FR2233037A1 - Injectable antineuritic solutions - made and stored under acid conditions by adjusted to physilogical acidity just before administration - Google Patents

Injectable antineuritic solutions - made and stored under acid conditions by adjusted to physilogical acidity just before administration

Info

Publication number
FR2233037A1
FR2233037A1 FR7420803A FR7420803A FR2233037A1 FR 2233037 A1 FR2233037 A1 FR 2233037A1 FR 7420803 A FR7420803 A FR 7420803A FR 7420803 A FR7420803 A FR 7420803A FR 2233037 A1 FR2233037 A1 FR 2233037A1
Authority
FR
France
Prior art keywords
antineuritic
injectable
solns
soln
acidity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7420803A
Other languages
French (fr)
Other versions
FR2233037B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
INST LLORENTE SA
Original Assignee
INST LLORENTE SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by INST LLORENTE SA filed Critical INST LLORENTE SA
Publication of FR2233037A1 publication Critical patent/FR2233037A1/en
Application granted granted Critical
Publication of FR2233037B1 publication Critical patent/FR2233037B1/fr
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner

Landscapes

  • Health & Medical Sciences (AREA)
  • Dermatology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Injectable solns of antineuritic mixtures, contain vitamins, coenzymes and associations of these. The vitamins and coenzymes are prepd. at pH 2.5-5 and are stabilised by lyophilisation or other means to preserve their chemical structure and activity and, this matl. is converted into an injectable soln. by means of a solvent which is kept separate but supplied in the same package as the active matl, the solvent being a buffered, pyrogenic sterile soln. contg. physiological ions which gives the final soln. og pH of 6-6.4: the soln. being administered within an hour of its prepn. Conventional antineuritic solns are at pH 2.5-5 in order to preserve the activity of the vitamins etc. Such solns cause local irritation because of their acidity. The novel solns. maintain the activity but are free from side effects.
FR7420803A 1973-06-15 1974-06-14 Injectable antineuritic solutions - made and stored under acid conditions by adjusted to physilogical acidity just before administration Granted FR2233037A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES415972A ES415972A1 (en) 1973-06-15 1973-06-15 Procedure for the preparation of injectable solutions of complexes of antineuritic indication, of vitamins, coferments, and their associations. (Machine-translation by Google Translate, not legally binding)

Publications (2)

Publication Number Publication Date
FR2233037A1 true FR2233037A1 (en) 1975-01-10
FR2233037B1 FR2233037B1 (en) 1978-07-28

Family

ID=8464419

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7420803A Granted FR2233037A1 (en) 1973-06-15 1974-06-14 Injectable antineuritic solutions - made and stored under acid conditions by adjusted to physilogical acidity just before administration

Country Status (4)

Country Link
JP (1) JPS5035322A (en)
DE (1) DE2428226A1 (en)
ES (1) ES415972A1 (en)
FR (1) FR2233037A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2598081B1 (en) * 1986-04-30 1990-02-02 Chauvin Blache Lab PROCESS FOR THE PREPARATION OF AN AQUEOUS PHARMACEUTICAL SOLUTION OF AN ACTIVE INGREDIENT CONSTITUTED BY AN ORGANIC ACID

Also Published As

Publication number Publication date
ES415972A1 (en) 1974-04-01
FR2233037B1 (en) 1978-07-28
DE2428226A1 (en) 1975-03-27
JPS5035322A (en) 1975-04-04

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Legal Events

Date Code Title Description
ST Notification of lapse