FR2270863A1 - - Google Patents

Info

Publication number
FR2270863A1
FR2270863A1 FR7514655A FR7514655A FR2270863A1 FR 2270863 A1 FR2270863 A1 FR 2270863A1 FR 7514655 A FR7514655 A FR 7514655A FR 7514655 A FR7514655 A FR 7514655A FR 2270863 A1 FR2270863 A1 FR 2270863A1
Authority
FR
France
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7514655A
Other versions
FR2270863B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Publication of FR2270863A1 publication Critical patent/FR2270863A1/fr
Application granted granted Critical
Publication of FR2270863B1 publication Critical patent/FR2270863B1/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/63—One oxygen atom
    • C07D213/64—One oxygen atom attached in position 2 or 6
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/63—One oxygen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81—Amides; Imides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32—One oxygen, sulfur or nitrogen atom
    • C07D239/34—One oxygen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D241/18—Oxygen or sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
FR7514655A 1974-05-14 1975-05-12 Expired FR2270863B1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CH658274A CH591448A5 (fr) 1974-05-14 1974-05-14
CH156177A CH592625A5 (fr) 1974-05-14 1974-05-14
CH661874A CH594626A5 (fr) 1974-05-14 1974-05-14

Publications (2)

Publication Number Publication Date
FR2270863A1 true FR2270863A1 (fr) 1975-12-12
FR2270863B1 FR2270863B1 (fr) 1979-05-18

Family

ID=27173079

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7514655A Expired FR2270863B1 (fr) 1974-05-14 1975-05-12

Country Status (12)

Country Link
US (1) US4027027A (fr)
JP (1) JPS50154213A (fr)
AT (1) AT345288B (fr)
AU (1) AU8104575A (fr)
BE (1) BE828989A (fr)
CA (1) CA1067077A (fr)
CH (3) CH592625A5 (fr)
DE (1) DE2520910A1 (fr)
FR (1) FR2270863B1 (fr)
GB (1) GB1493006A (fr)
NL (1) NL7504864A (fr)
SE (1) SE7504375L (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2383930A1 (fr) * 1977-03-17 1978-10-13 Basf Ag Ethers aminoalcoyliques de pyridinyle, leurs procedes d'obtention et preparations pharmaceutiques les contenant
EP1074544A1 (fr) * 1999-08-02 2001-02-07 Kaneka Corporation Procédé pour la production de dérivés du 3-(3-pyridyl)-1-propanol

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4193995A (en) * 1972-05-05 1980-03-18 Merck Sharp & Dohme (I.A.) Corp. 2-(3-Substituted amino-2-hydroxypropoxy)-3-substituted pyrazine compounds and compositions
US4195090A (en) * 1973-02-20 1980-03-25 Ciba-Geigy Corporation 2-(3-Amino-2-hydroxy-propoxy)pyridine derivatives and pharmaceutical compositions therewith
US4853383A (en) * 1975-03-03 1989-08-01 Merck & Co., Inc. β-blocking substituted imidazoles
US4440774A (en) * 1975-03-03 1984-04-03 Merck & Co., Inc. 3-Amino-2-hydroxypropoxyaryl imidazole derivatives
US4263323A (en) * 1976-10-07 1981-04-21 Aktiebolaget Hassle β-Receptor blocking compounds and treatment of cardiovascular disorders therewith
FI782133A (fi) * 1977-07-08 1979-01-09 Ciba Geigy Ag Piperidino-propanoler och foerfarande foer deras framstaellning
US4235919A (en) 1977-07-21 1980-11-25 Sandoz Ltd. 1-(Indol-4-yloxy)-3-(2-substituted amino)-2-propanols and pharmaceutical use thereof
US4263325A (en) * 1977-10-05 1981-04-21 Aktiebolaget Hassle β-Receptor blocking compounds and treatment of cardiovascular disorders therewith
DK267779A (da) * 1978-06-27 1979-12-28 Merck & Co Inc Fr&mgangsmaade til fremstilling af n-aralkylamino-propoxycyanopyridiner
US4210653A (en) * 1978-06-27 1980-07-01 Merck & Co., Inc. Pyridyloxypropanolamines
US4208416A (en) * 1978-06-27 1980-06-17 Merck & Co., Inc. N-Aralkyl containing cyanopyridines
JPS55124742A (en) * 1979-03-20 1980-09-26 Kyowa Hakko Kogyo Co Ltd Novel aminoalcohol derivative
IT1165040B (it) * 1979-04-23 1987-04-22 Isf Spa Alcossialchilidenidrazinopiridazione e procedimento per la loro preparazione
DE3048487A1 (de) * 1980-12-22 1982-07-29 Cassella Ag, 6000 Frankfurt Basisch substituierte pyridazine, ihre herstellung und ihre verwendung
US4599333A (en) * 1982-06-14 1986-07-08 Teikoku Hormone Mfg. Co., Ltd. Hydrazinopyridazine compound, process for production thereof, and use thereof as medicament
US4598149A (en) * 1984-03-02 1986-07-01 Merck & Co., Inc. 3-amino-2-hydroxypropyl of pyrimidin-4-one useful as antihypertensive, cardioprotective, antiarrythmic, and antianginal agents
US4920134A (en) * 1987-08-07 1990-04-24 Takeda Chemical Industries, Ltd. 2-O-pyrimidinyl glycerol derivatives
US5221674A (en) * 1989-06-19 1993-06-22 Teikoku Hormone Mfg. Co., Ltd. Pyridazinone derivatives
NZ234087A (en) * 1989-06-19 1991-08-27 Teikoku Hormone Mfg Co Ltd 2-(3-aryloxy(2-hydroxy-propylamino))-2-methylpropyl- aminophenyl pyridazine derivatives
US5998404A (en) * 1994-10-24 1999-12-07 Eli Lilly And Company Heterocyclic compounds and their use

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
LU65414A1 (fr) * 1972-05-24 1973-12-04

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2383930A1 (fr) * 1977-03-17 1978-10-13 Basf Ag Ethers aminoalcoyliques de pyridinyle, leurs procedes d'obtention et preparations pharmaceutiques les contenant
EP1074544A1 (fr) * 1999-08-02 2001-02-07 Kaneka Corporation Procédé pour la production de dérivés du 3-(3-pyridyl)-1-propanol
US6388086B1 (en) 1999-08-02 2002-05-14 Kaneka Corporation Process for production of 3-(3-pyridyl)-1-propanol derivatives

Also Published As

Publication number Publication date
CH592625A5 (fr) 1977-10-31
NL7504864A (nl) 1975-11-18
JPS50154213A (fr) 1975-12-12
DE2520910A1 (de) 1975-12-04
FR2270863B1 (fr) 1979-05-18
ATA364675A (de) 1978-01-15
CA1067077A (fr) 1979-11-27
BE828989A (fr) 1975-11-13
SE7504375L (sv) 1975-11-17
AT345288B (de) 1978-09-11
AU8104575A (en) 1976-11-18
CH594626A5 (fr) 1978-01-13
US4027027A (en) 1977-05-31
CH591448A5 (fr) 1977-09-15
GB1493006A (en) 1977-11-23

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Legal Events

Date Code Title Description
ST Notification of lapse