ATA778173A - Verfahren zur herstellung von neuen difluormethylen-substituierten prostaglandinderivaten - Google Patents
Verfahren zur herstellung von neuen difluormethylen-substituierten prostaglandinderivatenInfo
- Publication number
- ATA778173A ATA778173A AT778173A AT778173A ATA778173A AT A778173 A ATA778173 A AT A778173A AT 778173 A AT778173 A AT 778173A AT 778173 A AT778173 A AT 778173A AT A778173 A ATA778173 A AT A778173A
- Authority
- AT
- Austria
- Prior art keywords
- difluoromethylene
- prostaglandin derivatives
- manufacturing new
- substituted prostaglandin
- substituted
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 150000003180 prostaglandins Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
- C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/04—Drugs for genital or sexual disorders; Contraceptives for inducing labour or abortion; Uterotonics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C43/00—Ethers; Compounds having groups, groups or groups
- C07C43/02—Ethers
- C07C43/03—Ethers having all ether-oxygen atoms bound to acyclic carbon atoms
- C07C43/14—Unsaturated ethers
- C07C43/17—Unsaturated ethers containing halogen
- C07C43/174—Unsaturated ethers containing halogen containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/51—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition
- C07C45/516—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition involving transformation of nitrogen-containing compounds to >C = O groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
- C07C49/753—Unsaturated compounds containing a keto groups being part of a ring containing ether groups, groups, groups, or groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/10—Oxygen atoms
- C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/40—Esters thereof
- C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
- C07F9/4006—Esters of acyclic acids which can have further substituents on alkyl
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Reproductive Health (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Gynecology & Obstetrics (AREA)
- Pregnancy & Childbirth (AREA)
- Endocrinology (AREA)
- Pain & Pain Management (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pulmonology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US28733372A | 1972-09-08 | 1972-09-08 | |
US379127A US3867423A (en) | 1972-09-08 | 1973-07-13 | Difluoromethylene substituted prostaglandin derivatives |
Publications (2)
Publication Number | Publication Date |
---|---|
ATA778173A true ATA778173A (de) | 1977-03-15 |
AT340071B AT340071B (de) | 1977-11-25 |
Family
ID=26964400
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT778173A AT340071B (de) | 1972-09-08 | 1973-09-07 | Verfahren zur herstellung von neuen difluormethylen-substituierten prostaglandinderivaten |
Country Status (13)
Country | Link |
---|---|
US (1) | US3867423A (de) |
JP (1) | JPS4992055A (de) |
AT (1) | AT340071B (de) |
CA (1) | CA1041496A (de) |
CH (4) | CH596167A5 (de) |
DE (1) | DE2344740A1 (de) |
ES (1) | ES418575A1 (de) |
FR (1) | FR2198754B1 (de) |
GB (1) | GB1414881A (de) |
HK (1) | HK75276A (de) |
IL (1) | IL42995A (de) |
MY (1) | MY7700075A (de) |
NL (1) | NL7312390A (de) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5120803U (de) * | 1974-07-31 | 1976-02-16 | ||
US4001295A (en) * | 1975-06-23 | 1977-01-04 | Syntex (U.S.A.) Inc. | 11,12-difluoromethylene substituted prostanoic and prost-5-cis-enoic acid derivatives |
US4188329A (en) * | 1975-09-08 | 1980-02-12 | Abbott Laboratories | Intermediates for the preparation of prostaglandins and prostaglandin analogs from a mold metabolite |
EP0329184A3 (de) * | 1988-02-19 | 1990-05-23 | Neorx Corporation | Antimere und antimere Konjugation |
-
1973
- 1973-07-13 US US379127A patent/US3867423A/en not_active Expired - Lifetime
- 1973-08-15 CA CA179,099A patent/CA1041496A/en not_active Expired
- 1973-08-15 IL IL42995A patent/IL42995A/xx unknown
- 1973-08-29 GB GB4073673A patent/GB1414881A/en not_active Expired
- 1973-09-05 DE DE19732344740 patent/DE2344740A1/de active Pending
- 1973-09-06 CH CH227477A patent/CH596167A5/xx not_active IP Right Cessation
- 1973-09-06 CH CH227377A patent/CH595342A5/xx not_active IP Right Cessation
- 1973-09-06 CH CH227577A patent/CH595343A5/xx not_active IP Right Cessation
- 1973-09-06 CH CH1282273A patent/CH602626A5/xx not_active IP Right Cessation
- 1973-09-07 JP JP48101000A patent/JPS4992055A/ja active Pending
- 1973-09-07 ES ES418575A patent/ES418575A1/es not_active Expired
- 1973-09-07 AT AT778173A patent/AT340071B/de not_active IP Right Cessation
- 1973-09-07 FR FR7332349A patent/FR2198754B1/fr not_active Expired
- 1973-09-07 NL NL7312390A patent/NL7312390A/xx not_active Application Discontinuation
-
1976
- 1976-12-02 HK HK752/76*UA patent/HK75276A/xx unknown
-
1977
- 1977-12-30 MY MY75/77A patent/MY7700075A/xx unknown
Also Published As
Publication number | Publication date |
---|---|
FR2198754B1 (de) | 1976-09-03 |
IL42995A0 (en) | 1973-11-28 |
IL42995A (en) | 1978-03-10 |
US3867423A (en) | 1975-02-18 |
AT340071B (de) | 1977-11-25 |
CH602626A5 (de) | 1978-07-31 |
CH595342A5 (de) | 1978-02-15 |
FR2198754A1 (de) | 1974-04-05 |
AU5974773A (en) | 1975-03-06 |
HK75276A (en) | 1976-12-10 |
GB1414881A (en) | 1975-11-19 |
NL7312390A (de) | 1974-03-12 |
CA1041496A (en) | 1978-10-31 |
DE2344740A1 (de) | 1974-03-21 |
ES418575A1 (es) | 1977-05-01 |
CH596167A5 (de) | 1978-02-28 |
MY7700075A (en) | 1977-12-31 |
JPS4992055A (de) | 1974-09-03 |
CH595343A5 (de) | 1978-02-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ELJ | Ceased due to non-payment of the annual fee |