FR2337725A1 - Derives heterocycliques de l'ergoline inhibant l'agregation des plaquettes sanguines et procede pour les preparer - Google Patents
Derives heterocycliques de l'ergoline inhibant l'agregation des plaquettes sanguines et procede pour les preparerInfo
- Publication number
- FR2337725A1 FR2337725A1 FR7700336A FR7700336A FR2337725A1 FR 2337725 A1 FR2337725 A1 FR 2337725A1 FR 7700336 A FR7700336 A FR 7700336A FR 7700336 A FR7700336 A FR 7700336A FR 2337725 A1 FR2337725 A1 FR 2337725A1
- Authority
- FR
- France
- Prior art keywords
- heterocyclical
- ergoline
- aggregation
- inhibiting
- derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- AWFDCTXCTHGORH-HGHGUNKESA-N 6-[4-[(6ar,9r,10ar)-5-bromo-7-methyl-6,6a,8,9,10,10a-hexahydro-4h-indolo[4,3-fg]quinoline-9-carbonyl]piperazin-1-yl]-1-methylpyridin-2-one Chemical class O=C([C@H]1CN([C@H]2[C@@H](C=3C=CC=C4NC(Br)=C(C=34)C2)C1)C)N(CC1)CCN1C1=CC=CC(=O)N1C AWFDCTXCTHGORH-HGHGUNKESA-N 0.000 title 1
- 238000004220 aggregation Methods 0.000 title 1
- 230000002776 aggregation Effects 0.000 title 1
- 239000008280 blood Substances 0.000 title 1
- 210000004369 blood Anatomy 0.000 title 1
- 230000002401 inhibitory effect Effects 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
- C07D457/02—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hydrocarbon or substituted hydrocarbon radicals, attached in position 8
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Hematology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB738/76A GB1513322A (en) | 1976-01-09 | 1976-01-09 | Heterocyclic ergoline derivatives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2337725A1 true FR2337725A1 (fr) | 1977-08-05 |
| FR2337725B1 FR2337725B1 (enExample) | 1980-03-14 |
Family
ID=9709660
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7700336A Granted FR2337725A1 (fr) | 1976-01-09 | 1977-01-07 | Derives heterocycliques de l'ergoline inhibant l'agregation des plaquettes sanguines et procede pour les preparer |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US4089862A (enExample) |
| JP (1) | JPS5287199A (enExample) |
| CH (1) | CH627466A5 (enExample) |
| DE (1) | DE2700276A1 (enExample) |
| FR (1) | FR2337725A1 (enExample) |
| GB (1) | GB1513322A (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU526764B2 (en) * | 1978-09-08 | 1983-01-27 | Farmitalia Carlo Erba S.P.A. | Ergoline derivatives |
| IT1173489B (it) * | 1984-03-27 | 1987-06-24 | Inverni Della Beffa Spa | Procedimento di preparazione di 1-metil-10alfa-metossilumilisergolo e di suci esteri,e intermedi per la loro preparazione |
| HU193782B (en) * | 1985-06-21 | 1987-11-30 | Richter Gedeon Vegyeszet | Process for producing 2-halogeno-nicergoline derivatives and acid additional salts thereof |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3014909A (en) * | 1961-12-26 | New basically substituted g-methyx- | ||
| NL278401A (enExample) * | 1961-05-29 | |||
| CH463524A (de) * | 1965-08-16 | 1968-10-15 | Sandoz Ag | Verfahren zur Herstellung von neuen Lysergsäurederivaten |
| NL7303428A (enExample) * | 1972-03-17 | 1973-09-19 | ||
| CA990287A (en) * | 1972-09-26 | 1976-06-01 | Sandoz Patents Limited | 13-bromo-lysergic acid compounds |
| US3996228A (en) * | 1973-12-21 | 1976-12-07 | Societa' Farmaceutici Italia S.P.A. | Pyrimidinoaminoethyl ergoline derivatives |
| US4004011A (en) * | 1974-04-16 | 1977-01-18 | Sandoz Ltd. | 3-Pyridylamine substituted ergolines |
-
1976
- 1976-01-09 GB GB738/76A patent/GB1513322A/en not_active Expired
-
1977
- 1977-01-04 US US05/756,725 patent/US4089862A/en not_active Expired - Lifetime
- 1977-01-05 DE DE19772700276 patent/DE2700276A1/de not_active Withdrawn
- 1977-01-07 FR FR7700336A patent/FR2337725A1/fr active Granted
- 1977-01-07 JP JP71077A patent/JPS5287199A/ja active Pending
- 1977-01-07 CH CH21177A patent/CH627466A5/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| FR2337725B1 (enExample) | 1980-03-14 |
| GB1513322A (en) | 1978-06-07 |
| DE2700276A1 (de) | 1977-08-18 |
| CH627466A5 (de) | 1982-01-15 |
| JPS5287199A (en) | 1977-07-20 |
| US4089862A (en) | 1978-05-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |