FR2366835A1 - SHAPED ELEMENT INTENDED TO CONTAIN A CHEMICAL SUBSTANCE, ITS PREPARATION PROCESS AND PACKAGING THE CONTAINER - Google Patents

SHAPED ELEMENT INTENDED TO CONTAIN A CHEMICAL SUBSTANCE, ITS PREPARATION PROCESS AND PACKAGING THE CONTAINER

Info

Publication number
FR2366835A1
FR2366835A1 FR7729663A FR7729663A FR2366835A1 FR 2366835 A1 FR2366835 A1 FR 2366835A1 FR 7729663 A FR7729663 A FR 7729663A FR 7729663 A FR7729663 A FR 7729663A FR 2366835 A1 FR2366835 A1 FR 2366835A1
Authority
FR
France
Prior art keywords
water
carrier
packaging
container
contain
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7729663A
Other languages
French (fr)
Other versions
FR2366835B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
John Wyeth and Brother Ltd
Original Assignee
John Wyeth and Brother Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB41483/76A external-priority patent/GB1548022A/en
Application filed by John Wyeth and Brother Ltd filed Critical John Wyeth and Brother Ltd
Publication of FR2366835A1 publication Critical patent/FR2366835A1/en
Application granted granted Critical
Publication of FR2366835B1 publication Critical patent/FR2366835B1/fr
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2063—Proteins, e.g. gelatin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Zoology (AREA)
  • Medicinal Preparation (AREA)
  • Container Filling Or Packaging Operations (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

The carrier disintegrates within at most ten seconds in water and has a chemical- and/or pharmaceutical-containing matrix having an open network. This consists of a water-soluble or water-dispersible and/or pharmaceutically tolerable excipient which is inert to the chemicals or pharmaceuticals. The carrier can be prepared by subjecting a solution of the excipient which contains the chemicals or pharmaceuticals to freeze-drying in a mould. This method can be carried out advantageously in a mould which consists of a film having appropriate depressions. After formation of the pill-like carrier, a covering film is stuck on and a finished pack is obtained at the same time. The product according to the invention has the advantage of an administration of medicaments which is more pleasant for the user.
FR7729663A 1976-10-06 1977-10-03 SHAPED ELEMENT INTENDED TO CONTAIN A CHEMICAL SUBSTANCE, ITS PREPARATION PROCESS AND PACKAGING THE CONTAINER Granted FR2366835A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB41483/76A GB1548022A (en) 1976-10-06 1976-10-06 Pharmaceutial dosage forms
GB3039977 1977-07-20

Publications (2)

Publication Number Publication Date
FR2366835A1 true FR2366835A1 (en) 1978-05-05
FR2366835B1 FR2366835B1 (en) 1980-10-24

Family

ID=26260429

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7729663A Granted FR2366835A1 (en) 1976-10-06 1977-10-03 SHAPED ELEMENT INTENDED TO CONTAIN A CHEMICAL SUBSTANCE, ITS PREPARATION PROCESS AND PACKAGING THE CONTAINER

Country Status (12)

Country Link
JP (1) JPS5344619A (en)
AU (1) AU513845B2 (en)
CH (1) CH633717A5 (en)
CY (1) CY1129A (en)
DE (1) DE2744493A1 (en)
FR (1) FR2366835A1 (en)
HK (1) HK58081A (en)
IE (1) IE45770B1 (en)
KE (1) KE3171A (en)
LU (1) LU78259A1 (en)
MY (1) MY8200187A (en)
NL (1) NL189898C (en)

