FR2294702B1 - - Google Patents
Info
- Publication number
- FR2294702B1 FR2294702B1 FR7537775A FR7537775A FR2294702B1 FR 2294702 B1 FR2294702 B1 FR 2294702B1 FR 7537775 A FR7537775 A FR 7537775A FR 7537775 A FR7537775 A FR 7537775A FR 2294702 B1 FR2294702 B1 FR 2294702B1
- Authority
- FR
- France
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/84—Nitriles
- C07D213/85—Nitriles in position 3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US05/533,385 US4000282A (en) | 1974-12-16 | 1974-12-16 | 2-(3-tert. butyl or isopropylamino-2-hydroxypropoxy)-3-cyanopyridines |
| US05/713,558 US4096151A (en) | 1974-12-16 | 1976-08-11 | Certain 3-cyanopyridine intermediates |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2294702A1 FR2294702A1 (fr) | 1976-07-16 |
| FR2294702B1 true FR2294702B1 (US08066781-20111129-C00013.png) | 1979-09-28 |
Family
ID=27064163
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7537775A Granted FR2294702A1 (fr) | 1974-12-16 | 1975-12-10 | Nouvelles 3-cyano pyridines utiles comme medicaments |
Country Status (11)
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4060601A (en) * | 1976-06-15 | 1977-11-29 | Merck & Co., Inc. | Certain lower-alkyl amino-2'-hydroxy-propoxy pyridines |
| US4053605A (en) * | 1976-06-15 | 1977-10-11 | Merck & Co., Inc. | Esterified-2(3-lower-alkyl-amino-propoxy)-3-cyano-pyridines and derivatives |
| US4091104A (en) * | 1976-06-15 | 1978-05-23 | Merck & Co., Inc. | Substituted (3-loweralkylamino-2-R1 O-propoxy)pyridines, their preparation and use |
| US4144343A (en) * | 1978-01-04 | 1979-03-13 | Merck & Co., Inc. | Heterocycle substituted (3-loweralkylamino-2-R1 O-propoxy)pyridines |
| JPS54106476A (en) * | 1978-01-04 | 1979-08-21 | Merck & Co Inc | Multiisubstituted 22*33lower alkylaminoo22 r100propoxy*pyridine |
| US4279913A (en) * | 1978-01-04 | 1981-07-21 | Merck & Co., Inc. | Polysubstituted-2-(3-loweralkylamino-2-R1 O-propoxy)pyridines |
| US4294966A (en) * | 1978-07-28 | 1981-10-13 | Ciba-Geigy Corporation | Process for inverting the configuration in optically active compounds |
| US4393212A (en) * | 1979-01-29 | 1983-07-12 | Merck & Co., Inc. | Certain nicotinic acid esters and corresponding nicotinonitriles |
| US4294969A (en) * | 1979-01-29 | 1981-10-13 | Merck & Co., Inc. | Process for producing 2-bromo-3,5-disubstituted pyridines |
| US4234590A (en) * | 1979-02-05 | 1980-11-18 | Merck & Co., Inc. | Thiosubstituted pyridines |
| US4259327A (en) * | 1979-04-02 | 1981-03-31 | Merck & Co., Inc. | Substituted aminoalkoxypyridines, compositions and use thereof |
| US4329351A (en) * | 1979-10-01 | 1982-05-11 | Merck & Co., Inc. | 2-Substituted propoxy-3-cyano-5-RO-pyridines and intermediates |
| DE2943774A1 (de) * | 1979-10-26 | 1981-05-14 | 1000 Berlin Schering Ag Berlin Und Bergkamen | Substituierte pyridine, verfahren zu ihrer herstellung und ihre verwendung |
| US4254263A (en) * | 1979-11-02 | 1981-03-03 | Merck & Co., Inc. | Process for purifying a cyanopyridine compound |
| US4656168A (en) * | 1980-12-23 | 1987-04-07 | Merck & Co., Inc. | (3-aralkylamino-2-or-propoxy)heterocyclic compounds in method of effecting bronchodilation |
| US4442094A (en) * | 1980-12-23 | 1984-04-10 | Merck & Co., Inc. | (3-Aralkylamino-2-or-propoxy)heterocyclic compounds |
| US4331679A (en) * | 1980-12-23 | 1982-05-25 | Merck Sharp & Dohme (I.A.) Corp. | (3-Aralkylamino-2-or-propoxy) heterocyclic compounds |
| US4349673A (en) * | 1980-12-23 | 1982-09-14 | Merck & Co., Inc. | Benzoxazines |
| US4436740A (en) * | 1982-07-26 | 1984-03-13 | Merck & Co., Inc. | 3-Cycloalkylamino-2-OR-propoxycyanopyridines |
| US4550117A (en) * | 1982-07-26 | 1985-10-29 | Merck & Co., Inc. | 3-Cycloalkylamino-2-OR-propoxycyanopyridines, derivatives thereof, having anti-hypertensive activity |
