FR2243688A1 - Beta-Aryloxy-or-arylthio-acrylic acid derivs. - prepd. e.g. by reacting (thio)phenols with propiolic acid derivs. - Google Patents

Beta-Aryloxy-or-arylthio-acrylic acid derivs. - prepd. e.g. by reacting (thio)phenols with propiolic acid derivs.

Info

Publication number
FR2243688A1
FR2243688A1 FR7431210A FR7431210A FR2243688A1 FR 2243688 A1 FR2243688 A1 FR 2243688A1 FR 7431210 A FR7431210 A FR 7431210A FR 7431210 A FR7431210 A FR 7431210A FR 2243688 A1 FR2243688 A1 FR 2243688A1
Authority
FR
France
Prior art keywords
alk
obtd
opt
formula
converted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
FR7431210A
Other languages
French (fr)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Publication of FR2243688A1 publication Critical patent/FR2243688A1/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C17/00—Preparation of halogenated hydrocarbons
    • C07C17/26—Preparation of halogenated hydrocarbons by reactions involving an increase in the number of carbon atoms in the skeleton
    • C07C17/263—Preparation of halogenated hydrocarbons by reactions involving an increase in the number of carbon atoms in the skeleton by condensation reactions
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C17/00—Preparation of halogenated hydrocarbons
    • C07C17/26—Preparation of halogenated hydrocarbons by reactions involving an increase in the number of carbon atoms in the skeleton
    • C07C17/263—Preparation of halogenated hydrocarbons by reactions involving an increase in the number of carbon atoms in the skeleton by condensation reactions
    • C07C17/2632—Preparation of halogenated hydrocarbons by reactions involving an increase in the number of carbon atoms in the skeleton by condensation reactions involving an organo-magnesium compound, e.g. Grignard synthesis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyridine Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Derivs. of formula R1-Ph-X-alk-Y (I) (where R1 is a mono- or bicyclic cycloaliphatic hydrocarbon residue, Ph is opt. substd. phenylene, X is O or S, alk is 1,2-alkenylene, and Y is an opt. functionally modified carboxyl group) (e.g. ethyl p- p-(1-cyclohexenyl)-phenoxy -crotonate) are new compounds which may be prepd. by reacting a cpd. of the formula R1-Ph-XH (II) with a cpd. alk'-Y (III) (where alk' is the 2-Z-1-alkenyl or 1-alkynyl residue corresponding to alk, and Z is an opt. reactively esterified OH group, a 2-hydroxy-1-alkenyl residue opt. being present in the form of the tautomeric 2-oxo-alkyl residue). Prods. of formula (I) obtd. may be converted into different compounds of formula (I). Isomer or racemate mixts. obtd. may be septd. into the individual isomers or racemates, and racemates obtd. may be septd. into the optical antipodes. Salts obtd. may be converted into the corresponding free cpds., or the free cpds. may be converted into their salts. (I) are useful as antiallergic agents (they inhibit histamine release and anaphylactic reactions) and hypolipaemic agents (they lower blood cholesterol and triglyceride levels in rats in standard tests).
FR7431210A 1973-09-18 1974-09-16 Beta-Aryloxy-or-arylthio-acrylic acid derivs. - prepd. e.g. by reacting (thio)phenols with propiolic acid derivs. Withdrawn FR2243688A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH1338873 1973-09-18

Publications (1)

Publication Number Publication Date
FR2243688A1 true FR2243688A1 (en) 1975-04-11

Family

ID=4391993

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7431210A Withdrawn FR2243688A1 (en) 1973-09-18 1974-09-16 Beta-Aryloxy-or-arylthio-acrylic acid derivs. - prepd. e.g. by reacting (thio)phenols with propiolic acid derivs.

Country Status (8)

Country Link
JP (1) JPS5053357A (en)
AU (1) AU7333774A (en)
BE (1) BE819986A (en)
DE (1) DE2443401A1 (en)
DK (1) DK422774A (en)
FR (1) FR2243688A1 (en)
NL (1) NL7412260A (en)
SE (1) SE7410724L (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2546319C2 (en) * 1975-10-16 1986-02-27 Dr. Karl Thomae Gmbh, 7950 Biberach Cyclohexylphenyl derivatives, processes for their preparation and agents containing them
MX9708552A (en) * 1995-05-09 1997-12-31 Basf Ag (het)aryloxy-, -thio-, aminocrotonates, methods of preparing them and their use as insecticides and fungicides.

Also Published As

Publication number Publication date
DE2443401A1 (en) 1975-03-20
AU7333774A (en) 1976-03-18
DK422774A (en) 1975-05-20
SE7410724L (en) 1975-03-19
JPS5053357A (en) 1975-05-12
BE819986A (en) 1975-03-17
NL7412260A (en) 1975-03-20

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Legal Events

Date Code Title Description
ST Notification of lapse