FR22C1050I2 - 191P4D12 PROTEIN-BINDING ANTIBODY-DRUG CONJUGATES (ADCs) - Google Patents

191P4D12 PROTEIN-BINDING ANTIBODY-DRUG CONJUGATES (ADCs)

Info

Publication number
FR22C1050I2
FR22C1050I2 FR22C1050C FR22C1050C FR22C1050I2 FR 22C1050 I2 FR22C1050 I2 FR 22C1050I2 FR 22C1050 C FR22C1050 C FR 22C1050C FR 22C1050 C FR22C1050 C FR 22C1050C FR 22C1050 I2 FR22C1050 I2 FR 22C1050I2
Authority
FR
France
Prior art keywords
adcs
protein
binding antibody
drug conjugates
conjugates
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
FR22C1050C
Other languages
French (fr)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Agensys Inc
Seagen Inc
Original Assignee
Agensys Inc
Seagen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=45871300&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=FR22C1050(I2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Agensys Inc, Seagen Inc filed Critical Agensys Inc
Publication of FR22C1050I1 publication Critical patent/FR22C1050I1/en
Application granted granted Critical
Publication of FR22C1050I2 publication Critical patent/FR22C1050I2/en
Active legal-status Critical Current

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Classifications

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    • A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
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    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
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