| ES523901A0 (es) * | 1983-07-06 | 1985-04-01 | Fabr Prod Quimicos Y Farmaceut | Un procedimiento para la preparacion de derivados de 3-sulfonamidopiridinas 2 -sustituidas. |
| CA2330611A1 (en) | 1998-05-22 | 1999-12-02 | The Board Of Trustees Of The Leland Stanford Junior University | Bifunctional molecules and therapies based thereon |
| DE60234057D1 (de) | 2001-07-25 | 2009-11-26 | Raptor Pharmaceutical Inc | Zusammensetzungen und verfahren zur modulation des transports durch die blut-hirn-schranke |
| EP1889198B1 (en) | 2005-04-28 | 2014-11-26 | Proteus Digital Health, Inc. | Pharma-informatics system |
| WO2008036682A2 (en) | 2006-09-18 | 2008-03-27 | Raptor Pharmaceutical Inc. | Treatment of liver disorders by administration of receptor-associated protein (rap)-conjugates |
| DK3395372T3 (da) | 2009-02-20 | 2022-04-19 | Enhanx Biopharm Inc | System til afgivelse af glutathion-baseret medikament |
| EP2427178B1 (en) | 2009-05-06 | 2023-01-04 | Laboratory Skin Care, Inc. | Dermal delivery compositions comprising active agent-calcium phosphate particle complexes and methods of using the same |
| US20120077778A1 (en) | 2010-09-29 | 2012-03-29 | Andrea Bourdelais | Ladder-Frame Polyether Conjugates |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3459782A (en) * | 1963-08-26 | 1969-08-05 | Boehringer Sohn Ingelheim | 1-substituted phenoxy-2-hydroxy-3-isopropylamino-propanes |
| DE1919342A1 (de) | 1969-04-16 | 1970-12-03 | Boehringer Sohn Ingelheim | Herzwirksame Kombinationspraeparate |
| AR206801A1 (es) * | 1973-02-20 | 1976-08-23 | Ciba Geigy Ag | Procedimiento para la elaboracion de derivados del 1-pirid loxi-2-hidroxi-3-amino-propano |
| JPS5839832B2 (ja) * | 1974-02-20 | 1983-09-01 | チバ ガイギ− アクチエンゲゼルシヤフト | 新規ピラジン化合物の製法 |
| US4053605A (en) * | 1976-06-15 | 1977-10-11 | Merck & Co., Inc. | Esterified-2(3-lower-alkyl-amino-propoxy)-3-cyano-pyridines and derivatives |
| US4060601A (en) * | 1976-06-15 | 1977-11-29 | Merck & Co., Inc. | Certain lower-alkyl amino-2'-hydroxy-propoxy pyridines |
-
1974
- 1974-12-16 US US05/533,385 patent/US4000282A/en not_active Expired - Lifetime
-
1975
- 1975-12-02 SE SE7513571A patent/SE7513571L/xx unknown
- 1975-12-04 NL NL7514164A patent/NL7514164A/xx not_active Application Discontinuation
- 1975-12-08 CA CA241,258A patent/CA1064499A/en not_active Expired
- 1975-12-10 AU AU87436/75A patent/AU502129B2/en not_active Expired
- 1975-12-10 GB GB50629/75A patent/GB1496579A/en not_active Expired
- 1975-12-10 FR FR7537775A patent/FR2294702A1/fr active Granted
- 1975-12-10 GB GB17841/77A patent/GB1496580A/en not_active Expired
- 1975-12-12 LU LU74000A patent/LU74000A1/xx unknown
- 1975-12-12 DE DE19752559755 patent/DE2559755A1/de not_active Withdrawn
- 1975-12-12 DE DE2556110A patent/DE2556110C3/de not_active Expired
- 1975-12-15 BE BE162731A patent/BE836627A/xx unknown
- 1975-12-16 JP JP50149211A patent/JPS5186473A/ja active Pending
-
1976
- 1976-08-11 US US05/713,558 patent/US4096151A/en not_active Expired - Lifetime
-
1977
- 1977-09-02 US US05/830,246 patent/US4139535A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| JPS5186473A (US08066781-20111129-C00013.png) | 1976-07-29 |
| SE7513571L (sv) | 1976-06-17 |
| NL7514164A (nl) | 1976-06-18 |
| US4000282A (en) | 1976-12-28 |
| DE2556110C3 (de) | 1979-02-22 |
| AU8743675A (en) | 1977-06-16 |
| DE2556110A1 (de) | 1976-06-24 |
| CA1064499A (en) | 1979-10-16 |
| US4096151A (en) | 1978-06-20 |
| DE2559755A1 (de) | 1977-11-03 |
| GB1496580A (en) | 1977-12-30 |
| GB1496579A (en) | 1977-12-30 |
| BE836627A (fr) | 1976-06-15 |
| US4139535A (en) | 1979-02-13 |
| LU74000A1 (US08066781-20111129-C00013.png) | 1976-11-11 |
| AU502129B2 (en) | 1979-07-12 |
| DE2556110B2 (de) | 1978-06-15 |
| FR2294702A1 (fr) | 1976-07-16 |
Similar Documents
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |