FR2319340A1 - Nouveau sel de l'acide a-methyl benzoyl-5 thiophene-2 acetique, procede de preparation et application a titre de medicament - Google Patents

Nouveau sel de l'acide a-methyl benzoyl-5 thiophene-2 acetique, procede de preparation et application a titre de medicament

Info

Publication number
FR2319340A1
FR2319340A1 FR7523501A FR7523501A FR2319340A1 FR 2319340 A1 FR2319340 A1 FR 2319340A1 FR 7523501 A FR7523501 A FR 7523501A FR 7523501 A FR7523501 A FR 7523501A FR 2319340 A1 FR2319340 A1 FR 2319340A1
Authority
FR
France
Prior art keywords
thiophene
preparation
acetic acid
application
medicinal product
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7523501A
Other languages
English (en)
French (fr)
Other versions
FR2319340B1 (nl
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Roussel Uclaf SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf SA filed Critical Roussel Uclaf SA
Priority to FR7523501A priority Critical patent/FR2319340A1/fr
Priority to US05/705,057 priority patent/US4318918A/en
Priority to CA257,904A priority patent/CA1068286A/en
Priority to LU75469A priority patent/LU75469A1/xx
Priority to BE169274A priority patent/BE844557A/xx
Priority to IE1676/76A priority patent/IE43929B1/en
Priority to CH968576A priority patent/CH601285A5/xx
Priority to GB31376/76A priority patent/GB1488778A/en
Priority to JP51089274A priority patent/JPS5217462A/ja
Priority to NLAANVRAGE7608360,A priority patent/NL186005C/nl
Priority to DE2633891A priority patent/DE2633891C2/de
Priority to DK338576A priority patent/DK145420C/da
Publication of FR2319340A1 publication Critical patent/FR2319340A1/fr
Application granted granted Critical
Publication of FR2319340B1 publication Critical patent/FR2319340B1/fr
Priority to IT7949862A priority patent/IT7949862A0/it
Granted legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/205Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/38Heterocyclic compounds having sulfur as a ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
FR7523501A 1975-07-28 1975-07-28 Nouveau sel de l'acide a-methyl benzoyl-5 thiophene-2 acetique, procede de preparation et application a titre de medicament Granted FR2319340A1 (fr)

Priority Applications (13)

Application Number Priority Date Filing Date Title
FR7523501A FR2319340A1 (fr) 1975-07-28 1975-07-28 Nouveau sel de l'acide a-methyl benzoyl-5 thiophene-2 acetique, procede de preparation et application a titre de medicament
US05/705,057 US4318918A (en) 1975-07-28 1976-07-14 Novel salt of 5-(benzoyl)-thiophene-2-α-methyl-acetic acid
LU75469A LU75469A1 (nl) 1975-07-28 1976-07-27
BE169274A BE844557A (fr) 1975-07-28 1976-07-27 Nouveau sel de l'acide &-methyle benzoyl-5 thiophene-2 acetique, procede de preparation et compositions pharmaceutiques
CA257,904A CA1068286A (en) 1975-07-28 1976-07-27 Process for the preparation of a novel-methyl-5-benzoyl-2-thiophene acetic acid salt
CH968576A CH601285A5 (nl) 1975-07-28 1976-07-28
IE1676/76A IE43929B1 (en) 1975-07-28 1976-07-28 A new salt of a-methyl-(5-benzoyl-2-thiophene)-acetic acid processes for preparing it and compositions containing them
GB31376/76A GB1488778A (en) 1975-07-28 1976-07-28 Salt of alpha-methyl-(5-benzoyl-2-thiophene)-acetic acid processes for preparing it and compositions containing it
JP51089274A JPS5217462A (en) 1975-07-28 1976-07-28 Production of alphaamethyll55 benzoylthiophenee22acetic acid * novel salt thereof and pharmaceutical composition
NLAANVRAGE7608360,A NL186005C (nl) 1975-07-28 1976-07-28 Werkwijze voor de bereiding van een preparaat dat een zout van 2-(5-benzoylthiofenyl-2)propionzuur bevat en werkwijze voor de bereiding van het hiervoor te gebruiken zout.
DE2633891A DE2633891C2 (de) 1975-07-28 1976-07-28 Tris-(hydroxymethyl)-aminomethansalz der 2-(5-Benzoylthienyl)-α-methylessigsäure, Verfahren zu dessen Herstellung und dieses enthaltende pharmazeutische Zusammensetzungen
DK338576A DK145420C (da) 1975-07-28 1976-07-28 Analogifremgangsmaade til fremstilling af alfa-methyl-5-benzoyl-2-thiophenacetatet af tromethamin
IT7949862A IT7949862A0 (it) 1975-07-28 1979-07-25 Procedimento per la preparazione del sale trometamminico dell'acido alfa-metil benzoil-5 tiofene-2 acetico prodotto ottenuto e composizioni farmaceutiche che lo contengono

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7523501A FR2319340A1 (fr) 1975-07-28 1975-07-28 Nouveau sel de l'acide a-methyl benzoyl-5 thiophene-2 acetique, procede de preparation et application a titre de medicament

