FR2267781A1 - 3-Pyridyl amino ergoline derivs - for treatment of galactorrhoea, breast cancer, oedema, hypertension, parkinsons disease etc. - Google Patents
3-Pyridyl amino ergoline derivs - for treatment of galactorrhoea, breast cancer, oedema, hypertension, parkinsons disease etc.Info
- Publication number
- FR2267781A1 FR2267781A1 FR7511771A FR7511771A FR2267781A1 FR 2267781 A1 FR2267781 A1 FR 2267781A1 FR 7511771 A FR7511771 A FR 7511771A FR 7511771 A FR7511771 A FR 7511771A FR 2267781 A1 FR2267781 A1 FR 2267781A1
- Authority
- FR
- France
- Prior art keywords
- treatment
- oedema
- hypertension
- breast cancer
- galactorrhoea
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000011282 treatment Methods 0.000 title abstract 4
- -1 3-Pyridyl amino Chemical group 0.000 title abstract 2
- 206010006187 Breast cancer Diseases 0.000 title abstract 2
- 208000026310 Breast neoplasm Diseases 0.000 title abstract 2
- 206010017600 Galactorrhoea Diseases 0.000 title abstract 2
- 206010020772 Hypertension Diseases 0.000 title abstract 2
- 206010030113 Oedema Diseases 0.000 title abstract 2
- 208000018737 Parkinson disease Diseases 0.000 title abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000003349 3-pyridyl group Chemical group N1=C([H])C([*])=C([H])C([H])=C1[H] 0.000 abstract 1
- AWFDCTXCTHGORH-HGHGUNKESA-N 6-[4-[(6ar,9r,10ar)-5-bromo-7-methyl-6,6a,8,9,10,10a-hexahydro-4h-indolo[4,3-fg]quinoline-9-carbonyl]piperazin-1-yl]-1-methylpyridin-2-one Chemical compound O=C([C@H]1CN([C@H]2[C@@H](C=3C=CC=C4NC(Br)=C(C=34)C2)C1)C)N(CC1)CCN1C1=CC=CC(=O)N1C AWFDCTXCTHGORH-HGHGUNKESA-N 0.000 abstract 1
- 208000001287 Galactorrhea Diseases 0.000 abstract 1
- 206010061218 Inflammation Diseases 0.000 abstract 1
- 208000019695 Migraine disease Diseases 0.000 abstract 1
- 206010036618 Premenstrual syndrome Diseases 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000004414 alkyl thio group Chemical group 0.000 abstract 1
- 230000033228 biological regulation Effects 0.000 abstract 1
- 230000001684 chronic effect Effects 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 230000004054 inflammatory process Effects 0.000 abstract 1
- 230000006651 lactation Effects 0.000 abstract 1
- 206010027599 migraine Diseases 0.000 abstract 1
- 238000011321 prophylaxis Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
- C07D457/10—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hetero atoms directly attached in position 8
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
- C07D457/10—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hetero atoms directly attached in position 8
- C07D457/12—Nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH523274 | 1974-04-16 | ||
| CH189375 | 1975-02-14 | ||
| CH189475 | 1975-02-14 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2267781A1 true FR2267781A1 (en) | 1975-11-14 |
| FR2267781B1 FR2267781B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1978-08-04 |
Family
ID=27173325
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7511771A Granted FR2267781A1 (en) | 1974-04-16 | 1975-04-16 | 3-Pyridyl amino ergoline derivs - for treatment of galactorrhoea, breast cancer, oedema, hypertension, parkinsons disease etc. |
Country Status (12)
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0001062A1 (de) * | 1977-09-02 | 1979-03-21 | Sandoz Ag | Ergolin-Derivate, Verfahren zu ihrer Herstellung, diese enthaltende pharmazeutische Zusammensetzungen und ihre Anwendung bei therapeutischen Behandlungen |
| DE3227122A1 (de) * | 1982-07-20 | 1984-01-26 | Dr. Rentschler Arzneimittel Gmbh & Co, 7958 Laupheim | Stabile loesungen von mutterkornalkaloiden |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1573621A (en) * | 1976-01-02 | 1980-08-28 | Sandoz Ltd | Acylated 6-methyl-8a-amino-ergoline i compounds |
-
1975
- 1975-04-07 FI FI751031A patent/FI751031A7/fi not_active Application Discontinuation
- 1975-04-07 DK DK147775A patent/DK147775A/da not_active IP Right Cessation
- 1975-04-07 DE DE19752515100 patent/DE2515100A1/de active Pending
- 1975-04-08 SE SE7504036A patent/SE7504036L/xx unknown
- 1975-04-11 NL NL7504330A patent/NL7504330A/xx unknown
- 1975-04-14 ES ES436569A patent/ES436569A1/es not_active Expired
- 1975-04-14 AU AU80114/75A patent/AU8011475A/en not_active Expired
- 1975-04-14 IL IL47085A patent/IL47085A0/xx unknown
- 1975-04-15 JP JP50044910A patent/JPS50137998A/ja active Pending
- 1975-04-15 DD DD185464A patent/DD121638A5/xx unknown
- 1975-04-16 FR FR7511771A patent/FR2267781A1/fr active Granted
- 1975-10-08 NO NO751210*[A patent/NO751210L/no unknown
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0001062A1 (de) * | 1977-09-02 | 1979-03-21 | Sandoz Ag | Ergolin-Derivate, Verfahren zu ihrer Herstellung, diese enthaltende pharmazeutische Zusammensetzungen und ihre Anwendung bei therapeutischen Behandlungen |
| DE3227122A1 (de) * | 1982-07-20 | 1984-01-26 | Dr. Rentschler Arzneimittel Gmbh & Co, 7958 Laupheim | Stabile loesungen von mutterkornalkaloiden |
Also Published As
| Publication number | Publication date |
|---|---|
| DE2515100A1 (de) | 1975-11-06 |
| FR2267781B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1978-08-04 |
| DD121638A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1976-08-12 |
| NO751210L (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1975-10-17 |
| AU8011475A (en) | 1976-10-21 |
| SE7504036L (sv) | 1975-10-17 |
| FI751031A7 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1975-10-17 |
| ES436569A1 (es) | 1977-04-01 |
| JPS50137998A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1975-11-01 |
| DK147775A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1975-10-17 |
| IL47085A0 (en) | 1975-08-31 |
| NL7504330A (nl) | 1975-10-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |