FR2321296A1 - Broad-spectrum antibacterials from nocardia sp. NRRL 5646 - sepd. into five BM 123 alpha-gamma cpds. - Google Patents

Broad-spectrum antibacterials from nocardia sp. NRRL 5646 - sepd. into five BM 123 alpha-gamma cpds.

Info

Publication number
FR2321296A1
FR2321296A1 FR7625242A FR7625242A FR2321296A1 FR 2321296 A1 FR2321296 A1 FR 2321296A1 FR 7625242 A FR7625242 A FR 7625242A FR 7625242 A FR7625242 A FR 7625242A FR 2321296 A1 FR2321296 A1 FR 2321296A1
Authority
FR
France
Prior art keywords
nocardia
nrrl
cpds
alpha
broad
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7625242A
Other languages
French (fr)
Other versions
FR2321296B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth Holdings LLC
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/606,634 external-priority patent/US4007167A/en
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Publication of FR2321296A1 publication Critical patent/FR2321296A1/en
Application granted granted Critical
Publication of FR2321296B1 publication Critical patent/FR2321296B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/203—Monocyclic carbocyclic rings other than cyclohexane rings; Bicyclic carbocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

Antibiotics BM 123 alpha, 123 beta1, 123 gamma1 and 123 gamma2 of formulae (I) and (IIa)-(IIc), respectively, and their acid-addn. salts, are new: (where X is: The cpds. are antibacterials with a broad spectrum of activity, e.g., with high activity in mice against Proteus mirabilis, Kl. pneumoniae and E. coli strains. Antibiotics (I) and (II) were obtd. by cultivation of Nocardia sp. NRRL 5646 .
FR7625242A 1975-08-21 1976-08-19 Broad-spectrum antibacterials from nocardia sp. NRRL 5646 - sepd. into five BM 123 alpha-gamma cpds. Granted FR2321296A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/606,634 US4007167A (en) 1974-10-09 1975-08-21 Antibiotic BM123 and production thereof

Publications (2)

Publication Number Publication Date
FR2321296A1 true FR2321296A1 (en) 1977-03-18
FR2321296B1 FR2321296B1 (en) 1979-01-12

Family

ID=24428797

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7625242A Granted FR2321296A1 (en) 1975-08-21 1976-08-19 Broad-spectrum antibacterials from nocardia sp. NRRL 5646 - sepd. into five BM 123 alpha-gamma cpds.

Country Status (6)

Country Link
JP (1) JPS5225089A (en)
BE (1) BE845336A (en)
CA (1) CA1087537A (en)
DE (1) DE2637545A1 (en)
FR (1) FR2321296A1 (en)
ZA (1) ZA764338B (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1982000464A1 (en) * 1980-07-28 1982-02-18 Loibner H Guanylated aminoglycosides,a process for their production and their use as pharmaceuticals

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2202680A1 (en) * 1972-10-12 1974-05-10 American Cyanamid Co
FR2293212A1 (en) * 1974-12-05 1976-07-02 American Cyanamid Co NEW ANTIBIOTICS AND THEIR PREPARATION PROCESS

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2202680A1 (en) * 1972-10-12 1974-05-10 American Cyanamid Co
FR2293212A1 (en) * 1974-12-05 1976-07-02 American Cyanamid Co NEW ANTIBIOTICS AND THEIR PREPARATION PROCESS

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1982000464A1 (en) * 1980-07-28 1982-02-18 Loibner H Guanylated aminoglycosides,a process for their production and their use as pharmaceuticals

Also Published As

Publication number Publication date
CA1087537A (en) 1980-10-14
JPS5442981B2 (en) 1979-12-17
DE2637545B2 (en) 1979-10-18
ZA764338B (en) 1977-07-27
DE2637545A1 (en) 1977-03-03
FR2321296B1 (en) 1979-01-12
JPS5225089A (en) 1977-02-24
DE2637545C3 (en) 1980-07-03
BE845336A (en) 1977-02-21

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Legal Events

Date Code Title Description
ST Notification of lapse