FR21C1049I2 - PHARMACEUTICAL COMPOSITION COMPRISING CITRATE AND BICARBONATE SALTS, AND ITS USE FOR THE TREATMENT OF CYSTINURIA - Google Patents

PHARMACEUTICAL COMPOSITION COMPRISING CITRATE AND BICARBONATE SALTS, AND ITS USE FOR THE TREATMENT OF CYSTINURIA

Info

Publication number
FR21C1049I2
FR21C1049I2 FR21C1049C FR21C1049C FR21C1049I2 FR 21C1049 I2 FR21C1049 I2 FR 21C1049I2 FR 21C1049 C FR21C1049 C FR 21C1049C FR 21C1049 C FR21C1049 C FR 21C1049C FR 21C1049 I2 FR21C1049 I2 FR 21C1049I2
Authority
FR
France
Prior art keywords
cystinuria
citrate
treatment
pharmaceutical composition
bicarbonate salts
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
FR21C1049C
Other languages
French (fr)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Advicenne SA
Original Assignee
Advicenne SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=44146941&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=FR21C1049(I2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Advicenne SA filed Critical Advicenne SA
Publication of FR21C1049I1 publication Critical patent/FR21C1049I1/fr
Application granted granted Critical
Publication of FR21C1049I2 publication Critical patent/FR21C1049I2/en
Active legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2072Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2072Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/194Carboxylic acids, e.g. valproic acid having two or more carboxyl groups, e.g. succinic, maleic or phthalic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716Glucans
    • A61K31/717Celluloses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/74Synthetic polymeric materials
    • A61K31/745Polymers of hydrocarbons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/06Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/06Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • A61K33/10Carbonates; Bicarbonates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2072Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806Coating materials
    • A61K9/2833Organic macromolecular compounds
    • A61K9/286Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005Wall or coating material
    • A61K9/5021Organic macromolecular compounds
    • A61K9/5036Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/04Drugs for disorders of the urinary system for urolithiasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2009Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4808Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
FR21C1049C 2010-11-18 2021-10-27 PHARMACEUTICAL COMPOSITION COMPRISING CITRATE AND BICARBONATE SALTS, AND ITS USE FOR THE TREATMENT OF CYSTINURIA Active FR21C1049I2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR1059474A FR2967578B1 (en) 2010-11-18 2010-11-18 PHARMACEUTICAL COMPOSITION COMPRISING CITRATE AND BICARBONATE SALTS AND USE THEREOF FOR THE TREATMENT OF CYSTINURIA
PCT/FR2011/052697 WO2012066257A1 (en) 2010-11-18 2011-11-18 Pharmaceutical composition comprising citrate and bicarbonate salts, and use thereof for treating cystinuria

Publications (2)

Publication Number Publication Date
FR21C1049I1 FR21C1049I1 (en) 2021-12-10
FR21C1049I2 true FR21C1049I2 (en) 2022-09-30

Family

ID=44146941

Family Applications (2)

Application Number Title Priority Date Filing Date
FR1059474A Active FR2967578B1 (en) 2010-11-18 2010-11-18 PHARMACEUTICAL COMPOSITION COMPRISING CITRATE AND BICARBONATE SALTS AND USE THEREOF FOR THE TREATMENT OF CYSTINURIA
FR21C1049C Active FR21C1049I2 (en) 2010-11-18 2021-10-27 PHARMACEUTICAL COMPOSITION COMPRISING CITRATE AND BICARBONATE SALTS, AND ITS USE FOR THE TREATMENT OF CYSTINURIA

Family Applications Before (1)

Application Number Title Priority Date Filing Date
FR1059474A Active FR2967578B1 (en) 2010-11-18 2010-11-18 PHARMACEUTICAL COMPOSITION COMPRISING CITRATE AND BICARBONATE SALTS AND USE THEREOF FOR THE TREATMENT OF CYSTINURIA

Country Status (16)

