FR2370053A1 - Acides 7-acylamino-3-(1-(2,3-dihydroxypropyl)tetrazole-5-ylthiomethyl)-3-cepheme-4-carboxyliques et leur application en therapeutique - Google Patents

Acides 7-acylamino-3-(1-(2,3-dihydroxypropyl)tetrazole-5-ylthiomethyl)-3-cepheme-4-carboxyliques et leur application en therapeutique

Info

Publication number
FR2370053A1
FR2370053A1 FR7732404A FR7732404A FR2370053A1 FR 2370053 A1 FR2370053 A1 FR 2370053A1 FR 7732404 A FR7732404 A FR 7732404A FR 7732404 A FR7732404 A FR 7732404A FR 2370053 A1 FR2370053 A1 FR 2370053A1
Authority
FR
France
Prior art keywords
dihydroxypropyl
tetrazole
acylamino
carboxylic acids
cepheme
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7732404A
Other languages
English (en)
Other versions
FR2370053B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GlaxoSmithKline LLC
Original Assignee
SmithKline Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Corp filed Critical SmithKline Corp
Publication of FR2370053A1 publication Critical patent/FR2370053A1/fr
Application granted granted Critical
Publication of FR2370053B1 publication Critical patent/FR2370053B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/36—Methylene radicals, substituted by sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

L'invention a pour objet des acides 7-acylamino-3-Ø1-(2,3-dihydroxypropyl) tétrazole - 5 - ylthiométhylõ-3-céphème-4-carboxyliques et leur application en thérapeutique comme agents antibactériens.
FR7732404A 1976-11-04 1977-10-27 Acides 7-acylamino-3-(1-(2,3-dihydroxypropyl)tetrazole-5-ylthiomethyl)-3-cepheme-4-carboxyliques et leur application en therapeutique Granted FR2370053A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/738,774 US4064242A (en) 1976-11-04 1976-11-04 7-Acylamino-3-[1-(2,3-dihydroxypropyl)tetrazole-5-ylthiomethyl]-3-cephem-4-carboxylic acids

Publications (2)

Publication Number Publication Date
FR2370053A1 true FR2370053A1 (fr) 1978-06-02
FR2370053B1 FR2370053B1 (fr) 1980-12-19

Family

ID=24969418

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7732404A Granted FR2370053A1 (fr) 1976-11-04 1977-10-27 Acides 7-acylamino-3-(1-(2,3-dihydroxypropyl)tetrazole-5-ylthiomethyl)-3-cepheme-4-carboxyliques et leur application en therapeutique

Country Status (5)

Country Link
US (1) US4064242A (fr)
JP (1) JPS5359691A (fr)
DE (1) DE2749272A1 (fr)
FR (1) FR2370053A1 (fr)
GB (1) GB1592883A (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4226806A (en) * 1977-11-07 1980-10-07 Yeda Research And Development Co. Ltd. 7-[(Sulfomethyl)phenyl]acetamidocephalosporin derivatives
NL8100089A (nl) 1980-01-17 1981-08-17 Rhone Poulenc Ind Nieuwe thiolen en de bereiding daarvan.
US8434905B2 (en) * 2008-11-15 2013-05-07 Rongsheng Tian LED based precision approach path indicator

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2223002A1 (fr) * 1973-03-30 1974-10-25 Fujisawa Pharmaceutical Co
FR2322603A1 (fr) * 1975-09-02 1977-04-01 Smithkline Corp Nouvelles cephalosporines, leur procede de preparation et leurs applications pharmaceutiques

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3993758A (en) * 1974-01-18 1976-11-23 Beecham Group Limited Cephalosporin compounds

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2223002A1 (fr) * 1973-03-30 1974-10-25 Fujisawa Pharmaceutical Co
FR2322603A1 (fr) * 1975-09-02 1977-04-01 Smithkline Corp Nouvelles cephalosporines, leur procede de preparation et leurs applications pharmaceutiques

Also Published As

Publication number Publication date
JPS5359691A (en) 1978-05-29
GB1592883A (en) 1981-07-08
DE2749272A1 (de) 1978-05-11
US4064242A (en) 1977-12-20
FR2370053B1 (fr) 1980-12-19

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Legal Events

Date Code Title Description
ST Notification of lapse