FR2359837A1 - NEW THIOPHENE DERIVATIVES WITH ANTI-INFLAMMATORY ACTIVITY - Google Patents

NEW THIOPHENE DERIVATIVES WITH ANTI-INFLAMMATORY ACTIVITY

Info

Publication number
FR2359837A1
FR2359837A1 FR7722739A FR7722739A FR2359837A1 FR 2359837 A1 FR2359837 A1 FR 2359837A1 FR 7722739 A FR7722739 A FR 7722739A FR 7722739 A FR7722739 A FR 7722739A FR 2359837 A1 FR2359837 A1 FR 2359837A1
Authority
FR
France
Prior art keywords
inflammatory activity
thiophene derivatives
new thiophene
new
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7722739A
Other languages
French (fr)
Other versions
FR2359837B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beecham Group PLC
Original Assignee
Beecham Group PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Group PLC filed Critical Beecham Group PLC
Publication of FR2359837A1 publication Critical patent/FR2359837A1/en
Application granted granted Critical
Publication of FR2359837B1 publication Critical patent/FR2359837B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/22—Radicals substituted by doubly bound hetero atoms, or by two hetero atoms other than halogen singly bound to the same carbon atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/673—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by change of size of the carbon skeleton

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Rheumatology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)

Abstract

Cette invention concerne de nouveaux dérivés du thiophène. Ces dérivés répondent à la formule :This invention relates to novel thiophene derivatives. These derivatives correspond to the formula:

FR7722739A 1976-07-30 1977-07-25 NEW THIOPHENE DERIVATIVES WITH ANTI-INFLAMMATORY ACTIVITY Granted FR2359837A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB31852/76A GB1525434A (en) 1976-07-30 1976-07-30 Anti-inflammatory thiophene derivatives

Publications (2)

Publication Number Publication Date
FR2359837A1 true FR2359837A1 (en) 1978-02-24
FR2359837B1 FR2359837B1 (en) 1980-04-04

Family

ID=10329363

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7722739A Granted FR2359837A1 (en) 1976-07-30 1977-07-25 NEW THIOPHENE DERIVATIVES WITH ANTI-INFLAMMATORY ACTIVITY

Country Status (16)

Country Link
JP (1) JPS5318558A (en)
AT (1) AT361466B (en)
AU (1) AU507121B2 (en)
BE (1) BE857128A (en)
CA (1) CA1078400A (en)
CH (1) CH636613A5 (en)
DE (1) DE2733683A1 (en)
DK (1) DK339877A (en)
ES (1) ES461037A1 (en)
FR (1) FR2359837A1 (en)
GB (1) GB1525434A (en)
IE (1) IE45325B1 (en)
IL (1) IL52503A (en)
NL (1) NL7708062A (en)
SE (1) SE7708591L (en)
ZA (1) ZA774222B (en)

Also Published As

Publication number Publication date
GB1525434A (en) 1978-09-20
AT361466B (en) 1981-03-10
SE7708591L (en) 1978-01-31
CA1078400A (en) 1980-05-27
IE45325L (en) 1978-01-30
BE857128A (en) 1978-01-25
NL7708062A (en) 1978-02-01
ATA560477A (en) 1980-08-15
ES461037A1 (en) 1978-12-01
DE2733683A1 (en) 1978-02-02
ZA774222B (en) 1978-06-28
AU2747177A (en) 1979-02-01
DK339877A (en) 1978-01-31
IE45325B1 (en) 1982-07-28
CH636613A5 (en) 1983-06-15
IL52503A0 (en) 1977-10-31
IL52503A (en) 1981-06-29
AU507121B2 (en) 1980-02-07
JPS5318558A (en) 1978-02-20
FR2359837B1 (en) 1980-04-04

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Legal Events

Date Code Title Description
ST Notification of lapse