Country Link
US (1) US9636304B2 (en)
EP (1) EP2640363B1 (en)
JP (1) JP5879359B2 (en)
KR (1) KR101699581B1 (en)
AU (1) AU2011331019B2 (en)
CA (1) CA2816660C (en)
DK (1) DK2640363T3 (en)
ES (1) ES2553424T3 (en)
FR (2) FR2967578B1 (en)
HU (1) HUE026230T2 (en)
IL (1) IL226373A (en)
MX (1) MX338975B (en)
NZ (1) NZ611026A (en)
PL (1) PL2640363T3 (en)
WO (1) WO2012066257A1 (en)
ZA (1) ZA201303695B (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11273140B2 (en) * 2013-06-06 2022-03-15 Stefanie A. Seixas-Mikelus Juice beverage for prevention and treatment of renal stones
FR3009496B1 (en) * 2013-08-12 2016-02-05 Mohamed Skiba MULTIPARTICULAR FORMS WITH PROLONGED RELEASE, PROCESS FOR THEIR PREPARATION AND COMPOSITIONS CONTAINING SAME FOR THE TREATMENT AND / OR PREVENTION OF CYCTINURIA
CA3067567A1 (en) * 2017-06-16 2018-12-20 Altibio, Inc. Modified-release tiopronin compositions, kits and methods for treating cystinuria and related disorders
US20230082078A1 (en) * 2021-08-24 2023-03-16 Laminaria Group Ab Sodium bicarbonate nutritional supplement

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3903255A (en) * 1971-05-17 1975-09-02 Rohm & Haas Effervescent potassium chloride tablet
HU165181B (en) 1971-11-08 1974-07-27
US4451454A (en) * 1981-06-16 1984-05-29 Wong Dennis W Prophylaxis and treatment of thromboembolic disorders in man and in warm-blooded animals with bicarbonate salts of alkali metals
GB2130087A (en) * 1982-09-22 1984-05-31 Dr Joachime Helbig Pharmaceutical oral dosage forms of an active agent capable of forming or releasing bicarbonate ions
JPS60197624A (en) * 1984-03-21 1985-10-07 Nippon Chemiphar Co Ltd Urine-alkalizing food composition
CA1326040C (en) 1989-11-16 1994-01-11 Neill B. Walsdorf Magnesium-potassium citrate
JP2941163B2 (en) * 1993-02-19 1999-08-25 武田薬品工業株式会社 Pet urinary stone disease treatment / prevention agent and treatment method
US5674529A (en) * 1995-06-06 1997-10-07 Church & Dwight Co., Inc. Alkalinizing potassium salt controlled release preparations
US5888544A (en) * 1996-06-20 1999-03-30 Gerhard Gergely Effervescent system for effervescent tablets and effervescent granules
EP1970066A1 (en) * 2007-03-12 2008-09-17 Medice Arzneimittel Pütter GmbH & Co. KG Pharmaceutical compound for treating acidaemia

Also Published As

Publication number Publication date
KR101699581B1 (en) 2017-01-24
JP5879359B2 (en) 2016-03-08
FR2967578B1 (en) 2012-12-28
CA2816660C (en) 2017-07-04
PL2640363T3 (en) 2016-01-29
US20130236545A1 (en) 2013-09-12
ZA201303695B (en) 2014-07-30
CA2816660A1 (en) 2012-05-24
AU2011331019A1 (en) 2013-06-13
ES2553424T3 (en) 2015-12-09
EP2640363B1 (en) 2015-08-26
JP2013542975A (en) 2013-11-28
AU2011331019B2 (en) 2016-04-07
MX338975B (en) 2016-05-06
FR2967578A1 (en) 2012-05-25
US9636304B2 (en) 2017-05-02
DK2640363T3 (en) 2015-12-14
FR21C1049I1 (en) 2021-12-10
NZ611026A (en) 2014-12-24
IL226373A0 (en) 2013-07-31
WO2012066257A1 (en) 2012-05-24
MX2013005482A (en) 2013-08-29
IL226373A (en) 2016-04-21
EP2640363A1 (en) 2013-09-25
KR20130119450A (en) 2013-10-31
HUE026230T2 (en) 2016-06-28

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