FR2360549A1 - Composes intermediaires pour la synthese d'antibiotiques quinoniques polycycliques, et procede de preparation de ces antibiotiques - Google Patents

Composes intermediaires pour la synthese d'antibiotiques quinoniques polycycliques, et procede de preparation de ces antibiotiques

Info

Publication number
FR2360549A1
FR2360549A1 FR7634663A FR7634663A FR2360549A1 FR 2360549 A1 FR2360549 A1 FR 2360549A1 FR 7634663 A FR7634663 A FR 7634663A FR 7634663 A FR7634663 A FR 7634663A FR 2360549 A1 FR2360549 A1 FR 2360549A1
Authority
FR
France
Prior art keywords
antibiotics
synthesis
polycyclic
quinonic
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7634663A
Other languages
English (en)
Other versions
FR2360549B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Research Corp
Original Assignee
Research Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/632,939 external-priority patent/US4070382A/en
Application filed by Research Corp filed Critical Research Corp
Publication of FR2360549A1 publication Critical patent/FR2360549A1/fr
Application granted granted Critical
Publication of FR2360549B1 publication Critical patent/FR2360549B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C46/00—Preparation of quinones
    • C07C46/02—Preparation of quinones by oxidation giving rise to quinoid structures
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C46/00—Preparation of quinones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C46/00—Preparation of quinones
    • C07C46/02—Preparation of quinones by oxidation giving rise to quinoid structures
    • C07C46/06—Preparation of quinones by oxidation giving rise to quinoid structures of at least one hydroxy group on a six-membered aromatic ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

L'invention concerne des composés intermédiaires pour la synthèse d'antibiotiques quinoniques polycycliques, et procédé de préparation de ces antibiotiques. Selon le procédé de l'invention on soumet un dérivé de 1,4,5,8-hydroxy-anthraquinone à une oxydation. Application à la synthèse d'analogues de la ( +- )-7-désoxydaunomycinone à propriétés anti-néoplastiques.
FR7634663A 1975-11-18 1976-11-17 Composes intermediaires pour la synthese d'antibiotiques quinoniques polycycliques, et procede de preparation de ces antibiotiques Granted FR2360549A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US05/632,939 US4070382A (en) 1975-11-18 1975-11-18 Intermediates for polycyclic quinoid antibiotics
US05/673,513 US4021457A (en) 1975-11-18 1976-04-05 Intermediates for polycyclic quinonoid antibiotics

Publications (2)

Publication Number Publication Date
FR2360549A1 true FR2360549A1 (fr) 1978-03-03
FR2360549B1 FR2360549B1 (fr) 1980-12-05

Family

ID=27091763

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7634663A Granted FR2360549A1 (fr) 1975-11-18 1976-11-17 Composes intermediaires pour la synthese d'antibiotiques quinoniques polycycliques, et procede de preparation de ces antibiotiques

Country Status (5)

Country Link
US (1) US4021457A (fr)
DD (1) DD130575A5 (fr)
DE (1) DE2651201A1 (fr)
FR (1) FR2360549A1 (fr)
GB (1) GB1570082A (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4089872A (en) * 1977-03-09 1978-05-16 The Upjohn Company Antibiotics steffimycinol and 7-deoxysteffimycinol and process for preparing the same
US4196127A (en) * 1978-06-01 1980-04-01 Research Corporation Anthracyclines
US4244880A (en) * 1978-06-05 1981-01-13 University Of Kansas Endowment Association Anthracycline synthesis
US4164503A (en) * 1978-10-10 1979-08-14 Research Corporation Quinonoid intermediates from chloroprene
US4405522A (en) * 1982-01-18 1983-09-20 Adria Laboratories Inc. Anthracycline synthesis
BE896743A (fr) * 1982-08-13 1983-09-16 Erba Farmitalia Synthese de naphtacenequinone.
GB8708927D0 (en) * 1987-04-14 1987-05-20 Erba Farmitalia Chiral synthesis of anthracyclines
NZ224252A (en) * 1987-04-21 1991-09-25 Erba Carlo Spa An anthracycline glycoside and its preparation

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH470334A (de) * 1965-01-14 1969-03-31 Sandoz Ag Verfahren zur Herstellung von polycyclischen chinoiden Verbindungen
FR7785M (fr) * 1968-10-07 1970-03-23
CH514530A (de) * 1965-01-15 1971-10-31 Sandoz Ag Verfahren zur Herstellung von polycyclischen chinoiden Verbindungen

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2922691A (en) * 1955-08-02 1960-01-26 Ciba Ltd Anthraquinone dyes and polyethylene terephthalate fibers dyed therewith
CH350396A (de) * 1956-07-17 1960-11-30 Ciba Geigy Verfahren zur Herstellung neuer Farbstoffe der Anthrachinonreihe
GB1357985A (en) * 1972-02-18 1974-06-26 Ici Ltd Anthraquinone compounds

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH470334A (de) * 1965-01-14 1969-03-31 Sandoz Ag Verfahren zur Herstellung von polycyclischen chinoiden Verbindungen
CH514530A (de) * 1965-01-15 1971-10-31 Sandoz Ag Verfahren zur Herstellung von polycyclischen chinoiden Verbindungen
FR7785M (fr) * 1968-10-07 1970-03-23

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
NV6013/76 *

Also Published As

Publication number Publication date
GB1570082A (en) 1980-06-25
DD130575A5 (de) 1978-04-12
DE2651201A1 (de) 1977-06-02
FR2360549B1 (fr) 1980-12-05
US4021457A (en) 1977-05-03

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Legal Events

Date Code Title Description
ST Notification of lapse