FR2306983A1 - Nouveaux tetrazole-thiols - Google Patents

Nouveaux tetrazole-thiols

Info

Publication number
FR2306983A1
FR2306983A1 FR7620277A FR7620277A FR2306983A1 FR 2306983 A1 FR2306983 A1 FR 2306983A1 FR 7620277 A FR7620277 A FR 7620277A FR 7620277 A FR7620277 A FR 7620277A FR 2306983 A1 FR2306983 A1 FR 2306983A1
Authority
FR
France
Prior art keywords
thiols
new tetrazole
tetrazole
new
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7620277A
Other languages
English (en)
Other versions
FR2306983B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GlaxoSmithKline LLC
Original Assignee
SmithKline Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Corp filed Critical SmithKline Corp
Publication of FR2306983A1 publication Critical patent/FR2306983A1/fr
Application granted granted Critical
Publication of FR2306983B1 publication Critical patent/FR2306983B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D257/04—Five-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/18—7-Aminocephalosporanic or substituted 7-aminocephalosporanic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/36—Methylene radicals, substituted by sulfur atoms
FR7620277A 1974-12-27 1976-07-02 Nouveaux tetrazole-thiols Granted FR2306983A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/536,760 US4286089A (en) 1974-12-27 1974-12-27 7-Acyl-3-(substituted tetrazolyl thiomethyl)cephalosporins

Publications (2)

Publication Number Publication Date
FR2306983A1 true FR2306983A1 (fr) 1976-11-05
FR2306983B1 FR2306983B1 (fr) 1979-08-24

Family

ID=24139832

Family Applications (3)

Application Number Title Priority Date Filing Date
FR7539205A Granted FR2295751A1 (fr) 1974-12-27 1975-12-19 Nouveaux composes cephalosporaniques
FR7620277A Granted FR2306983A1 (fr) 1974-12-27 1976-07-02 Nouveaux tetrazole-thiols
FR7620274A Granted FR2306992A1 (fr) 1974-12-27 1976-07-02 Nouveaux composes cephalosporaniques 7-amines

Family Applications Before (1)

Application Number Title Priority Date Filing Date
FR7539205A Granted FR2295751A1 (fr) 1974-12-27 1975-12-19 Nouveaux composes cephalosporaniques

Family Applications After (1)

Application Number Title Priority Date Filing Date
FR7620274A Granted FR2306992A1 (fr) 1974-12-27 1976-07-02 Nouveaux composes cephalosporaniques 7-amines

Country Status (21)

Country Link
US (1) US4286089A (fr)
JP (1) JPS5188990A (fr)
AU (1) AU507050B2 (fr)
BE (1) BE837030A (fr)
CA (1) CA1108602A (fr)
CH (1) CH622523A5 (fr)
DD (1) DD122545A5 (fr)
DE (1) DE2558022A1 (fr)
DK (1) DK576075A (fr)
ES (1) ES443620A1 (fr)
FR (3) FR2295751A1 (fr)
GB (1) GB1537844A (fr)
HU (1) HU171833B (fr)
IE (1) IE42493B1 (fr)
IL (1) IL48691A0 (fr)
IT (1) IT1051940B (fr)
LU (1) LU74055A1 (fr)
NL (1) NL7515093A (fr)
SE (1) SE7514240L (fr)
YU (1) YU323775A (fr)
ZA (1) ZA756532B (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2526794A1 (fr) * 1982-05-13 1983-11-18 Shionogi & Co Procede de preparation d'acides mercaptotetrazolylalcanohydroxamiques, nouveaux produits ainsi obtenus et leur utilisation pour le traitement de l'alcoolisme et comme intermediaires

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4297489A (en) * 1974-09-03 1981-10-27 Bristol-Myers Company 7-α-Amino-substituted acylamino-3-(1-carboxymethyltetrazol-5-ylthiomethyl)-3-cephem-4-carboxylic acids
US4066762A (en) * 1976-07-12 1978-01-03 Smithkline Corporation Derivatives of 7-(2-substituted-2-hydroxyiminoacetamido)-3-(1-substituted tetrazol-5-ylthiomethyl-3-cephem-4-carboxylic acid
US4278670A (en) * 1976-07-12 1981-07-14 Smithkline Corporation 7-Alpha-oxyiminoacylcephalosporins
CA1115267A (fr) * 1976-08-30 1981-12-29 William J. Gottstein Acide 7-(2-alkyloxyimino-2-fur lacetamido)-3-(1- carboxyalkyl-tetrazolyl-5-thiomethyl)-3-cephem-4- carboxylique
EP0029998B1 (fr) * 1979-11-30 1985-03-06 Fujisawa Pharmaceutical Co., Ltd. Dérivés céphem, procédés pour leur préparation et compositions pharmaceutiques les contenant
US4420477A (en) * 1979-11-30 1983-12-13 Fujisawa Pharmaceutical Co., Ltd. Cephem compounds
US4346076A (en) * 1980-09-17 1982-08-24 Eli Lilly And Company Bis-tetrazoylmethyl substituted cephalosporin antibiotics
JPS59152385A (ja) * 1983-02-17 1984-08-31 Shionogi & Co Ltd ヒドロキサム酸系セフアロスポリン誘導体
PT87616B (pt) 1987-06-24 1992-09-30 Smithkline Beecham Corp Processo de preparacao de antagonistas do leucotrieno e de composicoes farmaceuticas
CH682878A5 (fr) * 1991-11-01 1993-12-15 Nestle Sa Procédé permettant d'éviter le brunissement d'un produit alimentaire.

