FR2336134A1 - TRIFLUOROMETHYLTHIO DERIVATIVES OF CYPROHEPTADINE USEFUL AS A MEDICINAL PRODUCT - Google Patents

TRIFLUOROMETHYLTHIO DERIVATIVES OF CYPROHEPTADINE USEFUL AS A MEDICINAL PRODUCT

Info

Publication number
FR2336134A1
FR2336134A1 FR7637941A FR7637941A FR2336134A1 FR 2336134 A1 FR2336134 A1 FR 2336134A1 FR 7637941 A FR7637941 A FR 7637941A FR 7637941 A FR7637941 A FR 7637941A FR 2336134 A1 FR2336134 A1 FR 2336134A1
Authority
FR
France
Prior art keywords
cyproheptadine
trifluoromethylthio
derivatives
useful
medicinal product
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7637941A
Other languages
French (fr)
Other versions
FR2336134B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of FR2336134A1 publication Critical patent/FR2336134A1/en
Application granted granted Critical
Publication of FR2336134B1 publication Critical patent/FR2336134B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
    • C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
FR7637941A 1975-12-22 1976-12-16 TRIFLUOROMETHYLTHIO DERIVATIVES OF CYPROHEPTADINE USEFUL AS A MEDICINAL PRODUCT Granted FR2336134A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/642,864 US4031223A (en) 1975-12-22 1975-12-22 Trifluoromethylthio derivatives of cyproheptadine

Publications (2)

Publication Number Publication Date
FR2336134A1 true FR2336134A1 (en) 1977-07-22
FR2336134B1 FR2336134B1 (en) 1980-06-20

Family

ID=24578359

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7637941A Granted FR2336134A1 (en) 1975-12-22 1976-12-16 TRIFLUOROMETHYLTHIO DERIVATIVES OF CYPROHEPTADINE USEFUL AS A MEDICINAL PRODUCT

Country Status (9)

Country Link
US (1) US4031223A (en)
JP (1) JPS5287177A (en)
CH (1) CH625789A5 (en)
DE (1) DE2657950A1 (en)
DK (1) DK551076A (en)
FR (1) FR2336134A1 (en)
GB (1) GB1522238A (en)
NL (1) NL7613714A (en)
SE (1) SE428923B (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0012988B1 (en) * 1979-01-02 1983-04-27 Merck & Co. Inc. Levorotatory or dextrorotatory enantiomers of 3-halocyproheptadines, process for their preparation and pharmaceutical composition thereof
US4220651A (en) * 1979-05-21 1980-09-02 Merck & Co., Inc. Antipsychotic levorotatory enantiomers of 3-halocyproheptadines, analogs and derivatives
EP0019797A1 (en) * 1979-05-21 1980-12-10 Merck & Co. Inc. Levorotatory and dextrorotatory enantiomers of 3-methoxycyproheptadine and analogs thereof, process for their preparation and antipsychotic pharmaceutical compositions
US4390436A (en) 1982-02-08 1983-06-28 S. C. Johnson & Son, Inc. Aqueous film forming lubricant useful in a method for drawing aluminum and other soft metals
US5114919A (en) * 1990-02-26 1992-05-19 Merck & Co., Inc. Adjuncts in cancer chemotherapy
AU6230398A (en) 1997-02-27 1998-09-18 Ajinomoto Co., Inc. Thrombolytic agent

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3851059A (en) * 1970-02-05 1974-11-26 Merck & Co Inc Method for the stimulation of appetite in patients

Also Published As

Publication number Publication date
GB1522238A (en) 1978-08-23
NL7613714A (en) 1977-06-24
DE2657950A1 (en) 1977-06-30
SE7613797L (en) 1977-06-23
SE428923B (en) 1983-08-01
JPS5287177A (en) 1977-07-20
CH625789A5 (en) 1981-10-15
DK551076A (en) 1977-06-23
US4031223A (en) 1977-06-21
FR2336134B1 (en) 1980-06-20

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Legal Events

Date Code Title Description
ST Notification of lapse