FR2340732A1 - Nouvelles compositions anti-hypertensives contenant des derives d'alanine - Google Patents

Nouvelles compositions anti-hypertensives contenant des derives d'alanine

Info

Publication number
FR2340732A1
FR2340732A1 FR7703909A FR7703909A FR2340732A1 FR 2340732 A1 FR2340732 A1 FR 2340732A1 FR 7703909 A FR7703909 A FR 7703909A FR 7703909 A FR7703909 A FR 7703909A FR 2340732 A1 FR2340732 A1 FR 2340732A1
Authority
FR
France
Prior art keywords
compositions containing
new anti
alanine derivatives
containing alanine
hypertensive compositions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7703909A
Other languages
English (en)
French (fr)
Other versions
FR2340732B1 (OSRAM
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of FR2340732A1 publication Critical patent/FR2340732A1/fr
Application granted granted Critical
Publication of FR2340732B1 publication Critical patent/FR2340732B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
    • C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
    • C07D263/58—Benzoxazoles; Hydrogenated benzoxazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/26—Oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
FR7703909A 1976-02-13 1977-02-11 Nouvelles compositions anti-hypertensives contenant des derives d'alanine Granted FR2340732A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/657,824 US4051251A (en) 1976-02-13 1976-02-13 Novel anti-hypertensive compositions

Publications (2)

Publication Number Publication Date
FR2340732A1 true FR2340732A1 (fr) 1977-09-09
FR2340732B1 FR2340732B1 (OSRAM) 1979-08-24

Family

ID=24638794

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7703909A Granted FR2340732A1 (fr) 1976-02-13 1977-02-11 Nouvelles compositions anti-hypertensives contenant des derives d'alanine

Country Status (10)

Country Link
US (2) US4051251A (OSRAM)
JP (1) JPS5299225A (OSRAM)
AU (1) AU513541B2 (OSRAM)
BE (1) BE851052A (OSRAM)
DE (1) DE2705883A1 (OSRAM)
FR (1) FR2340732A1 (OSRAM)
GB (1) GB1526172A (OSRAM)
NL (1) NL7700944A (OSRAM)
NZ (1) NZ183226A (OSRAM)
ZA (1) ZA77814B (OSRAM)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2381032A1 (fr) * 1977-02-17 1978-09-15 Merck & Co Inc Nouvelles anilines substituees a activite antihypertensive

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4401676A (en) * 1977-06-01 1983-08-30 Merck & Co., Inc. Novel α-amino acids
WO2004052841A1 (en) * 2002-12-06 2004-06-24 Xenoport, Inc. Carbidopa prodrugs and uses thereof

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2113949A1 (en) * 1970-11-12 1972-06-30 Merck & Co Inc Compsns contg l-dopa and an alpha hydrazinyl propionic - acid - for treatment of hypertension

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3462536A (en) * 1960-07-22 1969-08-19 Merck & Co Inc Method of inhibiting decarboxylase
US3839585A (en) * 1970-08-05 1974-10-01 Merck & Co Inc Method of treating hypertension

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2113949A1 (en) * 1970-11-12 1972-06-30 Merck & Co Inc Compsns contg l-dopa and an alpha hydrazinyl propionic - acid - for treatment of hypertension

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2381032A1 (fr) * 1977-02-17 1978-09-15 Merck & Co Inc Nouvelles anilines substituees a activite antihypertensive

Also Published As

Publication number Publication date
ZA77814B (en) 1978-09-27
US4051251A (en) 1977-09-27
US4069333A (en) 1978-01-17
JPS5299225A (en) 1977-08-19
BE851052A (fr) 1977-08-03
NL7700944A (nl) 1977-08-16
AU2191977A (en) 1978-08-10
NZ183226A (en) 1980-03-05
GB1526172A (en) 1978-09-27
AU513541B2 (en) 1980-12-11
FR2340732B1 (OSRAM) 1979-08-24
DE2705883A1 (de) 1977-08-18

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Legal Events

Date Code Title Description
ST Notification of lapse