FR2250764A1 - - Google Patents

Info

Publication number
FR2250764A1
FR2250764A1 FR7437148A FR7437148A FR2250764A1 FR 2250764 A1 FR2250764 A1 FR 2250764A1 FR 7437148 A FR7437148 A FR 7437148A FR 7437148 A FR7437148 A FR 7437148A FR 2250764 A1 FR2250764 A1 FR 2250764A1
Authority
FR
France
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7437148A
Other languages
French (fr)
Other versions
FR2250764B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of FR2250764A1 publication Critical patent/FR2250764A1/fr
Application granted granted Critical
Publication of FR2250764B1 publication Critical patent/FR2250764B1/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
FR7437148A 1973-11-12 1974-11-08 Expired FR2250764B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US415186A US3887545A (en) 1973-11-12 1973-11-12 Synthesis of 1{60 -hydroxylated cholesterol derivatives

Publications (2)

Publication Number Publication Date
FR2250764A1 true FR2250764A1 (en) 1975-06-06
FR2250764B1 FR2250764B1 (en) 1979-08-03

Family

ID=23644712

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7437148A Expired FR2250764B1 (en) 1973-11-12 1974-11-08

Country Status (9)

Country Link
US (1) US3887545A (en)
JP (1) JPS5438098B2 (en)
AT (1) AT342793B (en)
BE (1) BE821983A (en)
CH (1) CH599247A5 (en)
DE (1) DE2453648C3 (en)
FR (1) FR2250764B1 (en)
GB (1) GB1443680A (en)
NL (1) NL7414675A (en)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3993675A (en) * 1975-02-24 1976-11-23 Hoffmann-La Roche Inc. Process for the preparation of 1α,25-dihydroxycholecalciferol
US4264512A (en) * 1975-09-29 1981-04-28 The Regents Of The University Of California 3-Deoxy-1α-hydroxy- and 3-deoxy-1α,25-dihydroxycholecalciferol and processes for the preparation thereof
JPS603045B2 (en) * 1976-04-19 1985-01-25 中外製薬株式会社 Method for producing 1α-hydroxyvitamin D soft capsules
US4098801A (en) * 1977-01-26 1978-07-04 Hoffmann-La Roche Inc. Synthesis of 1α-hydroxylated derivatives of cholesterol
US4260549A (en) * 1979-05-21 1981-04-07 Wisconsin Alumni Research Foundation Process for preparing 1α-hydroxylated compounds
LU80545A1 (en) * 1978-11-17 1980-06-05 Hoffmann La Roche METHOD FOR PRODUCING 1A, 3S-DIHYDROXY-> 5-STEROIDS
US4217279A (en) * 1978-12-18 1980-08-12 Kaiser Emil T Synthesis of steroids
US5952317A (en) * 1995-09-21 1999-09-14 Wisconsin Alumni Research Foundation Calcitriol derivatives and their uses
US5976784A (en) * 1996-09-20 1999-11-02 Wisconsin Alumni Research Foundation Calcitriol derivatives and their uses
EP0946584B1 (en) 1996-12-20 2003-04-23 Novo Nordisk A/S Meiosis regulating compounds
KR20020028876A (en) * 1999-04-30 2002-04-17 추후제출 Steroid derivatives
JP2005508281A (en) * 2001-02-08 2005-03-31 ザ ユニバーシティー オブ シカゴ Steroid derivatives
US20070197484A1 (en) * 2001-05-03 2007-08-23 Ching Song Method of treating disorder related to high cholesterol concentration
US7078396B2 (en) * 2001-05-03 2006-07-18 Arch Development Corporation Method of treating disorder related to high cholesterol concentration
WO2003086303A2 (en) * 2002-04-12 2003-10-23 The University Of Chicago Farnesoid x-activated receptor agonists
CA2495882A1 (en) * 2002-08-29 2004-03-11 The Regents Of The University Of California Agents and methods for enhancing bone formation
WO2005020928A2 (en) * 2003-08-29 2005-03-10 The Regents Of The University Of California Agents and methods for enhancing bone formation by oxysterols in combination with bone morphogenic proteins
US20070032464A1 (en) * 2004-10-08 2007-02-08 Shutsung Liao Methods of treating cancers
CN101163882B (en) * 2005-04-23 2011-08-10 艾克塞蒂克马克有限公司 Axial piston motor and manufacturing method
WO2007028101A2 (en) * 2005-09-02 2007-03-08 The Regents Of The University Of California Osteogenic and anti-adiogenic oxysterols
EP1993558B1 (en) * 2006-02-27 2014-07-30 The Regents of The University of California Oxysterol compounds and the hedgehog pathway
US20100048944A1 (en) * 2006-07-19 2010-02-25 Farhad Parhami Interactions of hedgehog and liver x receptor signaling pathways
CA2673513A1 (en) 2006-12-19 2008-07-10 The Regents Of University Of California Inhibition of ppar gamma expression by specific osteogenic oxysterols
AU2008331808B2 (en) * 2007-03-16 2014-08-21 The Regents Of The University Of California Oxysterols for activation of hedgehog signaling, osteoinduction, antiadipogenesis, and Wnt signaling
WO2008115469A2 (en) * 2007-03-16 2008-09-25 The Regents Of The University Of California Role of hedgehog signaling in atherosclerosis and cardiovascular disease
JP2013500986A (en) * 2009-07-29 2013-01-10 ザ・ユニバーシティ・オブ・シカゴ Liver X receptor agonist
KR20150013232A (en) 2012-05-07 2015-02-04 더 리전트 오브 더 유니버시티 오브 캘리포니아 Oxysterol analogue oxy133 induces osteogenesis and hedgehog signaling and inhibits adipogenesis
JP2016517888A (en) 2013-05-02 2016-06-20 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア Oxysterol bone targeting drug for osteoselective bone formation
CN114315947B (en) * 2021-11-17 2023-10-03 王涛 New method for synthesizing cholesterol and 25-hydroxycholesterol by using 22-sterol as raw material
CN116789726A (en) * 2022-01-28 2023-09-22 珂阑(上海)医药科技有限公司 Steroid compound, preparation method and application thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3080937A (en) * 1960-11-07 1963-03-12 Garbell Res Foundation Combined acoustic wall and exhaust gas deflector in operation of jet engines
US3741996A (en) * 1971-12-02 1973-06-26 Wisconsin Alumni Res Found 1{60 -hydroxycholecalciferol

Also Published As

Publication number Publication date
ATA899274A (en) 1977-08-15
BE821983A (en) 1975-05-09
JPS5077360A (en) 1975-06-24
JPS5438098B2 (en) 1979-11-19
FR2250764B1 (en) 1979-08-03
DE2453648C3 (en) 1981-08-06
DE2453648B2 (en) 1980-06-26
US3887545A (en) 1975-06-03
GB1443680A (en) 1976-07-21
DE2453648A1 (en) 1975-05-15
NL7414675A (en) 1975-05-14
CH599247A5 (en) 1978-05-31
AT342793B (en) 1978-04-25

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Legal Events

Date Code Title Description
ST Notification of lapse