Cited By (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2455459A1 (en) * 1979-05-02 1980-11-28 Sertog Carboxy:methylcellulose matrix for slow release of volatile cpd. - contains tri:ethanolamine, stearin and an alcohol e.g. cetyl is esp. useful for perfumes, insect repellents eczema treatment etc.
EP0265226A2 (en) * 1986-10-21 1988-04-27 American Home Products Corporation Spray dried acetaminophen
EP0266113A1 (en) * 1986-10-21 1988-05-04 American Home Products Corporation Spray dried acetaminophen
EP0267702A2 (en) * 1986-10-21 1988-05-18 American Home Products Corporation Spray dried acetaminophen
EP0268383A1 (en) * 1986-10-21 1988-05-25 American Home Products Corporation Spray dried acetaminophen
EP0352190A1 (en) 1988-07-21 1990-01-24 Farmalyoc Solid and unitary form containing microparticules and/or nanoparticules, and its preparation
EP0438358A1 (en) 1990-01-19 1991-07-24 Farmalyoc Solid porous unit dosage form containing particles in bead form as well as its preparation
EP0450141A1 (en) * 1989-08-14 1991-10-09 Janssen Pharmaceutica Inc. Carrier material for administration of drugs
WO1993012770A1 (en) * 1991-12-20 1993-07-08 Pfizer Inc. Porous shaped delivery devices and method of producing thereof
WO1994001090A1 (en) * 1992-07-03 1994-01-20 Alfatec-Pharma Gmbh Solid and liquid solutions of drugs which are not readily soluble in water
WO1995023600A1 (en) * 1994-03-02 1995-09-08 Akzo Nobel N.V. Sublingual or buccal pharmaceutical composition
WO1996013251A1 (en) * 1994-10-28 1996-05-09 R.P. Scherer Corporation Process for preparing solid pharmaceutical dosage forms of hydrophobic substances
WO1996026714A1 (en) * 1995-03-02 1996-09-06 R.P. Scherer Limited Process for the preparation of a solid pharmaceutical dosage form
WO1997006786A1 (en) * 1995-08-18 1997-02-27 R.P. Scherer Limited Oral fast-dissolving compositions for dopamine agonists
WO1999009989A1 (en) * 1997-08-21 1999-03-04 R. P. Scherer Limited Pharmaceutical composition containing midazolam
WO1999017754A1 (en) * 1997-10-08 1999-04-15 Sepracor Inc. Dosage form for aerosol administration