Publications (2)

Publication Number Publication Date
FR2319340A1 true FR2319340A1 (fr) 1977-02-25
FR2319340B1 FR2319340B1 (nl) 1978-11-10

Family

ID=9158436

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7523501A Granted FR2319340A1 (fr) 1975-07-28 1975-07-28 Nouveau sel de l'acide a-methyl benzoyl-5 thiophene-2 acetique, procede de preparation et application a titre de medicament

Country Status (13)

Country Link
US (1) US4318918A (nl)
JP (1) JPS5217462A (nl)
BE (1) BE844557A (nl)
CA (1) CA1068286A (nl)
CH (1) CH601285A5 (nl)
DE (1) DE2633891C2 (nl)
DK (1) DK145420C (nl)
FR (1) FR2319340A1 (nl)
GB (1) GB1488778A (nl)
IE (1) IE43929B1 (nl)
IT (1) IT7949862A0 (nl)
LU (1) LU75469A1 (nl)
NL (1) NL186005C (nl)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0449722A1 (fr) * 1990-03-27 1991-10-02 Roussel-Uclaf Nouveaux complexes de l'acide tiaprofénique ou de ses esters insolubles ou partiellement solubles avec les cyclodextrines ou leurs dérivés

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4810703A (en) * 1984-10-19 1989-03-07 A. H. Robins Company, Incorporated 1-((aminoalkyl and aminoalkylamino)carbonyl and thiocarbonyl)-alpha, alpha-diarylpyrrolidine, piperidine and homopiperidineacetamides and acetonitriles
GR880100839A (el) * 1988-12-15 1994-03-31 Ciba Geigy Αλας τρομε?αμίνης του 1-με?ύλ-Β-ΟΞΟ-Α-(φαινυλοκαρβομουλό)-2-πυρρολοπροπιονιτριλίου.
ES2058024B1 (es) * 1992-11-10 1995-05-01 Menarini Lab Nuevo derivado arilpropionico, procedimiento de fabricacion del mismo y su utilizacion como analgesico.
ES2124196B1 (es) * 1997-06-04 1999-12-01 Menarini Lab Procedimiento para la fabricacion de una forma farmaceutica semisolida conteniendo dexketoprofeno trometamol y su utilizacion en el tratamiento topico de la inflamacion.

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR4841M (nl) * 1964-05-07 1967-02-20
FR1516775A (fr) * 1966-07-13 1968-02-05 Rhone Poulenc Sa Nouveaux dérivés de l'acide benzoyl-4 phénylacétique et leur préparation
GB1195294A (en) * 1967-08-21 1970-06-17 Allen & Hanburys Ltd Improvements in or relating to Pharmaceutical Compositions
US3560525A (en) * 1967-10-13 1971-02-02 Parke Davis & Co 5-phenyl-2-furanacetic acids,5-phenyl-2-thiopheneacetic acids,and their derivatives
GB1271082A (en) * 1968-05-07 1972-04-19 Wyeth John & Brother Ltd Furan, pyrrole and thiophene derivatives
FR2068425B1 (nl) * 1969-11-12 1973-01-12 Roussel Uclaf
US3682964A (en) * 1970-08-31 1972-08-08 Roussel Uclaf Spiro benzocyclane acetic acid compounds

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
NEANT *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0449722A1 (fr) * 1990-03-27 1991-10-02 Roussel-Uclaf Nouveaux complexes de l'acide tiaprofénique ou de ses esters insolubles ou partiellement solubles avec les cyclodextrines ou leurs dérivés
FR2660309A1 (fr) * 1990-03-27 1991-10-04 Roussel Uclaf Nouveaux complexes de l'acide tiaprofenique ou de ses esters insolubles ou partiellement solubles avec les cyclodextrines ou leurs derives.

Also Published As

Publication number Publication date
GB1488778A (en) 1977-10-12
NL7608360A (nl) 1977-02-01
US4318918A (en) 1982-03-09
DK338576A (da) 1977-01-29
NL186005C (nl) 1990-09-03
DK145420B (da) 1982-11-15
JPS6119632B2 (nl) 1986-05-17
IE43929B1 (en) 1981-07-01
JPS5217462A (en) 1977-02-09
FR2319340B1 (nl) 1978-11-10
DK145420C (da) 1983-04-18
LU75469A1 (nl) 1977-04-06
IT7949862A0 (it) 1979-07-25
NL186005B (nl) 1990-04-02
CH601285A5 (nl) 1978-07-14
BE844557A (fr) 1977-01-27
IE43929L (en) 1977-01-28
DE2633891A1 (de) 1977-02-17
CA1068286A (en) 1979-12-18
DE2633891C2 (de) 1983-05-11

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Legal Events

Date Code Title Description
CC Supplementary protection certificate (spc) laid open to the public (law of 25 june 1990)

Free format text: 92C0035, 920305

CB Supplementary protection certificate (spc) granted (law of 25 june 1990)

Free format text: 92C0035, 750728

CP Supplementary protection certificate (spc) filed