FR2365347A2 - Nouvelle hormone polypeptide possedant une activite thymique et son procede de preparation - Google Patents
Nouvelle hormone polypeptide possedant une activite thymique et son procede de preparationInfo
- Publication number
- FR2365347A2 FR2365347A2 FR7707624A FR7707624A FR2365347A2 FR 2365347 A2 FR2365347 A2 FR 2365347A2 FR 7707624 A FR7707624 A FR 7707624A FR 7707624 A FR7707624 A FR 7707624A FR 2365347 A2 FR2365347 A2 FR 2365347A2
- Authority
- FR
- France
- Prior art keywords
- factor polypeptide
- blood
- polypeptide hormone
- selective
- recovered
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 208000023275 Autoimmune disease Diseases 0.000 title abstract 2
- 102000015731 Peptide Hormones Human genes 0.000 title abstract 2
- 108010038988 Peptide Hormones Proteins 0.000 title abstract 2
- 210000001744 T-lymphocyte Anatomy 0.000 title abstract 2
- 239000008280 blood Substances 0.000 title abstract 2
- 210000004369 blood Anatomy 0.000 title abstract 2
- 239000000813 peptide hormone Substances 0.000 title abstract 2
- 230000000638 stimulation Effects 0.000 title abstract 2
- 210000001541 thymus gland Anatomy 0.000 title abstract 2
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 abstract 3
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 abstract 3
- HEDRZPFGACZZDS-UHFFFAOYSA-N Chloroform Chemical compound ClC(Cl)Cl HEDRZPFGACZZDS-UHFFFAOYSA-N 0.000 abstract 2
- JVIPLYCGEZUBIO-UHFFFAOYSA-N 2-(4-fluorophenyl)-1,3-dioxoisoindole-5-carboxylic acid Chemical group O=C1C2=CC(C(=O)O)=CC=C2C(=O)N1C1=CC=C(F)C=C1 JVIPLYCGEZUBIO-UHFFFAOYSA-N 0.000 abstract 1
- VHUUQVKOLVNVRT-UHFFFAOYSA-N Ammonium hydroxide Chemical compound [NH4+].[OH-] VHUUQVKOLVNVRT-UHFFFAOYSA-N 0.000 abstract 1
- 229920002134 Carboxymethyl cellulose Polymers 0.000 abstract 1
- 229920001425 Diethylaminoethyl cellulose Polymers 0.000 abstract 1
- 229920005654 Sephadex Polymers 0.000 abstract 1
- 239000012507 Sephadex™ Substances 0.000 abstract 1
- 235000011114 ammonium hydroxide Nutrition 0.000 abstract 1
- -1 aromatic amino acids Chemical class 0.000 abstract 1
- 229920002678 cellulose Polymers 0.000 abstract 1
- 239000001913 cellulose Substances 0.000 abstract 1
- 239000003610 charcoal Substances 0.000 abstract 1
- 238000004587 chromatography analysis Methods 0.000 abstract 1
- 238000000502 dialysis Methods 0.000 abstract 1
- 239000012153 distilled water Substances 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 238000010255 intramuscular injection Methods 0.000 abstract 1
- 239000007927 intramuscular injection Substances 0.000 abstract 1
- 238000010253 intravenous injection Methods 0.000 abstract 1
- 206010025135 lupus erythematosus Diseases 0.000 abstract 1
- 239000012528 membrane Substances 0.000 abstract 1
- 238000005374 membrane filtration Methods 0.000 abstract 1
- 239000002808 molecular sieve Substances 0.000 abstract 1
- 239000008363 phosphate buffer Substances 0.000 abstract 1
- 229920002239 polyacrylonitrile Polymers 0.000 abstract 1
- URGAHOPLAPQHLN-UHFFFAOYSA-N sodium aluminosilicate Chemical compound [Na+].[Al+3].[O-][Si]([O-])=O.[O-][Si]([O-])=O URGAHOPLAPQHLN-UHFFFAOYSA-N 0.000 abstract 1
- 239000007787 solid Substances 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
- C07K7/062—Serum thymic factor
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Endocrinology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7707624A FR2365347A2 (fr) | 1976-09-22 | 1977-03-15 | Nouvelle hormone polypeptide possedant une activite thymique et son procede de preparation |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US05/725,594 US4133804A (en) | 1974-03-25 | 1976-09-22 | Polypeptide possessing thymic activity |
| FR7707624A FR2365347A2 (fr) | 1976-09-22 | 1977-03-15 | Nouvelle hormone polypeptide possedant une activite thymique et son procede de preparation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2365347A2 true FR2365347A2 (fr) | 1978-04-21 |
| FR2365347B2 FR2365347B2 (enrdf_load_stackoverflow) | 1982-01-15 |
Family
ID=26219910
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7707624A Granted FR2365347A2 (fr) | 1976-09-22 | 1977-03-15 | Nouvelle hormone polypeptide possedant une activite thymique et son procede de preparation |
Country Status (1)
| Country | Link |
|---|---|
| FR (1) | FR2365347A2 (enrdf_load_stackoverflow) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2513125A1 (fr) * | 1981-09-22 | 1983-03-25 | Mitsui Pharmaceuticals | Medicament curatif du deficit immunitaire |
-
1977
- 1977-03-15 FR FR7707624A patent/FR2365347A2/fr active Granted
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2513125A1 (fr) * | 1981-09-22 | 1983-03-25 | Mitsui Pharmaceuticals | Medicament curatif du deficit immunitaire |
Also Published As
| Publication number | Publication date |
|---|---|
| FR2365347B2 (enrdf_load_stackoverflow) | 1982-01-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| TP | Transmission of property |