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE53696B1 (en) * 1981-12-02 1989-01-18 Wyeth John & Brother Ltd Solid shaped articles
AT385200B (en) * 1986-07-22 1988-02-25 Kwizda Fa F Johann Process for the production of tablets with delayed release characteristics of medicinal substances
JPH02247447A (en) * 1989-03-17 1990-10-03 Matsushita Refrig Co Ltd Control method for air conditioner
FR2647343B1 (en) * 1989-05-24 1994-05-06 Rhone Poulenc Sante NOVEL POROUS PHARMACEUTICAL FORM AND ITS PREPARATION
JPH0331644A (en) * 1989-06-28 1991-02-12 Matsushita Refrig Co Ltd Controller for air conditioner
ATE172637T1 (en) 1991-12-24 1998-11-15 Yamanouchi Pharma Co Ltd INTRABUCCAL DISINTEGRATION PREPARATION AND PRODUCTION THEREOF
DE4342091A1 (en) * 1993-12-09 1995-06-14 Asta Medica Ag Products for the application of initially high doses of Cetrorelix and manufacture of a combination pack for use in the treatment of diseases
US5738875A (en) * 1994-10-28 1998-04-14 R.P. Scherer Corporation Process for preparing solid pharmaceutical dosage forms
US8071128B2 (en) 1996-06-14 2011-12-06 Kyowa Hakko Kirin Co., Ltd. Intrabuccally rapidly disintegrating tablet and a production method of the tablets
DK0914818T3 (en) 1996-06-14 2005-07-04 Kyowa Hakko Kogyo Kk Intraoral fast disintegrable tablet
TW527195B (en) 1997-10-09 2003-04-11 Ssp Co Ltd Fast-soluble solid pharmaceutical combinations
GB9722682D0 (en) * 1997-10-27 1997-12-24 Scherer Ltd R P Pharmaceutical products
GB9901819D0 (en) * 1999-01-27 1999-03-17 Scherer Corp R P Pharmaceutical compositions
GB9908014D0 (en) * 1999-04-08 1999-06-02 Scherer Corp R P Pharmaceutical compositions
US9358214B2 (en) 2001-10-04 2016-06-07 Adare Pharmaceuticals, Inc. Timed, sustained release systems for propranolol
JP4173670B2 (en) * 2002-03-08 2008-10-29 旭化成ファーマ株式会社 Orally disintegrating preparation
GB0226076D0 (en) * 2002-11-08 2002-12-18 Rp Scherer Technologies Inc Improved formulations containing substituted imidazole derivatives
MXPA05009079A (en) * 2003-02-28 2006-05-19 Alk Abello As Dosage form having a saccharide matrix.
US9884014B2 (en) 2004-10-12 2018-02-06 Adare Pharmaceuticals, Inc. Taste-masked pharmaceutical compositions
CA2584957C (en) 2004-10-21 2015-08-25 Eurand Pharmaceuticals Limited Taste-masked pharmaceutical compositions with gastrosoluble pore-formers
US9161918B2 (en) 2005-05-02 2015-10-20 Adare Pharmaceuticals, Inc. Timed, pulsatile release systems
US20080031944A1 (en) * 2006-08-04 2008-02-07 Cima Labs Inc. Stabilization of lorazepam
SG10201407965XA (en) 2009-12-02 2015-02-27 Aptalis Pharma Ltd Fexofenadine microcapsules and compositions containing them
JP2012121850A (en) * 2010-12-09 2012-06-28 Otsuka Pharmaceut Co Ltd Oral fast-dissolving composition of aripiprazole
JP2015172084A (en) * 2015-07-06 2015-10-01 大塚製薬株式会社 Quickly-soluble oral composition of aripiprazole
JP6572257B2 (en) * 2017-05-16 2019-09-04 大塚製薬株式会社 Aripiprazole oral fast-dissolving composition

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2017373A1 (en) * 1969-04-15 1971-04-22 Orsymonde S A , Paris Lyophilized products and processes for their manufacture
FR2179044A1 (en) * 1972-04-03 1973-11-16 Scherer Corp R P
FR2199973A1 (en) * 1972-09-20 1974-04-19 Boehringer Mannheim Gmbh
FR2335205A2 (en) * 1975-12-16 1977-07-15 Boehringer Mannheim Gmbh PROCESS FOR THE MANUFACTURE OF POROUS TABLETS

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2166074A (en) * 1937-04-09 1939-07-11 Sharp & Dohme Inc Gelatinous colloids
GB836811A (en) * 1955-07-08 1960-06-09 Ciba Ltd Shaped medicament carriers and process for their manufacture
GB1083896A (en) * 1964-04-30 1967-09-20 Dunster Lab Ltd Vehicles for administering drugs

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2017373A1 (en) * 1969-04-15 1971-04-22 Orsymonde S A , Paris Lyophilized products and processes for their manufacture
FR2179044A1 (en) * 1972-04-03 1973-11-16 Scherer Corp R P
FR2199973A1 (en) * 1972-09-20 1974-04-19 Boehringer Mannheim Gmbh
FR2335205A2 (en) * 1975-12-16 1977-07-15 Boehringer Mannheim Gmbh PROCESS FOR THE MANUFACTURE OF POROUS TABLETS

