FR2231370A2 - 3-Carbamoyloxy-5-methyl-isothiazoles - as antibacterial and antifungal agents for treating man and animals - Google Patents

3-Carbamoyloxy-5-methyl-isothiazoles - as antibacterial and antifungal agents for treating man and animals

Info

Publication number
FR2231370A2
FR2231370A2 FR7319424A FR7319424A FR2231370A2 FR 2231370 A2 FR2231370 A2 FR 2231370A2 FR 7319424 A FR7319424 A FR 7319424A FR 7319424 A FR7319424 A FR 7319424A FR 2231370 A2 FR2231370 A2 FR 2231370A2
Authority
FR
France
Prior art keywords
carbamoyloxy
antibacterial
animals
antifungal agents
isothiazoles
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7319424A
Other languages
French (fr)
Other versions
FR2231370B2 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Roussel Uclaf SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf SA filed Critical Roussel Uclaf SA
Priority to FR7319424A priority Critical patent/FR2231370A2/en
Publication of FR2231370A2 publication Critical patent/FR2231370A2/en
Application granted granted Critical
Publication of FR2231370B2 publication Critical patent/FR2231370B2/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D275/00—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings
    • C07D275/02—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings not condensed with other rings
    • C07D275/03—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/005—Antimicrobial preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q15/00—Anti-perspirants or body deodorants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00—Preparations for care of the hair
    • A61Q5/02—Preparations for cleaning the hair

Abstract

Pharmaceutical compsns contain as active component a 3-carbamoyloxy-k-methylisothiazole of formula: (where R1 is H, 1-6C alkyl; R2 is 1-6c alkyl). Cpds (I) are antibacterial and antifungal agents suitable for pharmaceutical use in addn. to the industrial uses described in the parent patent. They have low toxicity and are useful in treating infections of skin and mucous membrane, and for major fungal infections such as visceral and septicaemia candidiasis in man and animals.
FR7319424A 1973-05-29 1973-05-29 3-Carbamoyloxy-5-methyl-isothiazoles - as antibacterial and antifungal agents for treating man and animals Granted FR2231370A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR7319424A FR2231370A2 (en) 1973-05-29 1973-05-29 3-Carbamoyloxy-5-methyl-isothiazoles - as antibacterial and antifungal agents for treating man and animals

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7319424A FR2231370A2 (en) 1973-05-29 1973-05-29 3-Carbamoyloxy-5-methyl-isothiazoles - as antibacterial and antifungal agents for treating man and animals

Publications (2)

Publication Number Publication Date
FR2231370A2 true FR2231370A2 (en) 1974-12-27
FR2231370B2 FR2231370B2 (en) 1976-10-22

Family

ID=9120147

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7319424A Granted FR2231370A2 (en) 1973-05-29 1973-05-29 3-Carbamoyloxy-5-methyl-isothiazoles - as antibacterial and antifungal agents for treating man and animals

Country Status (1)

Country Link
FR (1) FR2231370A2 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2354097A1 (en) * 1976-06-08 1978-01-06 Wyeth John & Brother Ltd THERAPEUTIC COMPOSITION OF THIAZOLIC DERIVATIVES AND ITS PREPARATION

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
NEANT *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2354097A1 (en) * 1976-06-08 1978-01-06 Wyeth John & Brother Ltd THERAPEUTIC COMPOSITION OF THIAZOLIC DERIVATIVES AND ITS PREPARATION

Also Published As

Publication number Publication date
FR2231370B2 (en) 1976-10-22

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