FR2198754B1 - - Google Patents

Info

Publication number
FR2198754B1
FR2198754B1 FR7332349A FR7332349A FR2198754B1 FR 2198754 B1 FR2198754 B1 FR 2198754B1 FR 7332349 A FR7332349 A FR 7332349A FR 7332349 A FR7332349 A FR 7332349A FR 2198754 B1 FR2198754 B1 FR 2198754B1
Authority
FR
France
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR7332349A
Other languages
French (fr)
Other versions
FR2198754A1 (US06582424-20030624-M00016.png
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Syntex USA LLC
Original Assignee
Syntex USA LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syntex USA LLC filed Critical Syntex USA LLC
Publication of FR2198754A1 publication Critical patent/FR2198754A1/fr
Application granted granted Critical
Publication of FR2198754B1 publication Critical patent/FR2198754B1/fr
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/08Bronchodilators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/04Drugs for genital or sexual disorders; Contraceptives for inducing labour or abortion; Uterotonics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00Ethers; Compounds having groups, groups or groups
    • C07C43/02Ethers
    • C07C43/03Ethers having all ether-oxygen atoms bound to acyclic carbon atoms
    • C07C43/14Unsaturated ethers
    • C07C43/17Unsaturated ethers containing halogen
    • C07C43/174Unsaturated ethers containing halogen containing six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/51Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition
    • C07C45/516Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition involving transformation of nitrogen-containing compounds to >C = O groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/587Unsaturated compounds containing a keto groups being part of a ring
    • C07C49/753Unsaturated compounds containing a keto groups being part of a ring containing ether groups, groups, groups, or groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D309/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/10Oxygen atoms
    • C07D309/12Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/38Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/40Esters thereof
    • C07F9/4003Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/4006Esters of acyclic acids which can have further substituents on alkyl

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Reproductive Health (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Endocrinology (AREA)
  • Pain & Pain Management (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pulmonology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR7332349A 1972-09-08 1973-09-07 Expired FR2198754B1 (US06582424-20030624-M00016.png)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US28733372A 1972-09-08 1972-09-08
US379127A US3867423A (en) 1972-09-08 1973-07-13 Difluoromethylene substituted prostaglandin derivatives

Publications (2)

Publication Number Publication Date
FR2198754A1 FR2198754A1 (US06582424-20030624-M00016.png) 1974-04-05
FR2198754B1 true FR2198754B1 (US06582424-20030624-M00016.png) 1976-09-03

Family

ID=26964400

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7332349A Expired FR2198754B1 (US06582424-20030624-M00016.png) 1972-09-08 1973-09-07

Country Status (13)

Country Link
US (1) US3867423A (US06582424-20030624-M00016.png)
JP (1) JPS4992055A (US06582424-20030624-M00016.png)
AT (1) AT340071B (US06582424-20030624-M00016.png)
CA (1) CA1041496A (US06582424-20030624-M00016.png)
CH (4) CH602626A5 (US06582424-20030624-M00016.png)
DE (1) DE2344740A1 (US06582424-20030624-M00016.png)
ES (1) ES418575A1 (US06582424-20030624-M00016.png)
FR (1) FR2198754B1 (US06582424-20030624-M00016.png)
GB (1) GB1414881A (US06582424-20030624-M00016.png)
HK (1) HK75276A (US06582424-20030624-M00016.png)
IL (1) IL42995A (US06582424-20030624-M00016.png)
MY (1) MY7700075A (US06582424-20030624-M00016.png)
NL (1) NL7312390A (US06582424-20030624-M00016.png)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5120803U (US06582424-20030624-M00016.png) * 1974-07-31 1976-02-16
US4001295A (en) * 1975-06-23 1977-01-04 Syntex (U.S.A.) Inc. 11,12-difluoromethylene substituted prostanoic and prost-5-cis-enoic acid derivatives
US4188329A (en) * 1975-09-08 1980-02-12 Abbott Laboratories Intermediates for the preparation of prostaglandins and prostaglandin analogs from a mold metabolite
EP0329184A3 (en) * 1988-02-19 1990-05-23 Neorx Corporation Antimers and antimeric conjugation

Also Published As

Publication number Publication date
DE2344740A1 (de) 1974-03-21
IL42995A0 (en) 1973-11-28
CH602626A5 (US06582424-20030624-M00016.png) 1978-07-31
JPS4992055A (US06582424-20030624-M00016.png) 1974-09-03
HK75276A (en) 1976-12-10
GB1414881A (en) 1975-11-19
CA1041496A (en) 1978-10-31
US3867423A (en) 1975-02-18
AU5974773A (en) 1975-03-06
FR2198754A1 (US06582424-20030624-M00016.png) 1974-04-05
AT340071B (de) 1977-11-25
CH595343A5 (US06582424-20030624-M00016.png) 1978-02-15
ES418575A1 (es) 1977-05-01
MY7700075A (en) 1977-12-31
NL7312390A (US06582424-20030624-M00016.png) 1974-03-12
CH595342A5 (US06582424-20030624-M00016.png) 1978-02-15
ATA778173A (de) 1977-03-15
CH596167A5 (US06582424-20030624-M00016.png) 1978-02-28
IL42995A (en) 1978-03-10

Similar Documents

Publication Publication Date Title
JPS4950367U (US06582424-20030624-M00016.png)
JPS5021911Y2 (US06582424-20030624-M00016.png)
JPS5122088B2 (US06582424-20030624-M00016.png)
CS152194B1 (US06582424-20030624-M00016.png)
CS155999B2 (US06582424-20030624-M00016.png)
CS156330B1 (US06582424-20030624-M00016.png)
CH568828A5 (US06582424-20030624-M00016.png)
CH570574A5 (US06582424-20030624-M00016.png)
BG18632A1 (US06582424-20030624-M00016.png)
BG18690A1 (US06582424-20030624-M00016.png)
BG19316A1 (US06582424-20030624-M00016.png)
CH1169172A4 (US06582424-20030624-M00016.png)
CH1332472A4 (US06582424-20030624-M00016.png)
CH311672A4 (US06582424-20030624-M00016.png)
CH562467A (US06582424-20030624-M00016.png)
CH564525A5 (US06582424-20030624-M00016.png)
CH565906A5 (US06582424-20030624-M00016.png)
CH565917A5 (US06582424-20030624-M00016.png)
CH565970A5 (US06582424-20030624-M00016.png)
CH566667A5 (US06582424-20030624-M00016.png)
CH566801A5 (US06582424-20030624-M00016.png)
CH567026A5 (US06582424-20030624-M00016.png)
CH567672A5 (US06582424-20030624-M00016.png)
CH567873A5 (US06582424-20030624-M00016.png)
BG19386A1 (US06582424-20030624-M00016.png)

Legal Events

Date Code Title Description
ST Notification of lapse