Cited By (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2455459A1 (en) * 1979-05-02 1980-11-28 Sertog Carboxy:methylcellulose matrix for slow release of volatile cpd. - contains tri:ethanolamine, stearin and an alcohol e.g. cetyl is esp. useful for perfumes, insect repellents eczema treatment etc.
EP0265226A2 (en) * 1986-10-21 1988-04-27 American Home Products Corporation Spray dried acetaminophen
EP0266113A1 (en) * 1986-10-21 1988-05-04 American Home Products Corporation Spray dried acetaminophen
EP0267702A2 (en) * 1986-10-21 1988-05-18 American Home Products Corporation Spray dried acetaminophen
EP0268383A1 (en) * 1986-10-21 1988-05-25 American Home Products Corporation Spray dried acetaminophen
EP0267702A3 (en) * 1986-10-21 1989-06-14 American Home Products Corporation Spray dried acetaminophen
EP0265226A3 (en) * 1986-10-21 1989-07-19 American Home Products Corporation Spray dried acetaminophen
EP0352190A1 (en) 1988-07-21 1990-01-24 Farmalyoc Solid and unitary form containing microparticules and/or nanoparticules, and its preparation
US5079018A (en) * 1989-08-14 1992-01-07 Neophore Technologies, Inc. Freeze dry composition and method for oral administration of drugs, biologicals, nutrients and foodstuffs
EP0450141A1 (en) * 1989-08-14 1991-10-09 Janssen Pharmaceutica Inc. Carrier material for administration of drugs
EP0438358A1 (en) 1990-01-19 1991-07-24 Farmalyoc Solid porous unit dosage form containing particles in bead form as well as its preparation
WO1993012770A1 (en) * 1991-12-20 1993-07-08 Pfizer Inc. Porous shaped delivery devices and method of producing thereof
WO1994001090A1 (en) * 1992-07-03 1994-01-20 Alfatec-Pharma Gmbh Solid and liquid solutions of drugs which are not readily soluble in water
US5763476A (en) * 1994-03-02 1998-06-09 Akzo Noble N.V. Sublingual or buccal pharmaceutical composition
WO1995023600A1 (en) * 1994-03-02 1995-09-08 Akzo Nobel N.V. Sublingual or buccal pharmaceutical composition
US5827541A (en) * 1994-10-28 1998-10-27 R. P. Scherer Corporation Process for preparing solid pharmaceutical dosage forms of hydrophobic substances
WO1996013251A1 (en) * 1994-10-28 1996-05-09 R.P. Scherer Corporation Process for preparing solid pharmaceutical dosage forms of hydrophobic substances
WO1996026714A1 (en) * 1995-03-02 1996-09-06 R.P. Scherer Limited Process for the preparation of a solid pharmaceutical dosage form
US6423342B1 (en) 1995-03-02 2002-07-23 R. P. Scherer Corporation Process for the preparation of a solid pharmaceutical dosage form
WO1997006786A1 (en) * 1995-08-18 1997-02-27 R.P. Scherer Limited Oral fast-dissolving compositions for dopamine agonists
US6316027B1 (en) 1995-08-18 2001-11-13 R. P. Scherer Technologies, Inc. Fast-dissolving dosage forms for dopamine agonists
WO1999009989A1 (en) * 1997-08-21 1999-03-04 R. P. Scherer Limited Pharmaceutical composition containing midazolam
WO1999017754A1 (en) * 1997-10-08 1999-04-15 Sepracor Inc. Dosage form for aerosol administration

Also Published As

Publication number Publication date
DE2744493A1 (en) 1978-04-13
FR2366835B1 (en) 1980-10-24
HK58081A (en) 1981-12-04
IE45770L (en) 1978-04-06
CY1129A (en) 1982-02-19
JPS6250445B2 (en) 1987-10-24
NL7710876A (en) 1978-04-10
AU513845B2 (en) 1981-01-08
IE45770B1 (en) 1982-11-17
DE2744493C2 (en) 1991-07-18
AU2882577A (en) 1979-03-22
NL189898B (en) 1993-04-01
LU78259A1 (en) 1978-06-09
JPS5344619A (en) 1978-04-21
MY8200187A (en) 1982-12-31
NL189898C (en) 1993-09-01
KE3171A (en) 1981-12-18
CH633717A5 (en) 1982-12-31

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