FR2351653A1 - (4)-Hydroxy-(1)-thio-coumarin derivs. - for use as anticoagulant medicaments - Google Patents

(4)-Hydroxy-(1)-thio-coumarin derivs. - for use as anticoagulant medicaments

Info

Publication number
FR2351653A1
FR2351653A1 FR7615532A FR7615532A FR2351653A1 FR 2351653 A1 FR2351653 A1 FR 2351653A1 FR 7615532 A FR7615532 A FR 7615532A FR 7615532 A FR7615532 A FR 7615532A FR 2351653 A1 FR2351653 A1 FR 2351653A1
Authority
FR
France
Prior art keywords
derivs
hydroxy
coumarin
thio
thiocoumarin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
FR7615532A
Other languages
French (fr)
Inventor
Tamara Viktorovna Smirnova
Galina Mikhailovna Vishnyakova
Jury Alexandrovich Strepikheev
Tatyana Sergeevna Simonenko
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
MO KHIM T
Original Assignee
MO KHIM T
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by MO KHIM T filed Critical MO KHIM T
Priority to FR7615532A priority Critical patent/FR2351653A1/en
Publication of FR2351653A1 publication Critical patent/FR2351653A1/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D335/00—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
    • C07D335/04—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D335/06—Benzothiopyrans; Hydrogenated benzothiopyrans

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

New 4-hydroxy-1-thiocoumarin derivs. have formula (I): (where X is H, Cl, Br or NO2). Cpds. (I) are anticoagulants with higher activity, a shorter latent period (18-36 hr.), less side-effects and lower toxicity than the corresp. 4-hydroxycoumarin derivs. They can be used, e.g., in the treatment of thrombosis, thrombophlebitis and heart disease. In an example, (I; X = H) is prepd. from 4-hydroxy-1-thiocoumarin and 1-phenyl-1-penten-3-one.
FR7615532A 1976-05-21 1976-05-21 (4)-Hydroxy-(1)-thio-coumarin derivs. - for use as anticoagulant medicaments Withdrawn FR2351653A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR7615532A FR2351653A1 (en) 1976-05-21 1976-05-21 (4)-Hydroxy-(1)-thio-coumarin derivs. - for use as anticoagulant medicaments

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7615532A FR2351653A1 (en) 1976-05-21 1976-05-21 (4)-Hydroxy-(1)-thio-coumarin derivs. - for use as anticoagulant medicaments

Publications (1)

Publication Number Publication Date
FR2351653A1 true FR2351653A1 (en) 1977-12-16

Family

ID=9173504

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7615532A Withdrawn FR2351653A1 (en) 1976-05-21 1976-05-21 (4)-Hydroxy-(1)-thio-coumarin derivs. - for use as anticoagulant medicaments

Country Status (1)

Country Link
FR (1) FR2351653A1 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0161163A1 (en) * 1984-04-12 1985-11-13 Lipha, Lyonnaise Industrielle Pharmaceutique 4-Hydroxy-2H-1-benzothiopyran-2-one derivatives, their preparation and uses

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0161163A1 (en) * 1984-04-12 1985-11-13 Lipha, Lyonnaise Industrielle Pharmaceutique 4-Hydroxy-2H-1-benzothiopyran-2-one derivatives, their preparation and uses

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Legal Events

Date Code Title Description
ST Notification of lapse