FR2236494A1 - N-(1,2,6,7,8,8a-hexahydro-benzo(c,d)-indole-1-yl)-guanidines - as salidiuretic agents - Google Patents
N-(1,2,6,7,8,8a-hexahydro-benzo(c,d)-indole-1-yl)-guanidines - as salidiuretic agentsInfo
- Publication number
- FR2236494A1 FR2236494A1 FR7424213A FR7424213A FR2236494A1 FR 2236494 A1 FR2236494 A1 FR 2236494A1 FR 7424213 A FR7424213 A FR 7424213A FR 7424213 A FR7424213 A FR 7424213A FR 2236494 A1 FR2236494 A1 FR 2236494A1
- Authority
- FR
- France
- Prior art keywords
- alkyl
- guanidines
- hexahydro
- indole
- benzo
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/80—[b, c]- or [b, d]-condensed
- C07D209/90—Benzo [c, d] indoles; Hydrogenated benzo [c, d] indoles
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Indole Compounds (AREA)
Abstract
Guanidines (I), their salts have the formula:-(where R1 is H or CHR4R4; R3 and R5 are H or alkyl; R2 is H, alkyl, 5 or 6C-cyclo-alkyl, 7-9C-phenylalkyl and wherein the benzene nucleus is opt. substd. by halogen. CF3, alkyl or alkoxy; R3 is H; primary or secondary-alkyl, 3-6C cycloalkyl, allyl, OH, NH2, dialkylamino, 7-9C-phenylalkyl linked to the N atom via C atom carrying at least one H and wherein the benzene nucleus is opt substd. by halogen, CF3 alkyl or alkoxy; provided that R1 R2 and R3 are not all N, & R2, is H when R3 is allyl, alkyl, cycloalkyl or opt. substd. phenylalkyl) and are useful as diuretic agents.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH1009973 | 1973-07-11 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| FR2236494A1 true FR2236494A1 (en) | 1975-02-07 |
Family
ID=4359331
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7424213A Withdrawn FR2236494A1 (en) | 1973-07-11 | 1974-07-11 | N-(1,2,6,7,8,8a-hexahydro-benzo(c,d)-indole-1-yl)-guanidines - as salidiuretic agents |
Country Status (15)
| Country | Link |
|---|---|
| JP (1) | JPS5037772A (en) |
| AU (1) | AU7107374A (en) |
| BE (1) | BE817503A (en) |
| CS (1) | CS170116B2 (en) |
| DD (1) | DD112757A5 (en) |
| DE (1) | DE2431356A1 (en) |
| DK (1) | DK354674A (en) |
| FI (1) | FI201874A (en) |
| FR (1) | FR2236494A1 (en) |
| HU (1) | HU168306B (en) |
| IL (1) | IL45223A0 (en) |
| NL (1) | NL7409118A (en) |
| NO (1) | NO742418L (en) |
| SE (1) | SE7408790L (en) |
| ZA (1) | ZA744451B (en) |
-
1974
- 1974-06-29 DE DE2431356A patent/DE2431356A1/en active Pending
- 1974-07-02 FI FI2018/74A patent/FI201874A/fi unknown
- 1974-07-02 DK DK354674A patent/DK354674A/da unknown
- 1974-07-03 NO NO742418A patent/NO742418L/no unknown
- 1974-07-03 SE SE7408790A patent/SE7408790L/en not_active Application Discontinuation
- 1974-07-05 NL NL7409118A patent/NL7409118A/en unknown
- 1974-07-09 DD DD179815A patent/DD112757A5/xx unknown
- 1974-07-09 CS CS4872A patent/CS170116B2/cs unknown
- 1974-07-09 HU HUSA2671A patent/HU168306B/hu unknown
- 1974-07-09 IL IL45223A patent/IL45223A0/en unknown
- 1974-07-10 AU AU71073/74A patent/AU7107374A/en not_active Expired
- 1974-07-10 JP JP49078383A patent/JPS5037772A/ja active Pending
- 1974-07-10 BE BE146435A patent/BE817503A/en unknown
- 1974-07-11 FR FR7424213A patent/FR2236494A1/en not_active Withdrawn
- 1974-07-11 ZA ZA00744451A patent/ZA744451B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IL45223A0 (en) | 1974-10-22 |
| SE7408790L (en) | 1975-01-13 |
| NO742418L (en) | 1975-02-10 |
| ZA744451B (en) | 1976-02-25 |
| DD112757A5 (en) | 1975-05-05 |
| DK354674A (en) | 1975-03-03 |
| HU168306B (en) | 1976-03-28 |
| BE817503A (en) | 1975-01-10 |
| FI201874A (en) | 1975-01-12 |
| DE2431356A1 (en) | 1975-01-30 |
| CS170116B2 (en) | 1976-08-27 |
| NL7409118A (en) | 1975-01-14 |
| JPS5037772A (en) | 1975-04-08 |
| AU7107374A (en) | 1976-01-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |