.
FR7735159A 1976-11-23 1977-11-23 NEW PEPTIDES AND MEDICINAL PRODUCTS CONTAINING THESE SUBSTANCES Granted FR2371422A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB4882176 1976-11-23

Publications (2)

Publication Number Publication Date
FR2371422A1 true FR2371422A1 (en) 1978-06-16
FR2371422B1 FR2371422B1 (en) 1980-10-10

Family

ID=10450033

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7735159A Granted FR2371422A1 (en) 1976-11-23 1977-11-23 NEW PEPTIDES AND MEDICINAL PRODUCTS CONTAINING THESE SUBSTANCES

Country Status (4)

Country Link
JP (1) JPS5377037A (en)
CH (1) CH637626A5 (en)
DE (1) DE2752341A1 (en)
FR (1) FR2371422A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL79134A (en) * 1985-07-29 1991-06-10 American Cyanamid Co Continuous release peptide implants for parenteral administration

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2347336A1 (en) * 1976-04-08 1977-11-04 Ici Ltd Polypeptide enkephalin analogues - for use as analgesics by intravenous injection
FR2359120A1 (en) * 1976-07-19 1978-02-17 Sandoz Sa NEW POLYPEPTIDIC COMPOUNDS, THEIR PREPARATION AND THEIR APPLICATION AS MEDICINAL PRODUCTS

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2347336A1 (en) * 1976-04-08 1977-11-04 Ici Ltd Polypeptide enkephalin analogues - for use as analgesics by intravenous injection
FR2359120A1 (en) * 1976-07-19 1978-02-17 Sandoz Sa NEW POLYPEPTIDIC COMPOUNDS, THEIR PREPARATION AND THEIR APPLICATION AS MEDICINAL PRODUCTS

Also Published As

Publication number Publication date
FR2371422B1 (en) 1980-10-10
CH637626A5 (en) 1983-08-15
DE2752341A1 (en) 1978-05-24
JPS5377037A (en) 1978-07-08

Similar Documents

Publication Publication Date Title
FR2338925A1 (en) NEW PEPTIDES AND MEDICINAL PRODUCTS CONTAINING THESE SUBSTANCES
MY102236A (en) New aryl derivatives
FI65775B (en) REFERENCE FOR A LOADER THERAPEUTIC FRAME
ZA747760B (en) Improvements in and relating to compounds having a physiological cooling effect and compositions containing them
FR2274673A1 (en) AROMATIC ALKYL PRODUCTION
BE841870A (en) STABLE INSULIN PREPARATION
ZA747985B (en) Smoke suppressants for halogencontaining plastics compositions
BE820717A (en) THERMOSETTING SEALING COMPOSITIONS
FR2392971A1 (en) PROSTANOIC ACID DERIVATIVES, THEIR PREPARATION AND MEDICINAL PRODUCT CONTAINING SUCH SUBSTANCES
IT1093261B (en) TCOPOLIETERES TERAMIDS STABLE TO HYDROLYSIS
DK452379A (en) CLOSE TO A FORMULA BAG CONTAINING INFUSION CASE
IT1079395B (en) ALCHYLAMIDS N-ALCHINYL ((PHENOXY-SUBSTITUTED) COMPOSITIONS CONTAINING THEM AND PROCEDURE TO PRODUCE THEM
SE430373B (en) BACTERICID COMPOSITION CONTAINING A BACTERICIDIC QUARTERED AMMONIUM SALT AND A 3-ISOPHIAZOLONE
FR2374039A1 (en) COMPOSITIONS CONTAINING A DERIVATIVE OF SALICYLIC ACID AND MEDICINAL APPLICATIONS
IT1188985B (en) HETEROCYCLIC PHENOSMIA REPLACED PROCEDURE TO PREPARE THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
IT7949064A0 (en) IMPROVEMENT IN PHARMACEUTICAL COMPOSITIONS CONTAINING PROSTAGLANDIN
FR2371422A1 (en) NEW PEPTIDES AND MEDICINAL PRODUCTS CONTAINING THESE SUBSTANCES
BE875142A (en) STABILIZED ANAEROBIC COMPOSITIONS CONTAINING ACIDS
NL7410335A (en) IMPROVEMENTS IN OR RELATING TO INJECTION MOLDING EQUIPMENT.
BE846542A (en) NEW BASIC SUBSTITUTE PYRIDINECARBOXAMIDES USEFUL AS MEDICINAL PRODUCTS
BE836559A (en) DISINFECTANT COMPOSITIONS OF OXYDIACETALDEHYDE
FR2427328A1 (en) DIPHENYL ETHERS AND MEDICINAL PRODUCTS CONTAINING THESE SUBSTANCES
FR2361361A1 (en) NEW DERIVATIVES OF CYCLOPENTANE AND MEDICINAL PRODUCTS CONTAINING THESE SUBSTANCES
IT1056132B (en) SUBSTITUTED AMINO ACID DERIVATIVES PROCEDURE TO PRODUCE THEM AND FUNGICIDAL COMPOSITIONS CONTAINING THEM
IL47503A0 (en) Novel heterocyclic compounds,their preparation and pharmaceutical compositions containing them

Legal Events

Date Code Title Description
ST Notification of lapse