FR2285886A2 - Procede de synthese de tetrahydro 1,4-oxazines 2,4-disubstituees - Google Patents
Procede de synthese de tetrahydro 1,4-oxazines 2,4-disubstitueesInfo
- Publication number
- FR2285886A2 FR2285886A2 FR7432772A FR7432772A FR2285886A2 FR 2285886 A2 FR2285886 A2 FR 2285886A2 FR 7432772 A FR7432772 A FR 7432772A FR 7432772 A FR7432772 A FR 7432772A FR 2285886 A2 FR2285886 A2 FR 2285886A2
- Authority
- FR
- France
- Prior art keywords
- active
- oxazines
- nervous system
- central nervous
- analgesics
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 229940035676 analgesics Drugs 0.000 title abstract 2
- 239000000730 antalgic agent Substances 0.000 title abstract 2
- 210000003169 central nervous system Anatomy 0.000 title abstract 2
- 239000003795 chemical substances by application Substances 0.000 title abstract 2
- BQJCRHHNABKAKU-KBQPJGBKSA-N morphine Chemical compound O([C@H]1[C@H](C=C[C@H]23)O)C4=C5[C@@]12CCN(C)[C@@H]3CC5=CC=C4O BQJCRHHNABKAKU-KBQPJGBKSA-N 0.000 abstract 2
- 125000001494 2-propynyl group Chemical group [H]C#CC([H])([H])* 0.000 abstract 1
- 208000007271 Substance Withdrawal Syndrome Diseases 0.000 abstract 1
- 229940125681 anticonvulsant agent Drugs 0.000 abstract 1
- 239000001961 anticonvulsive agent Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 125000001449 isopropyl group Chemical group [H]C([H])([H])C([H])(*)C([H])([H])[H] 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 229960005181 morphine Drugs 0.000 abstract 1
- 150000004893 oxazines Chemical class 0.000 abstract 1
- 239000003091 serenic agent Substances 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7432772A FR2285886A2 (fr) | 1974-09-27 | 1974-09-27 | Procede de synthese de tetrahydro 1,4-oxazines 2,4-disubstituees |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7432772A FR2285886A2 (fr) | 1974-09-27 | 1974-09-27 | Procede de synthese de tetrahydro 1,4-oxazines 2,4-disubstituees |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2285886A2 true FR2285886A2 (fr) | 1976-04-23 |
| FR2285886B2 FR2285886B2 (Direct) | 1979-03-30 |
Family
ID=9143538
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7432772A Granted FR2285886A2 (fr) | 1974-09-27 | 1974-09-27 | Procede de synthese de tetrahydro 1,4-oxazines 2,4-disubstituees |
Country Status (1)
| Country | Link |
|---|---|
| FR (1) | FR2285886A2 (Direct) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2553411A1 (fr) * | 1983-10-14 | 1985-04-19 | Lafon Labor | Derives de 2-halogenophenyl-morpholine, procede de preparation et utilisation en therapeutique |
| EP0435387A1 (en) * | 1989-12-29 | 1991-07-03 | Shell Internationale Researchmaatschappij B.V. | Piperidine derivatives |
| EP2221304A1 (en) | 2005-07-22 | 2010-08-25 | Mitsubishi Tanabe Pharma Corporation | Method for synthesizing intermediate compound for synthesizing a pharmaceutical agent |
| US8906908B2 (en) | 2010-05-21 | 2014-12-09 | Research Triangle Institute | Hydroxybupropion analogues for treating drug dependence |
| US9617229B2 (en) | 2010-05-21 | 2017-04-11 | Research Triangle Institute | Phenylmorpholines and analogues thereof |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR1564792A (Direct) * | 1968-03-04 | 1969-04-25 |
-
1974
- 1974-09-27 FR FR7432772A patent/FR2285886A2/fr active Granted
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR1564792A (Direct) * | 1968-03-04 | 1969-04-25 |
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2553411A1 (fr) * | 1983-10-14 | 1985-04-19 | Lafon Labor | Derives de 2-halogenophenyl-morpholine, procede de preparation et utilisation en therapeutique |
| EP0435387A1 (en) * | 1989-12-29 | 1991-07-03 | Shell Internationale Researchmaatschappij B.V. | Piperidine derivatives |
| EP2221304A1 (en) | 2005-07-22 | 2010-08-25 | Mitsubishi Tanabe Pharma Corporation | Method for synthesizing intermediate compound for synthesizing a pharmaceutical agent |
| EP2221305A1 (en) | 2005-07-22 | 2010-08-25 | Mitsubishi Tanabe Pharma Corporation | Method for synthesizing intermediate compound for synthesizing a pharmaceutical agent |
| US7994315B2 (en) | 2005-07-22 | 2011-08-09 | Mitsubishi Tanabe Pharma Corporation | Intermediate compound for synthesizing pharmaceutical agent and production method thereof |
| US8906908B2 (en) | 2010-05-21 | 2014-12-09 | Research Triangle Institute | Hydroxybupropion analogues for treating drug dependence |
| US9527823B2 (en) | 2010-05-21 | 2016-12-27 | Research Triangle Institute | Hydroxybupropion analogues for treating drug dependence |
| US9617229B2 (en) | 2010-05-21 | 2017-04-11 | Research Triangle Institute | Phenylmorpholines and analogues thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| FR2285886B2 (Direct) | 1979-03-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| CD | Change of name or company name |