FR2317917A1 - Oral and parenteral amino acid solutions - contg. essential and nonessential l-amino acids in specified proportions - Google Patents

Oral and parenteral amino acid solutions - contg. essential and nonessential l-amino acids in specified proportions

Info

Publication number
FR2317917A1
FR2317917A1 FR7620326A FR7620326A FR2317917A1 FR 2317917 A1 FR2317917 A1 FR 2317917A1 FR 7620326 A FR7620326 A FR 7620326A FR 7620326 A FR7620326 A FR 7620326A FR 2317917 A1 FR2317917 A1 FR 2317917A1
Authority
FR
France
Prior art keywords
nitrogen
amino acid
oral
parenteral
essential
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7620326A
Other languages
French (fr)
Other versions
FR2317917B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Dr Eduard Fresenius Chemisch Pharmazeutische Industrie KG
Original Assignee
Dr Eduard Fresenius Chemisch Pharmazeutische Industrie KG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dr Eduard Fresenius Chemisch Pharmazeutische Industrie KG filed Critical Dr Eduard Fresenius Chemisch Pharmazeutische Industrie KG
Publication of FR2317917A1 publication Critical patent/FR2317917A1/en
Application granted granted Critical
Publication of FR2317917B1 publication Critical patent/FR2317917B1/fr
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/01—Hydrolysed proteins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A61K31/405—Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Fodder In General (AREA)

Abstract

New L-amino acid mixts. for parenteral or oral use consist of essential and non-essential L-amino acids. Each 16 g of total amino acid nitrogen is made up of: 620-750 mg L-isoleucine nitrogen; 950-1220 mg L-leucine nitrogen; 1900-2250 mg L-lysine nitrogen; 480-600 mg L-methionine and/or L-cysteine and/or L-cystine nitrogen; 220-440 mg L-phenylalanine nitrogen; 700-800 mg L-threonine nitrogen; 210-450 mg L-tryptophan nitrogen; and 650-1000 mg L-valine nitrogen. The solns. are intended for oral or parenteral nutrition, e.g. after surgical operations or in diseases such as kidney disease. Using the amino acids in the proportions indicated above gives prods. with surprisingly high nutritive values. The new solns. have nutritive values of 148-155 after oral administration and 138-146 after parenteral administration. This compares with 137 for orally administered potato-egg protein mixts. and 130 for parenterally administered mixts. basedon potato-egg protein mixtures. In an example, an amino acid infusion soln. contains (per litre) 6.34 g L-isoleucine, 10.44 g L-leucine, 9.65 g L-lysine, 0.50 g L-cysteine HCl, 5.34 g L-methionine, 4.66 g L-phenylalanine, 6.16 g L-threonine, 1.60 g L-tryptophan, 7.48 g L-valine, 8.91 g L-arginine, 3.16 g L-histidine, 4.12 g glycine, 8.97 g L-alanine, 12.44 g L-serine, 6.36 g L-proline and 4.43 g L-tyrosine.
FR7620326A 1975-07-12 1976-07-02 Oral and parenteral amino acid solutions - contg. essential and nonessential l-amino acids in specified proportions Granted FR2317917A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19752531204 DE2531204C2 (en) 1975-07-12 1975-07-12 L-amino acid mixtures for parenteral or oral nutrition

Publications (2)

Publication Number Publication Date
FR2317917A1 true FR2317917A1 (en) 1977-02-11
FR2317917B1 FR2317917B1 (en) 1979-05-18

Family

ID=5951356

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7620326A Granted FR2317917A1 (en) 1975-07-12 1976-07-02 Oral and parenteral amino acid solutions - contg. essential and nonessential l-amino acids in specified proportions

Country Status (2)

Country Link
DE (1) DE2531204C2 (en)
FR (1) FR2317917A1 (en)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2935709A1 (en) * 1978-09-04 1980-03-13 Otsuka Pharma Co Ltd AMINO ACID SOLUTIONS AND THEIR USE
FR2711529A1 (en) * 1993-10-28 1995-05-05 Clintec Nutrition Cy Composition based on amino acids intended for the treatment of an infection or an aggression causing an inflammatory reaction, in animals and in humans.
EP1044017A1 (en) * 1998-01-05 2000-10-18 John Hopkins University School of Medicine Supplement for dialysis patients
WO2003013487A2 (en) * 2001-08-08 2003-02-20 Professional Dietetics S.R.L. Amino-acid-based compositions, suitable in therapy for the healing and/or mending of wounds and lesions, in particular for application in the ophthalmic field

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2946563C2 (en) * 1979-11-17 1987-04-30 B. Braun Melsungen Ag, 3508 Melsungen Amino acid solution for parenteral infusion
DE3821043A1 (en) * 1988-06-22 1989-12-28 Fresenius Ag DIALYZER AND SPUEL SOLUTION FOR INTRAPERITONEAL ADMINISTRATION
IT1289754B1 (en) * 1996-12-16 1998-10-16 Professional Dietetics Srl AMINO ACID BASED COMPOSITIONS

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2260189A1 (en) * 1971-12-09 1973-06-20 Hossein Ghadimi INJECTABLE AMINO ACID PREPARATIONS
FR2215212A1 (en) * 1973-01-18 1974-08-23 Seperic

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2530246A1 (en) * 1975-07-07 1977-01-13 Fresenius Chem Pharm Ind L-AMINO ACID MIXTURES FOR PARENTERAL OR ORAL USE

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2260189A1 (en) * 1971-12-09 1973-06-20 Hossein Ghadimi INJECTABLE AMINO ACID PREPARATIONS
FR2215212A1 (en) * 1973-01-18 1974-08-23 Seperic

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2935709A1 (en) * 1978-09-04 1980-03-13 Otsuka Pharma Co Ltd AMINO ACID SOLUTIONS AND THEIR USE
FR2711529A1 (en) * 1993-10-28 1995-05-05 Clintec Nutrition Cy Composition based on amino acids intended for the treatment of an infection or an aggression causing an inflammatory reaction, in animals and in humans.
EP0655244A1 (en) * 1993-10-28 1995-05-31 Clintec Nutrition Company Amino acid composition for the treatment of infections
EP1044017A1 (en) * 1998-01-05 2000-10-18 John Hopkins University School of Medicine Supplement for dialysis patients
EP1044017A4 (en) * 1998-01-05 2005-01-05 Univ Johns Hopkins Supplement for dialysis patients
WO2003013487A2 (en) * 2001-08-08 2003-02-20 Professional Dietetics S.R.L. Amino-acid-based compositions, suitable in therapy for the healing and/or mending of wounds and lesions, in particular for application in the ophthalmic field
WO2003013487A3 (en) * 2001-08-08 2003-05-30 Professional Dietetics Srl Amino-acid-based compositions, suitable in therapy for the healing and/or mending of wounds and lesions, in particular for application in the ophthalmic field

Also Published As

Publication number Publication date
FR2317917B1 (en) 1979-05-18
DE2531204C2 (en) 1987-01-22
DE2531204A1 (en) 1977-01-13

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