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2249882A1 (fr) * 1973-10-31 1975-05-30 Fujisawa Pharmaceutical Co
FR2283686A1 (fr) * 1974-09-03 1976-04-02 Bristol Myers Co Nouveaux composes heterocycliques et compositions pharmaceutiques les contenant

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH557381A (de) * 1967-04-15 1974-12-31 Fujisawa Pharmaceutical Co Verfahren zur herstellung von (delta)3-cephemverbindungen.
US3819623A (en) * 1968-04-12 1974-06-25 Fujisawa Pharmaceutical Co 3,7-disubstituted cephalosporin compounds
NL173169C (nl) 1969-10-27 1983-12-16 Fujisawa Pharmaceutical Co Werkwijze voor het bereiden van een farmaceutisch preparaat met antibacteriele werking en werkwijze voor het bereiden van het daarvoor benodigde cephalosporinederivaat.
US3865819A (en) * 1972-05-03 1975-02-11 Smithkline Corp Substituted sulfonylacetamido cephalosporins
US3828037A (en) * 1972-07-20 1974-08-06 Smithkline Corp Trifluoromethylmercaptoacetamidocephalosporins
US4007173A (en) 1973-05-07 1977-02-08 Smithkline Corporation α-amino-α-(ureidophenyl)acetamidocephalosporins
US3884915A (en) * 1973-06-04 1975-05-20 Smithkline Corp 7-Alkylmercaptoacetamido cephalosporins
US3880848A (en) * 1973-06-18 1975-04-29 Smithkline Corp 7-Trifluorome thylsulfinylacetamido cephalosporins
GB1478055A (en) 1973-07-27 1977-06-29 Erba Carlo Spa Cephalosporin compounds
US3883520A (en) * 1973-08-17 1975-05-13 Smithkline Corp Substituted mercaptoacetamidocephalosporins
JPS5653557B2 (fr) * 1973-10-15 1981-12-19
JPS57873B2 (fr) 1973-12-25 1982-01-08
US4205166A (en) * 1974-02-20 1980-05-27 Fujisawa Pharmaceutical Co., Ltd. 7-Substituted-3-aminoalkyl-, acylaminoalkyl-, or hydroxyalkyl-substituted heterocyclic thiomethyl-3-cephem-4-carboxylic acid derivatives and preparation thereof
GB1509074A (en) 1974-04-05 1978-04-26 Yamanouchi Pharma Co Ltd Cephalosporin derivatives
GB1486272A (en) 1974-04-27 1977-09-21 Beecham Group Ltd Cephalosporins
GB1476981A (en) * 1974-06-05 1977-06-16 Bristol Myers Co Substituted penicillanic acids
US4172196A (en) * 1974-09-03 1979-10-23 Bristol-Myers Company Certain 7-α-substituted-α-hydroxyacetamido-3-(1-carboxymethyltetrazol-5-yl-thiomethyl)-3-cephem-4-carboxylic acids
US4182863A (en) * 1974-09-03 1980-01-08 Bristol-Myers Company 7-Amino-3-(1-carboxymethyltetrazol-5-ylthiomethyl)-3-cephem-4-carboxylic acid
DE2455071A1 (de) 1974-11-21 1976-05-26 Volkswagenwerk Ag Mit ladungsschichtung betriebene, fremdgezuendete brennkraftmaschine
JPS525787A (en) * 1975-06-27 1977-01-17 Bristol Myers Co Antiibacterial agent
US4198406A (en) * 1975-11-27 1980-04-15 Beecham Group Limited Carbamoyl heterocyclicthio cephalosporins and pharmaceutical compositions formulated therewith
US4220644A (en) * 1976-05-03 1980-09-02 Smithkline Corporation 7-Acylamino-3-(substituted tetrazolyl thiomethyl) cephalosporins

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2249882A1 (fr) * 1973-10-31 1975-05-30 Fujisawa Pharmaceutical Co
FR2283686A1 (fr) * 1974-09-03 1976-04-02 Bristol Myers Co Nouveaux composes heterocycliques et compositions pharmaceutiques les contenant

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2526794A1 (fr) * 1982-05-13 1983-11-18 Shionogi & Co Procede de preparation d'acides mercaptotetrazolylalcanohydroxamiques, nouveaux produits ainsi obtenus et leur utilisation pour le traitement de l'alcoolisme et comme intermediaires

Also Published As

Publication number Publication date
IE42493L (en) 1976-06-27
NL7515093A (nl) 1976-06-29
AU8764775A (en) 1977-06-23
CA1108602A (fr) 1981-09-08
FR2306992B1 (fr) 1978-09-01
LU74055A1 (fr) 1976-07-20
US4286089A (en) 1981-08-25
FR2306983B1 (fr) 1979-08-24
CH622523A5 (fr) 1981-04-15
FR2306992A1 (fr) 1976-11-05
IE42493B1 (en) 1980-08-27
GB1537844A (en) 1979-01-04
ZA756532B (en) 1976-09-29
BE837030A (fr) 1976-06-23
ES443620A1 (es) 1977-05-01
FR2295751B1 (fr) 1980-05-23
YU323775A (en) 1982-05-31
SE7514240L (sv) 1976-06-28
AU507050B2 (en) 1980-01-31
DE2558022A1 (de) 1976-07-08
DD122545A5 (fr) 1976-10-12
IL48691A0 (en) 1976-02-29
HU171833B (hu) 1978-03-28
IT1051940B (it) 1981-05-20
FR2295751A1 (fr) 1976-07-23
DK576075A (da) 1976-06-28
JPS5188990A (fr) 1976-08-04

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Legal Events

Date Code Title Description
ST Notification of lapse