FR2315260A1 - Nouveaux composes araliphatiques dihalogenes, leur application en tant que medicaments et leur procede de preparation - Google Patents

Nouveaux composes araliphatiques dihalogenes, leur application en tant que medicaments et leur procede de preparation

Info

Publication number
FR2315260A1
FR2315260A1 FR7618098A FR7618098A FR2315260A1 FR 2315260 A1 FR2315260 A1 FR 2315260A1 FR 7618098 A FR7618098 A FR 7618098A FR 7618098 A FR7618098 A FR 7618098A FR 2315260 A1 FR2315260 A1 FR 2315260A1
Authority
FR
France
Prior art keywords
dihalogenous
preparation
new
application
medicinal products
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
FR7618098A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Patent GmbH
Original Assignee
Merck Patent GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent GmbH filed Critical Merck Patent GmbH
Publication of FR2315260A1 publication Critical patent/FR2315260A1/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/60—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by elimination of -OH groups, e.g. by dehydration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/132—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group
    • C07C29/136—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH
    • C07C29/147—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH of carboxylic acids or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/257—Ethers having an ether-oxygen atom bound to carbon atoms both belonging to six-membered aromatic rings
    • C07C43/295—Ethers having an ether-oxygen atom bound to carbon atoms both belonging to six-membered aromatic rings containing hydroxy or O-metal groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/52—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen
    • C07C57/58—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/52—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen
    • C07C57/58—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings
    • C07C57/60—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings having unsaturation outside the rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/64—Acyl halides
    • C07C57/76—Acyl halides containing halogen outside the carbonyl halide groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/42—Unsaturated compounds containing hydroxy or O-metal groups
    • C07C59/56—Unsaturated compounds containing hydroxy or O-metal groups containing halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
    • C07C59/66—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings
    • C07C59/68—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings the oxygen atom of the ether group being bound to a non-condensed six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F1/00—Compounds containing elements of Groups 1 or 11 of the Periodic System
    • C07F1/005—Compounds containing elements of Groups 1 or 11 of the Periodic System without C-Metal linkages
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids RP(=O)(OH)2; Thiophosphonic acids, i.e. RP(=X)(XH)2 (X = S, Se)
    • C07F9/40—Esters thereof
    • C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/4056—Esters of arylalkanephosphonic acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Obesity (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
FR7618098A 1975-06-28 1976-06-15 Nouveaux composes araliphatiques dihalogenes, leur application en tant que medicaments et leur procede de preparation Withdrawn FR2315260A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19752528958 DE2528958A1 (de) 1975-06-28 1975-06-28 Araliphatische dihalogenverbindungen und verfahren zu ihrer herstellung

Publications (1)

Publication Number Publication Date
FR2315260A1 true FR2315260A1 (fr) 1977-01-21

Family

ID=5950197

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7618098A Withdrawn FR2315260A1 (fr) 1975-06-28 1976-06-15 Nouveaux composes araliphatiques dihalogenes, leur application en tant que medicaments et leur procede de preparation

Country Status (19)

Country Link
US (1) US4057647A (fr)
JP (1) JPS525725A (fr)
AT (1) AT353254B (fr)
AU (1) AU498960B2 (fr)
BE (1) BE843486A (fr)
CA (1) CA1086770A (fr)
DE (1) DE2528958A1 (fr)
DK (1) DK287576A (fr)
ES (1) ES449219A1 (fr)
FR (1) FR2315260A1 (fr)
GB (1) GB1496627A (fr)
HU (1) HU175965B (fr)
IE (1) IE43248B1 (fr)
IL (1) IL49917A0 (fr)
IT (1) IT7948361A0 (fr)
LU (1) LU75245A1 (fr)
NL (1) NL7606972A (fr)
SE (1) SE7607241L (fr)
ZA (1) ZA763845B (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2626018A1 (de) * 1976-06-10 1977-12-22 Merck Patent Gmbh Alkinole und verfahren zu ihrer herstellung
US4263040A (en) * 1978-02-18 1981-04-21 Kumiai Chemical Industry Co., Ltd. Phenoxyphenoxy unsaturated derivatives and herbicidal composition
US4214004A (en) * 1978-12-04 1980-07-22 Fmc Corporation Insecticidal cyclopropanecarboxylates from substituted [1,1'-biphenyl]-3-ylmethyl compounds
US4468469A (en) * 1981-11-04 1984-08-28 Miles Laboratories, Inc. Substituted phenylacetic acids and salts as TBP blocking agents in iodothyronine immunoassays
IT1194209B (it) * 1983-04-21 1988-09-14 Medea Res Srl Composti fluorurati ad attivita' analgesica e antiinfiammatoria
JP6160610B2 (ja) * 2012-03-21 2017-07-12 日産化学工業株式会社 液晶配向剤、液晶配向膜及び液晶表示素子

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1270999A (en) * 1969-07-30 1972-04-19 Bdh Pharmaceuticals Ltd Propane-1,2-diol derivatives
BE790086A (fr) * 1971-10-15 1973-04-13 Thomae Gmbh Dr K Le 4-(4-biphenylyl)-1-butanol
DE2240440A1 (de) * 1972-08-17 1974-02-28 Thomae Gmbh Dr K Neue (4-biphenylyl)-alkohole und verfahren zu ihrer herstellung
US3969418A (en) * 1972-08-17 1976-07-13 Boehringer Ingelheim Gmbh (4-Biphenylyl)-butenols

Also Published As

Publication number Publication date
AU498960B2 (en) 1979-03-29
ATA468076A (de) 1979-04-15
AT353254B (de) 1979-11-12
LU75245A1 (fr) 1978-01-23
BE843486A (nl) 1976-12-28
DK287576A (da) 1976-12-29
AU1522076A (en) 1978-01-05
GB1496627A (en) 1977-12-30
ZA763845B (en) 1977-05-25
IL49917A0 (en) 1976-08-31
IE43248B1 (en) 1981-01-14
ES449219A1 (es) 1977-12-01
HU175965B (en) 1980-11-28
DE2528958A1 (de) 1977-01-13
IT7948361A0 (it) 1979-03-15
JPS525725A (en) 1977-01-17
CA1086770A (fr) 1980-09-30
US4057647A (en) 1977-11-08
NL7606972A (nl) 1976-12-30
IE43248L (en) 1976-12-28
SE7607241L (sv) 1976-12-29

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