FR2260342A1 - Piperazine phenoxybutazone salts - as antiinflammatory agents having good gastric tolerance and low toxicity - Google Patents
Piperazine phenoxybutazone salts - as antiinflammatory agents having good gastric tolerance and low toxicityInfo
- Publication number
- FR2260342A1 FR2260342A1 FR7501495A FR7501495A FR2260342A1 FR 2260342 A1 FR2260342 A1 FR 2260342A1 FR 7501495 A FR7501495 A FR 7501495A FR 7501495 A FR7501495 A FR 7501495A FR 2260342 A1 FR2260342 A1 FR 2260342A1
- Authority
- FR
- France
- Prior art keywords
- piperazine
- salts
- phenoxybutazone
- antiinflammatory agents
- low toxicity
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- GLUUGHFHXGJENI-UHFFFAOYSA-N Piperazine Chemical compound C1CNCCN1 GLUUGHFHXGJENI-UHFFFAOYSA-N 0.000 title abstract 4
- 229940121363 anti-inflammatory agent Drugs 0.000 title abstract 2
- 239000002260 anti-inflammatory agent Substances 0.000 title abstract 2
- 230000002496 gastric effect Effects 0.000 title abstract 2
- 231100000053 low toxicity Toxicity 0.000 title 1
- 150000003839 salts Chemical class 0.000 title 1
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 abstract 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 2
- 239000002904 solvent Substances 0.000 abstract 2
- 241000699670 Mus sp. Species 0.000 abstract 1
- 150000004885 piperazines Chemical class 0.000 abstract 1
- CYMJPJKHCSDSRG-UHFFFAOYSA-N pyrazolidine-3,4-dione Chemical class O=C1CNNC1=O CYMJPJKHCSDSRG-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
- C07D295/027—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D231/28—Two oxygen or sulfur atoms
- C07D231/30—Two oxygen or sulfur atoms attached in positions 3 and 5
- C07D231/32—Oxygen atoms
- C07D231/34—Oxygen atoms with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached in position 4
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES423129A ES423129A1 (es) | 1974-02-12 | 1974-02-12 | Procedimiento para la obtencion de nuevos farmacos antiin- flamatorios. |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2260342A1 true FR2260342A1 (en) | 1975-09-05 |
| FR2260342B1 FR2260342B1 (ref) | 1979-08-10 |
Family
ID=8465944
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7501495A Granted FR2260342A1 (en) | 1974-02-12 | 1975-01-17 | Piperazine phenoxybutazone salts - as antiinflammatory agents having good gastric tolerance and low toxicity |
Country Status (4)
| Country | Link |
|---|---|
| BE (1) | BE825044A (ref) |
| DE (1) | DE2456312C3 (ref) |
| ES (1) | ES423129A1 (ref) |
| FR (1) | FR2260342A1 (ref) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU203538B (en) * | 1988-03-10 | 1991-08-28 | Richter Gedeon Vegyeszet | Process for producing 1,2-diphenyl-3,5-dioxy-4-butyl-pirazolidin-sodium-monohydrate |
-
1974
- 1974-02-12 ES ES423129A patent/ES423129A1/es not_active Expired
- 1974-11-28 DE DE2456312A patent/DE2456312C3/de not_active Expired
-
1975
- 1975-01-17 FR FR7501495A patent/FR2260342A1/fr active Granted
- 1975-01-31 BE BE152932A patent/BE825044A/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| DE2456312B2 (de) | 1978-06-08 |
| DE2456312C3 (de) | 1979-02-01 |
| DE2456312A1 (de) | 1975-08-21 |
| BE825044A (fr) | 1975-05-15 |
| FR2260342B1 (ref) | 1979-08-10 |
| ES423129A1 (es) | 1976-04-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |