FR2366016A2 - Nouveaux indoles substitues, leur procede de preparation et leur application comme medicament - Google Patents
Nouveaux indoles substitues, leur procede de preparation et leur application comme medicamentInfo
- Publication number
- FR2366016A2 FR2366016A2 FR7629652A FR7629652A FR2366016A2 FR 2366016 A2 FR2366016 A2 FR 2366016A2 FR 7629652 A FR7629652 A FR 7629652A FR 7629652 A FR7629652 A FR 7629652A FR 2366016 A2 FR2366016 A2 FR 2366016A2
- Authority
- FR
- France
- Prior art keywords
- prepd
- methyl ester
- analgesic
- dimethylamino
- reacting
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 150000004702 methyl esters Chemical class 0.000 title abstract 2
- 125000004103 aminoalkyl group Chemical group 0.000 title 1
- 230000000202 analgesic effect Effects 0.000 title 1
- 229960002887 deanol Drugs 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- SIKJAQJRHWYJAI-UHFFFAOYSA-N Indole Chemical compound C1=CC=C2NC=CC2=C1 SIKJAQJRHWYJAI-UHFFFAOYSA-N 0.000 abstract 2
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- 125000002947 alkylene group Chemical group 0.000 abstract 2
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 150000002367 halogens Chemical class 0.000 abstract 2
- KBSGZKXXWYLYTK-UHFFFAOYSA-N 2-(dimethylamino)ethyl 2-[6-methoxy-3-(4-methoxybenzoyl)-2-methylindol-1-yl]acetate Chemical compound C1=CC(OC)=CC=C1C(=O)C1=C(C)N(CC(=O)OCCN(C)C)C2=CC(OC)=CC=C12 KBSGZKXXWYLYTK-UHFFFAOYSA-N 0.000 abstract 1
- UEEJHVSXFDXPFK-UHFFFAOYSA-N N-dimethylaminoethanol Chemical compound CN(C)CCO UEEJHVSXFDXPFK-UHFFFAOYSA-N 0.000 abstract 1
- 125000004414 alkyl thio group Chemical group 0.000 abstract 1
- PZOUSPYUWWUPPK-UHFFFAOYSA-N indole Natural products CC1=CC=CC2=C1C=CN2 PZOUSPYUWWUPPK-UHFFFAOYSA-N 0.000 abstract 1
- RKJUIXBNRJVNHR-UHFFFAOYSA-N indolenine Natural products C1=CC=C2CC=NC2=C1 RKJUIXBNRJVNHR-UHFFFAOYSA-N 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- -1 piperidino, pyrrolidino, morpholino, 1-piperazinyl Chemical group 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/12—Radicals substituted by oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Indole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (22)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7629652A FR2366016A2 (fr) | 1976-10-01 | 1976-10-01 | Nouveaux indoles substitues, leur procede de preparation et leur application comme medicament |
| SE7613991A SE421917B (sv) | 1976-01-21 | 1976-12-13 | Analogiforfarande for framstellning av nya derivat av 2-metyl-1-indolyl-ettikssyra med terapeutisk verkan |
| ES454732A ES454732A1 (es) | 1976-01-21 | 1976-12-31 | Procedimiento de preparacion de nuevos modelos sustituidos. |
| AR266109A AR216755A1 (es) | 1976-01-21 | 1977-01-05 | Procedimiento de preparacion de nuevos derivados de 2-metil-3-(4-benzoilo sustituido)-(1h)-indol-1-acetato de alquilenamina |
| IL51217A IL51217A (en) | 1976-01-21 | 1977-01-06 | 3-benzoyl-2-methyl-1-dialkyl(or cyclic)amino alkyl 1-(1h)indole acetate derivatives |
| HU77RO908A HU175413B (hu) | 1976-01-21 | 1977-01-07 | Sposob poluchenija zamehhennykh proizvodnykh indola i farmacevticheskikh kompozicijj soderzhahhikh ikh aktivnymi agentami |
| US05/758,633 US4105777A (en) | 1976-01-21 | 1977-01-12 | Indoles |
| DE19772701095 DE2701095A1 (de) | 1976-01-21 | 1977-01-12 | Neue substituierte indole, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammensetzungen |
| AT26077A AT357517B (de) | 1976-01-21 | 1977-01-18 | Verfahren zur herstellung neuer substituierter indole und von deren saeureadditionssalzen |
| IE117/77A IE44337B1 (en) | 1976-01-21 | 1977-01-20 | Substituted indole-1-acetates |
| AU21489/77A AU512091B1 (en) | 1976-01-21 | 1977-01-20 | Substituted indoles |
| GR52611A GR61775B (en) | 1976-01-21 | 1977-01-20 | Preparation process of indole substitutes |
| PT66094A PT66094B (fr) | 1976-01-21 | 1977-01-20 | Procede de preparation de nouveaux indoles substitues |
| CA270,138A CA1091233A (fr) | 1976-01-21 | 1977-01-20 | Procede de preparation de nouveaux indoles substitues |
| LU76612A LU76612A1 (enrdf_load_stackoverflow) | 1976-01-21 | 1977-01-20 | |
| DK20977A DK20977A (da) | 1976-01-21 | 1977-01-20 | Fremgangsmade til fremstilling af substituerede indoler eller syreadditionssalte deraf |
| GB2379/77A GB1523703A (en) | 1976-01-21 | 1977-01-20 | Substituted indole - 1 - acetates |
| AU21489/77D AU2148977A (en) | 1976-01-21 | 1977-01-20 | Substituted indoles |
| CH78677A CH599154A5 (enrdf_load_stackoverflow) | 1976-01-21 | 1977-01-21 | |
| JP504777A JPS5291858A (en) | 1976-01-21 | 1977-01-21 | Production of novel substituted indole and pharmaceutical composition |
| NL7700667A NL7700667A (nl) | 1976-01-21 | 1977-01-21 | Werkwijze ter bereiding van nieuwe gesubstitu- eerde indoolverbindingen. |
| US05/904,328 US4233312A (en) | 1976-01-21 | 1978-05-09 | Esters of indole-1-acetic acid and analgesic use thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7629652A FR2366016A2 (fr) | 1976-10-01 | 1976-10-01 | Nouveaux indoles substitues, leur procede de preparation et leur application comme medicament |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2366016A2 true FR2366016A2 (fr) | 1978-04-28 |
| FR2366016B2 FR2366016B2 (enrdf_load_stackoverflow) | 1980-09-12 |
Family
ID=9178307
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7629652A Granted FR2366016A2 (fr) | 1976-01-21 | 1976-10-01 | Nouveaux indoles substitues, leur procede de preparation et leur application comme medicament |
Country Status (1)
| Country | Link |
|---|---|
| FR (1) | FR2366016A2 (enrdf_load_stackoverflow) |
-
1976
- 1976-10-01 FR FR7629652A patent/FR2366016A2/fr active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| FR2366016B2 (enrdf_load_stackoverflow) | 1980-09-12 |
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