FR2259590A1 - 2-(3-Pyrazolyl)benzimidazoles - with vasodilator, analgesic, antiinflammatory and hypotensive activity - Google Patents

2-(3-Pyrazolyl)benzimidazoles - with vasodilator, analgesic, antiinflammatory and hypotensive activity

Info

Publication number
FR2259590A1
FR2259590A1 FR7403681A FR7403681A FR2259590A1 FR 2259590 A1 FR2259590 A1 FR 2259590A1 FR 7403681 A FR7403681 A FR 7403681A FR 7403681 A FR7403681 A FR 7403681A FR 2259590 A1 FR2259590 A1 FR 2259590A1
Authority
FR
France
Prior art keywords
benzimidazoles
vasodilator
antiinflammatory
analgesic
pyrazolyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7403681A
Other languages
French (fr)
Other versions
FR2259590B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Synthelabo SA
Original Assignee
Delalande SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Delalande SA filed Critical Delalande SA
Priority to FR7403681A priority Critical patent/FR2259590A1/en
Publication of FR2259590A1 publication Critical patent/FR2259590A1/en
Application granted granted Critical
Publication of FR2259590B1 publication Critical patent/FR2259590B1/fr
Granted legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond

Abstract

2-(3-Pyrazolyl) benzimidazoles of formula (I) (where Ar is phenyl (opt. substd. by F or >=1 OMe) beta-pyridyl, alpha-furyl or alpha-thienyl) have vasodilator analgesic, antiinflammatory and hypotensive activity, oral dose is 50-500 mg 1-6 times daily or 10-100 mg, 1-5 times daily parenterally, or 1-3 suppositories daily each contg. 50-300 mg of (I).
FR7403681A 1974-02-04 1974-02-04 2-(3-Pyrazolyl)benzimidazoles - with vasodilator, analgesic, antiinflammatory and hypotensive activity Granted FR2259590A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR7403681A FR2259590A1 (en) 1974-02-04 1974-02-04 2-(3-Pyrazolyl)benzimidazoles - with vasodilator, analgesic, antiinflammatory and hypotensive activity

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7403681A FR2259590A1 (en) 1974-02-04 1974-02-04 2-(3-Pyrazolyl)benzimidazoles - with vasodilator, analgesic, antiinflammatory and hypotensive activity

Publications (2)

Publication Number Publication Date
FR2259590A1 true FR2259590A1 (en) 1975-08-29
FR2259590B1 FR2259590B1 (en) 1977-09-09

Family

ID=9134447

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7403681A Granted FR2259590A1 (en) 1974-02-04 1974-02-04 2-(3-Pyrazolyl)benzimidazoles - with vasodilator, analgesic, antiinflammatory and hypotensive activity

Country Status (1)

Country Link
FR (1) FR2259590A1 (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4107489A1 (en) * 1991-03-08 1992-09-10 Beiersdorf Ag Cosmetic for make=up and hair treating compsn. - contains new 2-(3'-aryl-acryloxy)-benzimidazole cpd. as UV absorber
CN102660253A (en) * 2012-03-07 2012-09-12 泰山医学院 Pyrazoline derivative Ni<2+> fluorescence probe and application thereof

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4107489A1 (en) * 1991-03-08 1992-09-10 Beiersdorf Ag Cosmetic for make=up and hair treating compsn. - contains new 2-(3'-aryl-acryloxy)-benzimidazole cpd. as UV absorber
CN102660253A (en) * 2012-03-07 2012-09-12 泰山医学院 Pyrazoline derivative Ni<2+> fluorescence probe and application thereof
CN102660253B (en) * 2012-03-07 2014-05-21 泰山医学院 Pyrazoline derivative Ni<2+> fluorescence probe and application thereof

Also Published As

Publication number Publication date
FR2259590B1 (en) 1977-09-09

Similar Documents

Publication Publication Date Title
CA1273019C (en) Enkephalinase inhibitors
LU88579I2 (en) ATOVAQUONE and its pharmaceutically acceptable salts (WELLVONE R)
ES485098A1 (en) Dibenzothiepin derivatives and a process for producing the same
FR2259590A1 (en) 2-(3-Pyrazolyl)benzimidazoles - with vasodilator, analgesic, antiinflammatory and hypotensive activity
ES428005A1 (en) 3,4-Dihydro-2H-naphthalene-1-one-5-oxypropyl-piperazine compounds
GB1293507A (en) Derivatives of 3-carbamoyl-2-oxazolidinone, and their process of preparation
ES418857A1 (en) Sulfur-containing ring compounds
GB1081944A (en) Benzdiaz[1,4]epine derivatives
ES456689A1 (en) Bis-trimethylsilyl cefamandole and process therefor
FR2168136A1 (en) 2-aminobenzoyl hydrazones - with antiinflammatory, analgesic and antipyretic activity
FR2276035A1 (en) Substd-indane-5-carboxylic acids - with antiinflammatory, analgesic and antipyretic activity
ES400453A1 (en) N-acyl-(piperazinoalkyl)-pyrazoles
ES8400384A1 (en) Carbacyclines, process for their preparation and their use as medicines.
ES434045A1 (en) Alkylmercaptomethylquinoxaline-1,4-dioxides and oxidized derivatives thereof
ES442427A1 (en) Pyrazolidinones and a process for their preparation
ES402365A1 (en) 2-pyridazinylisoindolin-1-one derivatives
ES449895A1 (en) 4-Acylaminophenylacetamidines and a method for their preparation
FR2363629A1 (en) ACTIVATORS FOR PERCOMPOSES
MY100599A (en) Derivatives of cycloalkanols and cycloalkenols
FR2244501A1 (en) 5-Chloro-3-formyl-2-methylindoles - with diuretic analgesic and antiinflammatory activity
ES8200666A1 (en) Novel N-acylcarnosine aluminum salts, for treatment of digestive ulcers
ES447365A1 (en) Phenylalkanol nitriles
FR2239471A1 (en) Corynanthine hydrazides - as therapeutic agents
ES448550A1 (en) 6-Aminomethylated 3-oxygenated cholest-5-enes
FR2313042A1 (en) Analgesic 4-(2-alkoxyanilino) quinolines - some having antiinflammatory activity

Legal Events

Date Code Title Description
ST Notification of lapse