FR2274230A1 - Iron protoporphyrin derivs. separation from globin - by selective precipitation in the presence of organic solvents - Google Patents

Iron protoporphyrin derivs. separation from globin - by selective precipitation in the presence of organic solvents

Info

Publication number
FR2274230A1
FR2274230A1 FR7518352A FR7518352A FR2274230A1 FR 2274230 A1 FR2274230 A1 FR 2274230A1 FR 7518352 A FR7518352 A FR 7518352A FR 7518352 A FR7518352 A FR 7518352A FR 2274230 A1 FR2274230 A1 FR 2274230A1
Authority
FR
France
Prior art keywords
globin
liq
pref
derivs
iron
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7518352A
Other languages
French (fr)
Other versions
FR2274230B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of FR2274230A1 publication Critical patent/FR2274230A1/en
Application granted granted Critical
Publication of FR2274230B1 publication Critical patent/FR2274230B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/22—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains four or more hetero rings
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23J—PROTEIN COMPOSITIONS FOR FOODSTUFFS; WORKING-UP PROTEINS FOR FOODSTUFFS; PHOSPHATIDE COMPOSITIONS FOR FOODSTUFFS
    • A23J1/00—Obtaining protein compositions for foodstuffs; Bulk opening of eggs and separation of yolks from whites
    • A23J1/06—Obtaining protein compositions for foodstuffs; Bulk opening of eggs and separation of yolks from whites from blood
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/795—Porphyrin- or corrin-ring-containing peptides
    • C07K14/805—Haemoglobins; Myoglobins

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Food Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Extraction Or Liquid Replacement (AREA)
  • Fodder In General (AREA)

Abstract

In a process for sepg. iron protoporphyrin and its derivs. or decompsn. and cleavage prods. (the so-called iron components) from globin in a liq. contg. blood substances, the liq. is cooled, pref. to 0 to -20 degrees C, and adjusted to pH 4.5 (pref. 2.5-4.5), an org. solvent having dehydrating props. (e.g. ethanol or its mixts. with glycol or glycerol) is added in an amt. of is not 40 vol% (pref. is not 70 vol%) (based on the total amt. of liq.) while maintainin cooling, and the precipitated iron components are sepd. off from the liq., pref. by addn. of salts such as KCl or sodium citrate, the globin being subsequently precipitated from the liq. Although the sepn. of iron components and globin is readily performable on a laboratory scale, the methods used are not suitable for large scale operation. The new process is simple and economical and can be used on large scale, permitting the sepn. of globin in amts. suitable for use in feedstuffs or foods.
FR7518352A 1974-06-14 1975-06-12 Iron protoporphyrin derivs. separation from globin - by selective precipitation in the presence of organic solvents Granted FR2274230A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE7407882-5A SE389596B (en) 1974-06-14 1974-06-14 SUGGESTED TO SEPARATE GLOBIN IRON COMPOUNDS FROM A VETICAL CONTAINING BLOOD SUBSTANCES

Publications (2)

Publication Number Publication Date
FR2274230A1 true FR2274230A1 (en) 1976-01-09
FR2274230B1 FR2274230B1 (en) 1981-03-27

Family

ID=20321445

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7518352A Granted FR2274230A1 (en) 1974-06-14 1975-06-12 Iron protoporphyrin derivs. separation from globin - by selective precipitation in the presence of organic solvents

Country Status (18)

Country Link
AR (1) AR209770A1 (en)
AT (1) AT346672B (en)
AU (1) AU502954B2 (en)
BR (1) BR7503722A (en)
CA (1) CA1055489A (en)
DE (1) DE2526596C2 (en)
DK (1) DK150173B (en)
ES (1) ES438483A1 (en)
FI (1) FI59195C (en)
FR (1) FR2274230A1 (en)
HU (1) HU174189B (en)
IE (1) IE49166B1 (en)
PL (1) PL94776B1 (en)
RO (1) RO63791A (en)
SE (1) SE389596B (en)
SU (1) SU910135A3 (en)
YU (1) YU147475A (en)
ZA (1) ZA753806B (en)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0013055A1 (en) * 1978-12-22 1980-07-09 Unilever N.V. Process of preparing blood cell protein and heme from hemoglobin
FR2535173A1 (en) * 1982-11-03 1984-05-04 Protein Sa Products obtained from the blood of abattoir animals and method for obtaining them.
FR2548671A1 (en) * 1983-07-07 1985-01-11 Merieux Inst PROCESS FOR THE PREPARATION OF A GLOBIN FROM HEMOGLOBIN AND A GLOBIN OBTAINED BY THIS PROCESS
EP0236971A2 (en) * 1986-03-12 1987-09-16 BASF Aktiengesellschaft Process for the isolation and purification of haemin
WO1998028302A1 (en) * 1996-12-20 1998-07-02 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Method of obtaining haemin from slaughter blood

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE440596B (en) * 1980-04-03 1985-08-12 Paul Goran Sigvard Lindroos PROCEDURE FOR PREPARING A HOME CONCENTRATE FROM A MIXTURE OF HOME AND BLOOD SUBSTANCE RECOVERY BY DIVISION OF HEMOGLOBIN
JPS59128337A (en) * 1983-01-11 1984-07-24 Riyoushiyoku Kenkyukai Recovery of blood globin and haem
EP0397890B1 (en) * 1988-11-18 1994-09-07 Tosoh Corporation Process for purifying blood plasma

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE178902C (en) * 1905-10-16
SE348942B (en) * 1970-06-02 1972-09-18 Statens Bakteriologiska Labor

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0013055A1 (en) * 1978-12-22 1980-07-09 Unilever N.V. Process of preparing blood cell protein and heme from hemoglobin
FR2535173A1 (en) * 1982-11-03 1984-05-04 Protein Sa Products obtained from the blood of abattoir animals and method for obtaining them.
FR2548671A1 (en) * 1983-07-07 1985-01-11 Merieux Inst PROCESS FOR THE PREPARATION OF A GLOBIN FROM HEMOGLOBIN AND A GLOBIN OBTAINED BY THIS PROCESS
EP0134729A1 (en) * 1983-07-07 1985-03-20 Institut Merieux Process for the preparation of globin from hemoglobin, and globin obtained in this process
EP0236971A2 (en) * 1986-03-12 1987-09-16 BASF Aktiengesellschaft Process for the isolation and purification of haemin
EP0236971A3 (en) * 1986-03-12 1989-01-18 Basf Aktiengesellschaft Process for the isolation and purification of haemin
WO1998028302A1 (en) * 1996-12-20 1998-07-02 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Method of obtaining haemin from slaughter blood

Also Published As

Publication number Publication date
RO63791A (en) 1978-12-15
AU8166875A (en) 1976-12-02
FI751643A (en) 1975-12-15
FR2274230B1 (en) 1981-03-27
SE389596B (en) 1976-11-15
BR7503722A (en) 1976-06-29
FI59195C (en) 1981-07-10
PL94776B1 (en) 1977-08-31
AT346672B (en) 1978-11-27
SE7407882L (en) 1975-12-15
DE2526596A1 (en) 1976-01-02
FI59195B (en) 1981-03-31
ZA753806B (en) 1977-01-26
ATA456575A (en) 1978-03-15
IE49166B1 (en) 1985-08-21
ES438483A1 (en) 1977-02-01
DK266675A (en) 1975-12-15
HU174189B (en) 1979-11-28
AU502954B2 (en) 1979-08-16
YU147475A (en) 1982-05-31
DE2526596C2 (en) 1984-11-29
DK150173B (en) 1986-12-29
SU910135A3 (en) 1982-02-28
CA1055489A (en) 1979-05-29
AR209770A1 (en) 1977-05-31

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