FR2299021A1 - Composes anti-microbiens a base de carbamylguanidine - Google Patents

Composes anti-microbiens a base de carbamylguanidine

Info

Publication number
FR2299021A1
FR2299021A1 FR7602944A FR7602944A FR2299021A1 FR 2299021 A1 FR2299021 A1 FR 2299021A1 FR 7602944 A FR7602944 A FR 7602944A FR 7602944 A FR7602944 A FR 7602944A FR 2299021 A1 FR2299021 A1 FR 2299021A1
Authority
FR
France
Prior art keywords
carbamylguanidine
microbial compounds
microbial
compounds
carbamylguanidine anti
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7602944A
Other languages
English (en)
Other versions
FR2299021B1 (fr
Inventor
Julius Diamond
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cooper Laboratories Inc
Original Assignee
Cooper Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cooper Laboratories Inc filed Critical Cooper Laboratories Inc
Publication of FR2299021A1 publication Critical patent/FR2299021A1/fr
Application granted granted Critical
Publication of FR2299021B1 publication Critical patent/FR2299021B1/fr
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/17—Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/27—Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/04—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton
    • C07C279/14—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton being further substituted by carboxyl groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Organic Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
FR7602944A 1975-02-03 1976-02-03 Composes anti-microbiens a base de carbamylguanidine Granted FR2299021A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/546,549 US4022962A (en) 1975-02-03 1975-02-03 Carbamylguanidine antimicrobial compounds

Publications (2)

Publication Number Publication Date
FR2299021A1 true FR2299021A1 (fr) 1976-08-27
FR2299021B1 FR2299021B1 (fr) 1978-11-17

Family

ID=24180922

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7602944A Granted FR2299021A1 (fr) 1975-02-03 1976-02-03 Composes anti-microbiens a base de carbamylguanidine

Country Status (6)

Country Link
US (3) US4022962A (fr)
JP (1) JPS51101920A (fr)
CA (1) CA1070684A (fr)
DE (1) DE2602952A1 (fr)
FR (1) FR2299021A1 (fr)
GB (1) GB1531924A (fr)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4059624A (en) * 1970-11-27 1977-11-22 Colgate Palmolive Company Insolubilized salts of 1,6-di-p-(chlorophenyl biguanido) hexane
US4163022A (en) * 1975-02-03 1979-07-31 Cooper Laboratories, Inc. Carbamylguanidine antimicrobial compounds
US4203920A (en) * 1975-03-31 1980-05-20 William H. Rorer, Inc. Amidinoureas
US4204000A (en) * 1975-03-31 1980-05-20 William H. Rorer, Inc. Anti-ulcer amidinoureas
DE2648858A1 (de) * 1975-10-30 1977-05-18 Cooper Lab Antimikrobielle verbindungen auf der grundlage von bis-carbamylguanidinoazaalkanen
US4166827A (en) * 1975-10-30 1979-09-04 Cooper Laboratories, Inc. Bis-carbamylguanidinoazaalkane antimicrobial compounds
US4209624A (en) * 1976-10-26 1980-06-24 Cooper Laboratories, Inc. Process for preparing substituted bis(amidinoureas)
US4353842A (en) * 1978-09-14 1982-10-12 William H. Rorer, Inc. Amidinoureas
US4491660A (en) * 1980-01-10 1985-01-01 Abbott Laboratories Matrix polymers for binding endotoxins
DE3341018A1 (de) * 1983-11-12 1985-05-23 Bayer Ag, 5090 Leverkusen Verfahren zur herstellung von acylierten zuckern mit glycosidisch gebundener isothiocyanatgruppe
WO2005060951A2 (fr) * 2003-12-19 2005-07-07 Bionaut Pharmaceuticals, Inc. Argents anti-neoplasiques, therapies de combinaison et techniques associees
US20070105790A1 (en) * 2004-09-02 2007-05-10 Bionaut Pharmaceuticals, Inc. Pancreatic cancer treatment using Na+/K+ ATPase inhibitors
EP1796688B1 (fr) * 2004-09-02 2011-05-18 Bionaut Pharmaceuticals Inc Traitement du cancer du pancreas au moyen d'inhibiteurs d'aptase na+/k+
US20080027010A1 (en) * 2004-09-02 2008-01-31 Bionaut Pharmaceuticals, Inc. Treatment of refractory cancers using Na+/K+-ATPase inhibitors
US20060135468A1 (en) * 2004-09-02 2006-06-22 Bionaut Pharmaceuticals, Inc. Treatment of refractory cancers using NA+/K+ ATPase inhibitors
WO2006029018A2 (fr) * 2004-09-02 2006-03-16 Bionaut Pharmaceuticals, Inc. Traitement chimiotherapeutique combinatoire utilisant des inhibiteurs de na+/k+-atpase
WO2006044916A2 (fr) * 2004-10-18 2006-04-27 Bionaut Pharmaceuticals, Inc. Utilisation d'inhibiteurs de la na+/k+-atpase et leurs antagonistes

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2684924A (en) * 1951-02-05 1954-07-27 Ici Ltd Nu-chlorophenyldiguanidino compounds
BE612529A (fr) * 1961-01-13
US3564041A (en) * 1967-04-26 1971-02-16 Upjohn Co 1,2,3-trihydrocarbylguanidine-1-carboxylates
US3798269A (en) * 1968-08-05 1974-03-19 R Cutler Amidinoureas and amidinothioureas
US4022834A (en) * 1972-03-16 1977-05-10 A/S Farmaceutisk Industri Antibacterially active hexamethylene-bis-biguanides
US3903084A (en) * 1974-02-11 1975-09-02 Upjohn Co Carboximidoyl urea derivatives

Also Published As

Publication number Publication date
JPS51101920A (en) 1976-09-08
DE2602952A1 (de) 1976-12-23
AU1048676A (en) 1977-07-28
US4022962A (en) 1977-05-10
FR2299021B1 (fr) 1978-11-17
GB1531924A (en) 1978-11-15
US4115447A (en) 1978-09-19
CA1070684A (fr) 1980-01-29
US4115448A (en) 1978-09-19

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Legal Events

Date Code Title Description
ST Notification of lapse