FR2215207A1 - Basic esters of (fluoroanthen-8-yl)-carboxylic acid - antispasmodic agents of low toxicity - Google Patents

Basic esters of (fluoroanthen-8-yl)-carboxylic acid - antispasmodic agents of low toxicity

Info

Publication number
FR2215207A1
FR2215207A1 FR7301141A FR7301141A FR2215207A1 FR 2215207 A1 FR2215207 A1 FR 2215207A1 FR 7301141 A FR7301141 A FR 7301141A FR 7301141 A FR7301141 A FR 7301141A FR 2215207 A1 FR2215207 A1 FR 2215207A1
Authority
FR
France
Prior art keywords
fluoroanthen
carboxylic acid
low toxicity
antispasmodic agents
basic esters
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7301141A
Other languages
French (fr)
Other versions
FR2215207B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Dr L Zambeletti SpA
Original Assignee
Dr L Zambeletti SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dr L Zambeletti SpA filed Critical Dr L Zambeletti SpA
Priority to FR7301141A priority Critical patent/FR2215207A1/en
Publication of FR2215207A1 publication Critical patent/FR2215207A1/en
Application granted granted Critical
Publication of FR2215207B1 publication Critical patent/FR2215207B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
    • C07D213/30—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C63/00—Compounds having carboxyl groups bound to a carbon atoms of six-membered aromatic rings
    • C07C63/33—Polycyclic acids
    • C07C63/49—Polycyclic acids containing rings other than six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40—Oxygen atoms
    • C07D211/44—Oxygen atoms attached in position 4
    • C07D211/46—Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Fluoranthen-8-ylcarboxylic acid esters of the formula: (where Y = -CH2CH2-NRR1 Z = fluoranthen-8-yl, R and R1 = same or different (1-4C) straight or branched alkyl, (5-6C) cycloalkyl or together with the attached N atom represents a 5 or 6 membered heterocyclic ring) and their acid addn salts have antispasmodic acitivity, but lower toxicity than atropine.
FR7301141A 1973-01-12 1973-01-12 Basic esters of (fluoroanthen-8-yl)-carboxylic acid - antispasmodic agents of low toxicity Granted FR2215207A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR7301141A FR2215207A1 (en) 1973-01-12 1973-01-12 Basic esters of (fluoroanthen-8-yl)-carboxylic acid - antispasmodic agents of low toxicity

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7301141A FR2215207A1 (en) 1973-01-12 1973-01-12 Basic esters of (fluoroanthen-8-yl)-carboxylic acid - antispasmodic agents of low toxicity

Publications (2)

Publication Number Publication Date
FR2215207A1 true FR2215207A1 (en) 1974-08-23
FR2215207B1 FR2215207B1 (en) 1976-03-05

Family

ID=9113236

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7301141A Granted FR2215207A1 (en) 1973-01-12 1973-01-12 Basic esters of (fluoroanthen-8-yl)-carboxylic acid - antispasmodic agents of low toxicity

Country Status (1)

Country Link
FR (1) FR2215207A1 (en)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2652417A (en) * 1951-10-06 1953-09-15 Warner Hudnut Inc 1, 2, 3, 10b-tetrahydrofluoranthene-10b-carboxylic acid
FR2021018A1 (en) * 1968-10-18 1970-07-17 Richardson Merrell Inc
GB1298529A (en) * 1970-05-16 1972-12-06 Zambeletti Spa L Basic esters derived from flouranthene and process for their preparation

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2652417A (en) * 1951-10-06 1953-09-15 Warner Hudnut Inc 1, 2, 3, 10b-tetrahydrofluoranthene-10b-carboxylic acid
FR2021018A1 (en) * 1968-10-18 1970-07-17 Richardson Merrell Inc
GB1298529A (en) * 1970-05-16 1972-12-06 Zambeletti Spa L Basic esters derived from flouranthene and process for their preparation

Also Published As

Publication number Publication date
FR2215207B1 (en) 1976-03-05

Similar Documents

Publication Publication Date Title
HU178577B (en) Process for producing phenoxy-phenoxy-propionic acic derivatives an herbicide compositions containing them as active agents
IE39578L (en) Imidazolyl-o,n-acetals
ES430709A1 (en) 1-(Imidazolyl-1)-2-aryloxy-3-hydroxy-alkanes
IE38920L (en) Flameproofing polyesters
ES8800197A1 (en) Quinolinecarboxylic acids with an antibacterial activity.
IE41440L (en) Thiatetracyclines
ZA774803B (en) 7-acylamino-8-oxo-3-oxa-1-azabicyclo-(4.2.0)octane-2-carboxylic acid derivatives
IE38979L (en) Tetrazolyl - quinoxalinecarboxamide derivatives
FR2540870B1 (en)
IE37490L (en) Benzoicacid derivatives and benzisothiazole 1,1 dioxides
IE43253L (en) Phosphinic acid halides.
ES443791A1 (en) Cephalosporins
FR2215207A1 (en) Basic esters of (fluoroanthen-8-yl)-carboxylic acid - antispasmodic agents of low toxicity
JPS543083A (en) Tetrahydro-1,3,5-thiadiazin-4-ones and insecticide-miticide containing the same
ES435969A1 (en) Indolobenzazepine derivatives
EP0042435A4 (en) Benzothiazine derivatives.
GB1177129A (en) Isoxazolidines and Tetrahydro-1,2-Isoxazine Compounds
ES480329A1 (en) Derivatives of benzoylphenoxyalkanoic acids having normolipemizing activity
ES8505996A1 (en) Sulfenamide derivatives, process for their preparation, and medicaments containing these compounds.
IE38268L (en) 4-phenyl ethers of 3-amino-5-sulphamoylbenzoic acids
ES394969A1 (en) 5-(2-amino-alkoxy-phenoxy-methyl)-3-alkyl-isoxazoles - useful as hypotensives and sedatives
ES449446A1 (en) 1-Oxo-1H-6-piperidinopyrimido{8 1,2-a{9 quinoline-2-carboxylic acids and esters
ES449917A1 (en) Substituted indanones
GB1041697A (en) Novel 6,7-dihydro-benzo[a]quinolizinium salts and a process for the preparation thereof
ES394968A1 (en) 5-(2-amino-alkoxy-phenoxy-methyl)-3-alkyl-isoxazoles - useful as hypotensives and sedatives

Legal Events

Date Code Title Description
ST Notification of lapse